Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rita Bisogni"'
Autor:
Simona Romano, Anna D’Angelillo, Paolo D’Arrigo, Stefania Staibano, Adelaide Greco, Arturo Brunetti, Massimiliano Scalvenzi, Rita Bisogni, Iris Scala, Maria Fiammetta Romano
Publikováno v:
Clinical and Translational Medicine, Vol 3, Iss 1, Pp n/a-n/a (2014)
Abstract Background FKBP51 (FKBP5 Official Symbol) is a large molecular weight component of the family of FK506 binding proteins (FKBP). In recent years, research studies from our laboratory highlighted functions for FKBP51 in the control of apoptosi
Externí odkaz:
https://doaj.org/article/065552bab03d45b583756d57ecef83dc
Autor:
Simona Romano, Maria Mallardo, Federico Chiurazzi, Rita Bisogni, Anna D’Angelillo, Raffaele Liuzzi, Giovanna Compare, Maria Fiammetta Romano
Publikováno v:
Haematologica, Vol 93, Iss 7 (2008)
Background Loss of response to transforming growth factor-beta (TGF-β ) is thought to contribute to the progression of chronic lymphocytic leukemia. Recent findings of over-activation of the TGF-β signal in FKBP12-knockout mouse prompted us to inve
Externí odkaz:
https://doaj.org/article/74ce63a8451c4582b2fc321e72dde488
Autor:
Simona Romano, Paolo D'Arrigo, Michele Polimeno, Stefano Messina, Paolo Ferraro, Nicola Corcione, Anna D'Angelillo, Maria Fiammetta Romano, Rita Bisogni, Paolo Pepino, Arturo Giordano
Publikováno v:
Vascular Pharmacology. 61:63-71
Tirofiban is a fibrinogen receptor antagonist, generated using the tripeptide Arg-Gly-Asp (RGD) as a template. RGD activates integrin receptors and integrin-mediated signals are necessary for normal cells to promote survival and stimulate cell cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b69fc091ae90c87fd641c52fd74dbc8
https://doi.org/10.1016/j.vph.2014.04.002
https://doi.org/10.1016/j.vph.2014.04.002
Autor:
Simona Romano, Antonio Sorrentino, Maria Fiammetta Romano, Rita Bisogni, Anna Laura Di Pace, Luigi Sivero
Publikováno v:
Scopus-Elsevier
FK506 binding proteins (FKBPs) are the intracellular ligands of FK506 and rapamycin, two natural compounds with powerful and clinically efficient immunosuppressive activity. In recent decades, a relevant role for immunosuppressants as anticancer agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3ca0f289be5cb1ce66e057fe5900a0
https://doi.org/10.2174/187152010794479816
https://doi.org/10.2174/187152010794479816
Autor:
S Volpe, Salvatore Venuta, Rosa Lerose, M F Romano, Arturo Leone, G Pagliuca, Rita Bisogni, Michelina Festa, G Storti, Maria Caterina Turco, Federico Chiurazzi
Publikováno v:
Cell Death & Differentiation. 10:383-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc15b743a2599c09b1e1b767287717f7
https://doi.org/10.1038/sj.cdd.4401167
https://doi.org/10.1038/sj.cdd.4401167
Autor:
Maria Romano, Vincenzo Poggi, Simona Romano, Annalisa Lamberti, Raffaella Avellino, Salvatore Venuta, Rita Bisogni, Rosanna Parasole
Publikováno v:
Blood. 106:1400-1406
The phosphatidyl-inositol 3 kinase (PI3k)/Akt pathway has been implicated in childhood acute lymphoblastic leukemia (ALL). Because rapamycin suppresses the oncogenic processes sustained by PI3k/Akt, we investigated whether rapamycin affects blast sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e936f4f3434964592b5277b654ac4e1a
https://doi.org/10.1182/blood-2005-03-0929
https://doi.org/10.1182/blood-2005-03-0929
Autor:
Salvatore Venuta, Maria Romano, Rita Bisogni, Simona Romano, Antonello Petrella, Raffaella Avellino
Publikováno v:
European Journal of Cancer. 40:2829-2836
Inhibition of nuclear factor (NF)-kappaB/Rel can sensitise many tumour cells to death-inducing stimuli, including chemotherapeutic agents, and there are data suggesting that disruption of NF-kappaB may be of therapeutic interest in melanoma. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76093175528097248cdd0466d721ab43
https://doi.org/10.1016/j.ejca.2004.08.017
https://doi.org/10.1016/j.ejca.2004.08.017
Autor:
Iris Scala, Paolo D'Arrigo, Adelaide Greco, Anna D'Angelillo, Massimiliano Scalvenzi, Maria Romano, Arturo Brunetti, Rita Bisogni, Simona Romano, Stefania Staibano
Publikováno v:
Clinical and Translational Medicine, Vol 3, Iss 1, Pp n/a-n/a (2014)
Clinical and Translational Medicine
Clinical and Translational Medicine
Background FKBP51 (FKBP5 Official Symbol) is a large molecular weight component of the family of FK506 binding proteins (FKBP). In recent years, research studies from our laboratory highlighted functions for FKBP51 in the control of apoptosis and mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5ab591033b3f2d5c0866cbffe52126
https://doi.org/10.1186/2001-1326-3-1
https://doi.org/10.1186/2001-1326-3-1
Autor:
Rosanna Martinelli, Roberto Pacelli, Simona Romano, Paolo D'Arrigo, Rita Bisogni, Anna D'Angelillo, Luigi Sivero, Stefania Staibano
The treatment of metastatic melanoma is challenging and in the vast majority of cases unsuccessful. Melanoma cells are resistant to most standard therapeutics. We have recently demonstrated that FKBP51 regulates melanoma response to ionizing radiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d17b6c325d79262dfe550e80fc1a26
http://hdl.handle.net/11386/4447657
http://hdl.handle.net/11386/4447657
Autor:
G Storti, Pierfrancesco Tassone, L Del Vecchio, Salvatore Venuta, Annalisa Lamberti, Rita Bisogni, M F Romano, D Pagnini, Maria Caterina Turco
Publikováno v:
Scopus-Elsevier
The activity of NF-kappa B/Rel nuclear factors is known to inhibit apoptosis in various cell types. We investigated whether the subtraction of NF-kappa B/Rel activity influenced the response of 11 AML (M1, M2 and M4) patients' cells to AraC. To this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ec2f5b65b953709a538f75dcfb4aee
https://doi.org/10.1038/sj.gt.3301216
https://doi.org/10.1038/sj.gt.3301216