Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Rita, Nano"'
Autor:
Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114047- (2024)
Summary: Using 13C6 glucose labeling coupled to gas chromatography-mass spectrometry and 2D 1H-13C heteronuclear single quantum coherence NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning β cell functi
Externí odkaz:
https://doaj.org/article/2e924f2360b54e9dbc6f6da13e566a04
Allo Beta Cell transplantation: specific features, unanswered questions, and immunological challenge
Autor:
Rossana Caldara, Valentina Tomajer, Paolo Monti, Valeria Sordi, Antonio Citro, Raniero Chimienti, Chiara Gremizzi, Davide Catarinella, Stefano Tentori, Vera Paloschi, Raffella Melzi, Alessia Mercalli, Rita Nano, Paola Magistretti, Stefano Partelli, Lorenzo Piemonti
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type 1 diabetes (T1D) presents a persistent medical challenge, demanding innovative strategies for sustained glycemic control and enhanced patient well-being. Beta cells are specialized cells in the pancreas that produce insulin, a hormone that regul
Externí odkaz:
https://doaj.org/article/1fd182f972064ef3a90189fdae70ac20
Autor:
Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Firas, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L., Gribble, Fiona M., Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick
Publikováno v:
In Molecular Metabolism December 2020 42
Autor:
Daniela Nasteska, Nicholas H. F. Fine, Fiona B. Ashford, Federica Cuozzo, Katrina Viloria, Gabrielle Smith, Aisha Dahir, Peter W. J. Dawson, Yu-Chiang Lai, Aimée Bastidas-Ponce, Mostafa Bakhti, Guy A. Rutter, Remi Fiancette, Rita Nano, Lorenzo Piemonti, Heiko Lickert, Qiao Zhou, Ildem Akerman, David J. Hodson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Beta cell subpopulations with low expression in PDX1, MAFA, and insulin might contribute to islet function and insulin release. Here the authors show that altering the proportion of PDX1LOW MAFALOW to PDX1HIGH MAFAHIGH cells impairs islet function.
Externí odkaz:
https://doaj.org/article/cf504598ffd644018cbb1c9c1fc2bf2c
Autor:
Iacopo Gesmundo, Barbara Pardini, Eleonora Gargantini, Giacomo Gamba, Giovanni Birolo, Alessandro Fanciulli, Dana Banfi, Noemi Congiusta, Enrica Favaro, Maria Chiara Deregibus, Gabriele Togliatto, Gaia Zocaro, Maria Felice Brizzi, Raul M. Luque, Justo P. Castaño, Maria Alessandra Bocchiotti, Simone Arolfo, Stefania Bruno, Rita Nano, Mario Morino, Lorenzo Piemonti, Huy Ong, Giuseppe Matullo, Juan M. Falcón-Pérez, Ezio Ghigo, Giovanni Camussi, Riccarda Granata
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other metabolic organs, and an altered biological cargo has been observed in EVs from human obese adipose tissue (AT). Yet, the role of adipocyte-derived EVs in pancr
Externí odkaz:
https://doaj.org/article/6e988061edec4dbea6738ab3cdae512b
Autor:
Andrea Laurenzi, Amelia Caretto, Chiara Molinari, Elena Bazzigaluppi, Cristina Brigatti, Ilaria Marzinotto, Alessia Mercalli, Raffaella Melzi, Rita Nano, Cristina Tresoldi, Giovanni Landoni, Fabio Ciceri, Vito Lampasona, Marina Scavini, Lorenzo Piemonti
Publikováno v:
Biology, Vol 10, Iss 8, p 754 (2021)
Aim. The aim of the current study was to compare clinical characteristics, laboratory findings, and major outcomes of patients hospitalized for COVID-19 pneumonia with COVID-associated hyperglycaemia or pre-existing diabetes. Methods. A cohort of 176
Externí odkaz:
https://doaj.org/article/26ceefe2726b44e1ae7523895b3a0b9e
Autor:
Daniela Nasteska, Nicholas H. F. Fine, Fiona B. Ashford, Federica Cuozzo, Katrina Viloria, Gabrielle Smith, Aisha Dahir, Peter W. J. Dawson, Yu-Chiang Lai, Aimée Bastidas-Ponce, Mostafa Bakhti, Guy A. Rutter, Remi Fiancette, Rita Nano, Lorenzo Piemonti, Heiko Lickert, Qiao Zhou, Ildem Akerman, David J. Hodson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/babcfb71b6f54a778b28993243b49eed
Autor:
Federica Cuozzo, Katrina Viloria, Daniela Nasteska, Zicong Jiao, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo Ceresa, Leanne Hodson, Amy Davies, Guy Rutter, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David Hodson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80325f585ad3c023f23f221e11be6180
https://doi.org/10.2139/ssrn.4398981
https://doi.org/10.2139/ssrn.4398981
Autor:
Federica Cuozzo, Daniela Nasteska, Zicong Jiao, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Jennie Roberts, Gareth G. Lavery, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson
Using13C6glucose labeling coupled to GC-MS and 2D1H-13C HSQC NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning steady state insulin release and β cell function. In both mouse and human islets, the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77e548212058b36324c91ca36307055
https://doi.org/10.1101/2022.12.21.521364
https://doi.org/10.1101/2022.12.21.521364
Autor:
Silvia Pellegrini, Fabio Manenti, Raniero Chimienti, Rita Nano, Linda Ottoboni, Francesca Ruffini, Gianvito Martino, Philippe Ravassard, Lorenzo Piemonti, Valeria Sordi
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Background: New sources of insulin-secreting cells are strongly in demand for treatment of diabetes. Induced pluripotent stem cells (iPSCs) have the potential to generate insulin-producing cells (iβ). However, the gene expression profile and secreto
Externí odkaz:
https://doaj.org/article/f9beaf41f0f04aa8bdd55f4c5882fb14