Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Rita, Padányi"'
Autor:
Blanka Berta, Hedvig Tordai, Gergely L. Lukács, Béla Papp, Ágnes Enyedi, Rita Padányi, Tamás Hegedűs
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The clinical management of severe COVID-19 cases is not yet well resolved. Therefore, it is important to identify and characterize cell signaling pathways involved in virus pathogenesis that can be targeted therapeutically. Envelope (E) prot
Externí odkaz:
https://doaj.org/article/b1a35e72b7564ce294fa597e41590c61
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Single amino acid substitutions can profoundly affect protein folding, dynamics, and function. The ability to discern between benign and pathogenic substitutions is pivotal for therapeutic interventions and research directions. Given the lim
Externí odkaz:
https://doaj.org/article/ebdfafeb85e240558d1f013b266f21f4
Autor:
Rita Padányi, Bianka Farkas, Hedvig Tordai, Bálint Kiss, Helmut Grubmüller, Naoto Soya, Gergely L. Lukács, Miklós Kellermayer, Tamás Hegedűs
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2587-2599 (2022)
Cystic fibrosis (CF) is a frequent genetic disease in Caucasians that is caused by the deletion of F508 (ΔF508) in the nucleotide binding domain 1 (NBD1) of the CF transmembrane conductance regulator (CFTR). The ΔF508 compromises the folding energe
Externí odkaz:
https://doaj.org/article/f824232d22a54693a0c1dca0363f6c83
Autor:
Karolina Varga, Anna Hollósi, Katalin Pászty, Luca Hegedűs, Gergely Szakács, József Tímár, Béla Papp, Ágnes Enyedi, Rita Padányi
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-17 (2018)
Abstract Background Remodeling of Ca2+ signaling is an important step in cancer progression, and altered expression of members of the Ca2+ signaling toolkit including the plasma membrane Ca2+ ATPases (PMCA proteins encoded by ATP2B genes) is common i
Externí odkaz:
https://doaj.org/article/874151123680404c81771e4031fd706d
Autor:
Luca Hegedüs, Rita Padányi, Judit Molnár, Katalin Pászty, Karolina Varga, István Kenessey, Eszter Sárközy, Matthias Wolf, Michael Grusch, Zoltán Hegyi, László Homolya, Clemens Aigner, Tamás Garay, Balázs Hegedüs, József Tímár, Enikö Kállay, Ágnes Enyedi
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca2
Externí odkaz:
https://doaj.org/article/5a9a973d5cf6496382250ee896690605
Autor:
Silvio C. E. Tosatto, Zsuzsanna Dosztányi, Hedvig Tordai, Rita Padányi, Tamás Hegedűs, Georgina Csizmadia, Gábor Erdős
Publikováno v:
Nucleic Acids Research
Protein and lipid membrane interactions play fundamental roles in a large number of cellular processes (e.g. signalling, vesicle trafficking, or viral invasion). A growing number of examples indicate that such interactions can also rely on intrinsica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0982728896dbc59fd05f3b13e7fc9a43
http://europepmc.org/articles/PMC7778998
http://europepmc.org/articles/PMC7778998
Autor:
Hedvig Tordai, Rita Padányi, Bianka Farkas, Bálint Kiss, Helmut Grubmüller, Miklós S.Z. Kellermayer, Gergely L. Lukacs, Tamás Hegedus, Naoto Soya
Cystic fibrosis is most frequently caused by the deletion of F508 (ΔF508) in CFTR’s nucleotide binding domain 1 (NBD1), compromising CFTR folding, stability and domain assembly. The limitation of developing a successful therapy is due to the lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4fe9ae08d5af612f9a7275a3df65ce1
https://doi.org/10.1101/2021.08.20.457065
https://doi.org/10.1101/2021.08.20.457065
Autor:
Rita Padányi, János Gera, Tamás Hegedűs, Attila Tordai, Gábor Paragi, Hedvig Tordai, Bianka Farkas
Publikováno v:
Cellular and Molecular Life Sciences
Cystic fibrosis (CF), a lethal monogenic disease, is caused by pathogenic variants of the CFTR chloride channel. The majority of CF mutations affect protein folding and stability leading overall to diminished apical anion conductance of epithelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0550d80f1dc603f7973f6eaf7b6a71fd
https://doi.org/10.1007/s00018-019-03211-4
https://doi.org/10.1007/s00018-019-03211-4
Autor:
Gergely Szakács, Ágnes Enyedi, Rita Padányi, Karolina Varga, József Tímár, Luca Hegedűs, Béla Papp, Anna Hollósi, Katalin Pászty
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-17 (2018)
BMC Cancer
BMC Cancer
Background Remodeling of Ca2+ signaling is an important step in cancer progression, and altered expression of members of the Ca2+ signaling toolkit including the plasma membrane Ca2+ ATPases (PMCA proteins encoded by ATP2B genes) is common in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e317d4c2f421b93f0e7c68dc34e74169
http://link.springer.com/article/10.1186/s12885-018-4945-x
http://link.springer.com/article/10.1186/s12885-018-4945-x
Autor:
Luca, Hegedűs, Boglárka, Zámbó, Katalin, Pászty, Rita, Padányi, Karolina, Varga, John T, Penniston, Ágnes, Enyedi
Publikováno v:
Advances in experimental medicine and biology. 1131
Plasma membrane Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d182b5ea151e7e71ff2c6f0668aa9a0
https://pubmed.ncbi.nlm.nih.gov/31646508
https://pubmed.ncbi.nlm.nih.gov/31646508