Výsledky vyhledávání - "Rita Balice-Gordon"

Akademický článek

The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey

Autor: Tara L. Moore, Damon A. Young, Ronald J. Killiany, Kari R. Fonseca, Dmitri Volfson, David L. Gray, Rita Balice-Gordon, Rouba Kozak

Publikováno v: Frontiers in Aging Neuroscience, Vol 13 (2021)

Aged-related declines in cognition, especially working memory and executive function, begin in middle-age and these abilities are known to be mediated by the prefrontal cortex (PFC) and more specifically the dopamine (DA) system within the PFC. In bo

Externí odkaz: https://doaj.org/article/de9abf602a974353b8531c96d2cb9afe

Zobrazit plný text záznamu

Resolving neuroinflammation in AD

Autor: Niels Plath, Rita Balice‐Gordon

Publikováno v: Alzheimer's & Dementia. 18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bca847c5e11563774f0591e360bff7e
https://doi.org/10.1002/alz.059643

Zobrazit plný text záznamu

A Neurofunctional Domains Approach to Evaluate D1/D5 Dopamine Receptor Partial Agonism on Cognition and Motivation in Healthy Volunteers With Low Working Memory Capacity

Autor: Gabriel H Braley, Rita Balice-Gordon, Zhiyong Xie, Melissa Naylor, Brian T. Harel, Wenlei Liu, Rouba Kozak, Lovingly Park, Estibaliz Arce, Garry D. Honey, David Gray, Sridhar Duvvuri, Christopher H. Chatham, Nicholas DeMartinis

Publikováno v: International Journal of Neuropsychopharmacology

BackgroundDopamine D1 receptor signaling plays key roles in core domains of neural function, including cognition and reward processing; however, many questions remain about the functions of circuits modulated by dopamine D1 receptor, largely because

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf55c7a013c49047909a42b3c0e5eb4c
http://europepmc.org/articles/PMC7251631

Zobrazit plný text záznamu

A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index

Autor: Julia J. Schubert, Mattia Veronese, Tim D. Fryer, Roido Manavaki, Manfred G. Kitzbichler, Maria A. Nettis, Valeria Mondelli, Carmine M. Pariante, Edward T. Bullmore, Federico E. Turkheimer, Dominika Wlazly, Amber Dickinson, Andy Foster, Clare Knight, Claire Leckey, Paul Morgan, Angharad Morgan, Caroline O'Hagan, Samuel Touchard, Shahid Khan, Phil Murphy, Christine Parker, Jai Patel, Jill Richardson, Paul Acton, Nigel Austin, Anindya Bhattacharya, Nick Carruthers, Peter de Boer, Wayne Drevets, John Isaac, Declan Jones, John Kemp, Hartmuth Kolb, Jeff Nye, Gayle Wittenberg, Gareth Barker, Anna Bogdanova, Heidi Byrom, Diana Cash, Annamaria Cattaneo, Daniela Enache, Tony Gee, Caitlin Hastings, Melisa Kose, Giulia Lombardo, Nicole Mariani, Anna McLaughlin, Maria Nettis, Naghmeh Nikkheslat, Carmine Pariante, Karen Randall, Julia Schubert, Luca Sforzini, Hannah Sheridan, Camilla Simmons, Nisha Singh, Federico Turkheimer, Vicky Van Loo, Marta Vicente Rodriguez, Toby Wood, Courtney Worrell, Zuzanna Zajkowska, Brian Campbell, Jan Egebjerg, Hans Eriksson, Francois Gastambide, Karen Husted Adams, Ross Jeggo, Thomas Moeller, Bob Nelson, Niels Plath, Christian Thomsen, Jan Torleif Pederson, Stevin Zorn, Catherine Deith, Scott Farmer, John McClean, Andrew McPherson, Nagore Penandes, Paul Scouller, Murray Sutherland, Mary Jane Attenburrow, Jithen Benjamin, Helen Jones, Fran Mada, Akintayo Oladejo, Katy Smith, Rita Balice-Gordon, Brendon Binneman, James Duerr, Terence Fullerton, Veeru Goli, Zoe Hughes, Justin Piro, Tarek Samad, Jonathan Sporn, Liz Hoskins, Charmaine Kohn, Lauren Wilcock, Franklin Aigbirhio, Junaid Bhatti, Ed Bullmore, Sam Chamberlain, Marta Correia, Anna Crofts, Tim Fryer, Martin Graves, Alex Hatton, Manfred Kitzbichler, Mary-Ellen Lynall, Christina Maurice, Ciara O'Donnell, Linda Pointon, Peter St George Hyslop, Lorinda Turner, Petra Vertes, Barry Widmer, Guy Williams, Jonathan Cavanagh, Alison McColl, Robin Shaw, Erik Boddeke, Alison Baird, Stuart Clare, Phil Cowen, I-Shu (Dante) Huang, Sam Hurley, Simon Lovestone, Alejo Nevado-Holgado, Elena Ribe, Anviti Vyas, Laura Winchester, Madeleine Cleal, Diego Gomez-Nicola, Renzo Mancuso, Hugh Perry, Mara Cercignani, Charlotte Clarke, Alessandro Colasanti, Neil Harrison, Rosemary Murray, Jason O'Connor, Howard Mount

Publikováno v: Biological Psychiatry. Cognitive Neuroscience and Neuroimaging

Background: Immune mechanisms have been implicated in the pathogenesis of depression. Translocator protein (TSPO)–targeted positron emission tomography (PET) has been used to assess neuroinflammation in major depressive disorder. We aimed to 1) tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2204ff869f9b3d8a8b56521d5dd1f9c9
http://hdl.handle.net/11577/3411540

Zobrazit plný text záznamu

A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/D5 receptor partial agonist (PF-06412562) in patients with stable schizophrenia

Autor: Estibaliz Arce, Sridhar Duvvuri, Nicholas DeMartinis, David Gray, Brian T. Harel, Zhiyong Xie, Rouba Kozak, Rita Balice-Gordon, Melissa Naylor

Publikováno v: Journal of psychopharmacology (Oxford, England). 33(10)

Background: PF-06412562 is an orally bioavailable, selective dopamine D1/D5 receptor partial agonist with a non-catechol structure under evaluation for treatment of cognitive impairment in schizophrenia. Aims: This randomized, double-blind, placebo-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f2c872ec7442f14ce94a9f84a24871
https://pubmed.ncbi.nlm.nih.gov/31264510

Zobrazit plný text záznamu

Genetic and real-world clinical data, combined with empirical validation, nominate JAK-STAT signaling as a target for Alzheimer’s Disease therapeutic development

Autor: Rita Balice-Gordon, Nicole Mariani, Guy Williams, Miguel Angel Mayer, Federico Turkheimer, Naghmeh Nikkheslat, Jill Richardson, Dr Zuzanna Zajkowska, Tobias Wood, Elena Ribe, Alejo Nevado-Holgado, Diana Cash

Publikováno v: Cells, Vol 8, Iss 5, p 425 (2019)
Cells
Volume 8
Issue 5

As genome-wide association studies (GWAS) have grown in size, the number of genetic variants that have been associated per disease has correspondingly increased. Despite this increase in the number of single-nucleotide polymorphisms (SNPs) identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef8334ded5a16e0805f3f46faefd91a
https://eprints.gla.ac.uk/185620/1/185620.pdf

Zobrazit plný text záznamu

Neuroscience Training for the 21st Century

Autor: Rita Balice-Gordon, Edda Thiels, Walter J. Koroshetz, Todd Sherer, Huda Akil, Sheena M M. Posey Norris, David Lopes Cardozo, S. Murray Sherman

Publikováno v: Neuron. 90(5)

The field of neuroscience is enjoying a rapid expansion in scope, coupled with a remarkable broadening of conceptual approaches, scientific tools, and clinical applications. This growth poses new challenges for academic training programs as they prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7805523d2c373a721bb464cd2f37cc37
https://pubmed.ncbi.nlm.nih.gov/27253446

Zobrazit plný text záznamu

Cellular, synaptic, and circuit effects of antibodies in autoimmune CNS synaptopathies

Autor: Ankit, Jain, Rita, Balice-Gordon

Publikováno v: Handbook of clinical neurology. 133

Recently, clinicians have identified overlapping but distinguishable encephalitides, each associated with antibodies in serum and cerebrospinal fluid directed against specific cell surface proteins. The antibody targets identified to date are protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::809fa93d3383ca8deecbbaa72cf47451
https://pubmed.ncbi.nlm.nih.gov/27112672

Zobrazit plný text záznamu

Rigor or mortis: best practices for preclinical research in neuroscience

Autor: Rita Balice-Gordon, Oswald Steward

Publikováno v: Neuron. 84(3)

Numerous recent reports document a lack of reproducibility of preclinical studies, raising concerns about potential lack of rigor. Examples of lack of rigor have been extensively documented and proposals for practices to improve rigor are appearing.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108972409a33f3d20ab988f0fa3eabdf
https://pubmed.ncbi.nlm.nih.gov/25442936

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání