Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rita Cicatiello"'
Autor:
Nunzia Mollo, Miriam Aurilia, Roberta Scognamiglio, Lucrezia Zerillo, Rita Cicatiello, Ferdinando Bonfiglio, Pasqualina Pagano, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izzo
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Down syndrome is a neurodevelopmental disorder frequently characterized by other developmental defects, such as congenital heart disease. Analysis of gene expression profiles of hearts from trisomic fetuses have shown upregulation of extracellular ma
Externí odkaz:
https://doaj.org/article/6f3f852b01ea4178816acde55f113e27
Autor:
Elena Longobardi, Francesco Miceli, Agnese Secondo, Rita Cicatiello, Antonella Izzo, Nadia Tinto, Sebastien Moutton, Frédéric Tran Mau-Them, Antonio Vitobello, Maurizio Taglialatela
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102311- (2021)
Heterozygous variants in the KCNQ3 gene cause epileptic and/or developmental disorders of varying severity. Here we describe the generation of induced pluripotent stem cells (iPSCs) from a 9-year-old girl with pharmacodependent neonatal-onset epileps
Externí odkaz:
https://doaj.org/article/93963da4c1d646249d0cb4f2945f3f7f
Autor:
Nunzia Mollo, Maria Nitti, Lucrezia Zerillo, Deriggio Faicchia, Teresa Micillo, Rossella Accarino, Agnese Secondo, Tiziana Petrozziello, Gaetano Calì, Rita Cicatiello, Ferdinando Bonfiglio, Viviana Sarnataro, Rita Genesio, Antonella Izzo, Paolo Pinton, Giuseppe Matarese, Simona Paladino, Anna Conti, Lucio Nitsch
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e7a461318e36402eb25ecba9b05896ba
Autor:
Antonella Izzo, Nunzia Mollo, Maria Nitti, Simona Paladino, Gaetano Calì, Rita Genesio, Ferdinando Bonfiglio, Rita Cicatiello, Maria Barbato, Viviana Sarnataro, Anna Conti, Lucio Nitsch
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-8 (2018)
Abstract Trisomy of chromosome 21 (TS21) is the most common autosomal aneuploidy compatible with postnatal survival with a prevalence of 1 in 700 newborns. Its phenotype is highly complex with constant features, such as mental retardation, dysmorphic
Externí odkaz:
https://doaj.org/article/4ee9b0798112484caf1c2a218a487dab
Autor:
Nunzia Mollo, Matteo Esposito, Miriam Aurilia, Roberta Scognamiglio, Rossella Accarino, Ferdinando Bonfiglio, Rita Cicatiello, Maria Charalambous, Claudio Procaccini, Teresa Micillo, Rita Genesio, Gaetano Calì, Agnese Secondo, Simona Paladino, Giuseppe Matarese, Gabriella De Vita, Anna Conti, Lucio Nitsch, Antonella Izzo
Publikováno v:
Biology, Vol 10, Iss 7, p 609 (2021)
Background: The presence of mitochondrial alterations in Down syndrome suggests that it might affect neuronal differentiation. We established a model of trisomic iPSCs, differentiating into neural precursor cells (NPCs) to monitor the occurrence of d
Externí odkaz:
https://doaj.org/article/e283770a81d44bdaa3143288d2f1f94a
Autor:
Nunzia Mollo, Maria Nitti, Lucrezia Zerillo, Deriggio Faicchia, Teresa Micillo, Rossella Accarino, Agnese Secondo, Tiziana Petrozziello, Gaetano Calì, Rita Cicatiello, Ferdinando Bonfiglio, Viviana Sarnataro, Rita Genesio, Antonella Izzo, Paolo Pinton, Giuseppe Matarese, Simona Paladino, Anna Conti, Lucio Nitsch
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Mitochondrial dysfunction plays a primary role in neurodevelopmental anomalies and neurodegeneration of Down syndrome (DS) subjects. For this reason, targeting mitochondrial key genes, such as PGC-1α/PPARGC1A, is emerging as a good therapeutic appro
Externí odkaz:
https://doaj.org/article/8a750e35c731476aaf9c71b295b4d1b3
Autor:
Nunzia Mollo, Rita Cicatiello, Miriam Aurilia, Roberta Scognamiglio, Rita Genesio, Maria Charalambous, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izzo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3134 (2020)
Mitochondria are organelles that mainly control energy conversion in the cell. In addition, they also participate in many relevant activities, such as the regulation of apoptosis and calcium levels, and other metabolic tasks, all closely linked to ce
Externí odkaz:
https://doaj.org/article/b2644e2fc8774d4c90b4ccd610b894e1
Autor:
Antonella Izzo, Rosanna Manco, Tiziana de Cristofaro, Ferdinando Bonfiglio, Rita Cicatiello, Nunzia Mollo, Marco De Martino, Rita Genesio, Mariastella Zannini, Anna Conti, Lucio Nitsch
Publikováno v:
International Journal of Genomics, Vol 2017 (2017)
Dosage-dependent upregulation of most of chromosome 21 (Hsa21) genes has been demonstrated in heart tissues of fetuses with Down syndrome (DS). Also miRNAs might play important roles in the cardiac phenotype as they are highly expressed in the heart
Externí odkaz:
https://doaj.org/article/97f028a9da27488e96b539718db24af1
Autor:
Rita Cicatiello, Piero Pignataro, Antonella Izzo, Nunzia Mollo, Lucia Pezone, Giuseppe Maria Maruotti, Laura Sarno, Gabriella Sglavo, Anna Conti, Rita Genesio, Lucio Nitsch
Publikováno v:
Medical Sciences, Vol 7, Iss 3, p 40 (2019)
We have carried out a retrospective study of chromosome anomalies associated with increased nuchal translucency (NT) in order to compare yield rates of karyotype, chromosome microarray analysis (CMA), and non-invasive prenatal testing (NIPT) in this
Externí odkaz:
https://doaj.org/article/8b46745ba9e343e3bc2ce8f9cb7c3e76
Autor:
Miriam Aurilia, Matteo Esposito, Giuseppe Matarese, Teresa Micillo, Agnese Secondo, Lucio Nitsch, Rita Genesio, Simona Paladino, Maria Charalambous, Anna Conti, Nunzia Mollo, Roberta Scognamiglio, Antonella Izzo, Gabriella De Vita, Rita Cicatiello, Gaetano Calì, Rossella Accarino, Claudio Procaccini, Ferdinando Bonfiglio
Publikováno v:
Biology
Biology, Vol 10, Iss 609, p 609 (2021)
Volume 10
Issue 7
Biology (Basel)
Biology, Vol 10, Iss 609, p 609 (2021)
Volume 10
Issue 7
Biology (Basel)
Simple Summary Down Syndrome, which is due to the presence of three copies of chromosome 21, always presents with mental retardation, possibly caused by defects in the development of neurons. In recent years, it has been shown that cells and tissues