Výsledky vyhledávání - "Rita Holtwick"

Sphingosine 1-phosphate (S1P) induces expression of E-selectin and adhesion of monocytes via intracellular signalling pathways in vascular endothelial cells

Autor: Rita Holtwick, W. Völker, Tobias Weis, Annette Schmidt, Manaf Al Chahaf

Publikováno v: European Journal of Cell Biology. 89:733-741

Sphingosine 1-phosphate (S1P) – a constitutive component of human plasma – is implicated as a signalling molecule in the regulation of cell adhesion molecules (CAM) in vascular endothelial cells (EC), but the degree of the S1P-induced expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9be1053a55de9586ee88a3dbf67310
https://doi.org/10.1016/j.ejcb.2010.06.011

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Hypervolemic hypertension in mice with systemic inactivation of the (floxed) guanylyl cyclase-A gene by ?MHC-Cre-mediated recombination

Autor: Michaela Kuhn, Rita Holtwick, Boris V. Skryabin, Paulus Kirchhof, Alexander Bubikat, Markus N. Kruse, Melanie Voss, Larissa Fabritz, Jörg Stypmann, Ilka Veltrup, Karim Sabrane

Publikováno v: genesis. 39:288-298

To dissect the tissue-specific functions of atrial natriuretic peptide (ANP), we recently introduced loxP sites into the murine gene for its receptor, guanylyl cyclase-A (GC-A), by homologous recombination (tri-lox GC-A). For either smooth-muscle or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a509f9cec9cf2c3750d8cd3cbacfbea
https://doi.org/10.1002/gene.20056

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Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A

Autor: Rita Holtwick, Boris V. Skryabin, Frank Begrow, Alexander Bubikat, Hideo A. Baba, Martin van Eickels, Michael D. Schneider, David L. Garbers, Michaela Kuhn

Publikováno v: Journal of Clinical Investigation. 111:1399-1407

Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Atrial natriuretic peptide (ANP) has been postulated to exert local antihypertrophic effects in the heart. Thus, a loss of function of the ANP receptor guanylyl c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3712ba3124f3322a7d587da5f4ac2f
https://doi.org/10.1172/jci17061

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Left But Not Right Cardiac Hypertrophy in Atrial Natriuretic Peptide Receptor–Deficient Mice Is Prevented by Angiotensin Type 1 Receptor Antagonist Losartan

Autor: Elisabeth Ehler, Joseph Gehrmann, Michaela Kuhn, Melanie Vobeta, Rita Holtwick, Melanie Pierkes, Dorothée Risse, Hideo Baba

Publikováno v: Journal of Cardiovascular Pharmacology. 40:725-734

Mice with a genetic deletion of the atrial natriuretic peptide (ANP) receptor, guanylyl cyclase A (GC-A -/-), have chronic arterial hypertension and cardiac hypertrophy from the first day of life. To characterize the role of the angiotensin II and en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb831b295efb44f1ea368fc3ea0ec3f6
https://doi.org/10.1097/00005344-200211000-00010

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Increased effects of C-type natriuretic peptide on cardiac ventricular contractility and relaxation in guanylyl cyclase A-deficient mice

Autor: Rita Holtwick, Melanie Pierkes, Michaela Kuhn, Stepan Gambaryan, Regine Potthast, Wilhelm Schmitz, Peter Boknik, Suzanne M. Lohmann

Publikováno v: Cardiovascular Research. 53:852-861

Objective: The natriuretic peptides (NPs), atrial (ANP), B-type (BNP), and C-type (CNP) natriuretic peptides as well as their respective receptor-guanylyl cyclases (GC-A for ANP and BNP, and GC-B for CNP) are expressed in the heart. However, the loca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe73bf41e2e3e1407714ae72207d443
https://doi.org/10.1016/s0008-6363(01)00543-0

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A novel rolling-circle-replicating plasmid from Pseudomonas putida P8: molecular characterization and use as vector The EMBL and GenBank accession number for the nucleotide sequence of pPP8–1 is AJ289784

Autor: Angelika von Wallbrunn, Friedhelm Meinhardt, Rita Holtwick, Heribert Keweloh

Publikováno v: Microbiology. 147:337-344

In Pseudomonas putida P8, three cryptic circular plasmids were detected, i.e. pPP8-1 (2.5 kbp), pPP8-2 (42 kbp) and pPP8-3 (approximately 100 kbp). Cloning and complete sequencing of pPP8-1 revealed a 2534 bp element harbouring four open reading fram

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4deafeb6421e89f63923d5337b94549b
https://doi.org/10.1099/00221287-147-2-337

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cis/trans Isomerase of Unsaturated Fatty Acids of Pseudomonas putida P8: Evidence for a Heme Protein of the Cytochrome c Type

Autor: Friedhelm Meinhardt, Rita Holtwick, Heribert Keweloh

Publikováno v: Applied and Environmental Microbiology. 65:2644-2649

From a pool of 600 temperature-sensitive transposon mutants of Pseudomonas putida P8, 1 strain was isolated that carries a mini-Tn 5 insertion within the cytochrome c operon. As a result, genes involved in the attachment of heme to cytochrome c -type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b4c1994ddd0bc3ea9b025ca497e459
https://doi.org/10.1128/aem.65.6.2644-2649.1999

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cis-trans isomerization of unsaturated fatty acids: cloning and sequencing of the cti gene from Pseudomonas putida P8

Autor: Rita Holtwick, Friedhelm Meinhardt, Heribert Keweloh

Publikováno v: Applied and Environmental Microbiology. 63:4292-4297

Transposon mutants of Pseudomonas putida P8 were generated by applying a mini-Tn5 mutagenesis system. The mutants obtained were checked for their ability to tolerate increased temperatures and elevated phenol concentrations. Approximately 5,800 trans

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https://doi.org/10.1128/aem.63.11.4292-4297.1997

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