Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Risto Kostiainen"'
Autor:
Virpi Talman, Jaakko Teppo, Päivi Pöhö, Parisa Movahedi, Anu Vaikkinen, S. Tuuli Karhu, Kajetan Trošt, Tommi Suvitaival, Jukka Heikkonen, Tapio Pahikkala, Tapio Kotiaho, Risto Kostiainen, Markku Varjosalo, Heikki Ruskoaho
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 20 (2018)
Background The molecular mechanisms mediating postnatal loss of cardiac regeneration in mammals are not fully understood. We aimed to provide an integrated resource of mRNA, protein, and metabolite changes in the neonatal heart for identification of
Externí odkaz:
https://doaj.org/article/9482c6aaa55e4ff6836035f853b4f626
Autor:
Linda Ahonen, Sirkku Jäntti, Tommi Suvitaival, Simone Theilade, Claudia Risz, Risto Kostiainen, Peter Rossing, Matej Orešič, Tuulia Hyötyläinen
Publikováno v:
Metabolites, Vol 9, Iss 9, p 184 (2019)
Several small molecule biomarkers have been reported in the literature for prediction and diagnosis of (pre)diabetes, its co-morbidities, and complications. Here, we report the development and validation of a novel, quantitative method for the determ
Externí odkaz:
https://doaj.org/article/527d204177f6488eacb9c61a10b270eb
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133904 (2015)
Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from peripheral sources. In the current study, permeation
Externí odkaz:
https://doaj.org/article/3f2b0e7d07104894b4721d986c528ca3
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 663-672 (2001)
Electrospray ionization-mass spectrometry (ESI-MS) is a very promising tool for the analysis of phospholipid compositions, but is hampered by the fact that not all molecular species are detected with equal efficiency. We studied this and other issues
Externí odkaz:
https://doaj.org/article/e496aa9c902e44fdbf649703397fda93
Autor:
Tina Suominen, Päivi Uutela, Raimo A Ketola, Jonas Bergquist, Lars Hillered, Moshe Finel, Hongbo Zhang, Aki Laakso, Risto Kostiainen
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68007 (2013)
An UPLC-MS/MS method was developed for the determination of serotonin (5-HT), dopamine (DA), their phase I metabolites 5-HIAA, DOPAC and HVA, and their sulfate and glucuronide conjugates in human brain microdialysis samples obtained from two patients
Externí odkaz:
https://doaj.org/article/7902cbc36bd84fa68c5c70db7f5f89ce
Autor:
Jaroslav Pól, Veronika Vidová, Tuulia Hyötyläinen, Michael Volný, Petr Novák, Martin Strohalm, Risto Kostiainen, Vladimír Havlíček, Susanne K Wiedmer, Juha M Holopainen
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19441 (2011)
Knowledge of the spatial distribution of lipids in the intraocular lens is important for understanding the physiology and biochemistry of this unique tissue and for gaining a better insight into the mechanisms underlying diseases of the lens. Followi
Externí odkaz:
https://doaj.org/article/bdaa163ea7d749969264782f72ba9db3
Publikováno v:
Journal of Proteome Research.
In this study, we show that infrared laser ablation atmospheric pressure photoionization mass spectrometry (LAAPPI-MS) imaging with 70 μm lateral resolution allows for the analysis of Arabidopsis thaliana (A. thaliana) leaf substructures ranging fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8c32af3fbe95fd1aa31f896926c724
http://hdl.handle.net/10138/339092
http://hdl.handle.net/10138/339092
Publikováno v:
Journal of chromatography. A. 1656
We developed a new multiplexed reversed phase liquid chromatography-high resolution tandem mass spectrometric (LC-MS/MS) method. The method is based on isobaric labeling with a tandem mass tag (TMT10-plex) and stable isotope-labeled internal standard
Publikováno v:
Journal of the American Society for Mass Spectrometry
In this study, we show that infrared laser ablation atmospheric pressure photoionization mass spectrometry (LAAPPI-MS) imaging with 70 μm lateral resolution allows for the analysis of Arabidopsis thaliana (A. thaliana) leaf substructures ranging fro