Výsledky vyhledávání - "Risto Johansson"

Thymidine Kinase Gene Therapy for Human Malignant Glioma, Using Replication-Deficient Retroviruses or Adenoviruses

Autor: Heleena Hurskainen, Paula Puranen, Marita Turunen, Maija Kossila, Anu-Maaria Sandmair, Ritva Vanninen, Sami Loimas, Seppo Ylä-Herttuala, Pauliina Lehtolainen, Kristiina Tyynelä, M. Puranen, Leo Paljärvi, Risto Johansson, Arto Immonen, Matti Vapalahti

Publikováno v: Human Gene Therapy. 11:2197-2205

Herpes simplex virus thymidine kinase (HSV tk) gene therapy combined with ganciclovir (GCV) medication is a potential new method for the treatment of malignant glioma. We have used both retrovirus-packaging cells (PA317/tk) and adenoviruses (Adv/tk)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed5ff4a7df650aa58d6af147d9e0bc3
https://doi.org/10.1089/104303400750035726

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Reduced expression of CD44v3 variant isoform is associated with unfavorable outcome in non–small cell lung carcinoma

Autor: Pasi Hirvikoski, Risto Johansson, Risto Pirinen, Jari Kellokoski, Jan Böhm, Markku M. T. Viren, K I Moisio, Veli-Matti Kosma, Sinikka Hollmen

Publikováno v: Human Pathology. 31:1088-1095

The expression of CD44 standard form (CD44s) and variant isoforms v3 and v6 was analyzed in 233 resected non-small cell lung carcinoma (NSCLC) specimens by immunohistochemistry (IHC), and the mRNA status of CD44v3 and CD44v6 in a cohort of samples wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9b3aaef8ee13fae14e3c69614a4576
https://doi.org/10.1053/hupa.2000.16277

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Enhanced apoptosis correlates with poor survival in patients with laryngeal cancer but not with cell proliferation, bcl-2 or p53 expression

Autor: Risto Johansson, Pirjo Halonen, Jukka Virtaniemi, Veli-Matti Kosma, L. Salmi, Risto Pirinen, Eero J. Kumpulainen, Pasi Hirvikoski

Publikováno v: European Journal of Cancer. 35:231-237

The purpose of the current study was to analyse apoptosis and bcl-2 expression in laryngeal squamous cell carcinoma (SCC) with special reference to their prognostic significance, correlation with the clinical and pathological characteristics as well

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e50308282d14ad97d79a8716ef8717
https://doi.org/10.1016/s0959-8049(98)00347-5

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Hypermethylation of calcitonin gene regulatory sequences in human breast cancer as revealed by genomic sequencing

Autor: Mikko Hiltunen, Sanna Myöhänen, Risto Johansson, Juhani Jänne, Jarmo Wahlfors, Matti Eskelinen, Mika Hakkarainen

Publikováno v: International Journal of Cancer. 69:471-474

DNA methylation has been studied intensively during the past years in order to elucidate its role in the regulation of gene expression, gene imprinting and cancer progression. Earlier studies have shown that a general genomic under-methylation is ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58466251692af3b3d3d586dee2bff79
https://doi.org/10.1002/(sici)1097-0215(19961220)69:6<471::aid-ijc9>3.0.co

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Merkel cell carcinoma of the auricle

Autor: Risto Johansson, Veli-Matti Kosma, Pasi Hirvikoski, Matti Pukkila, Eero J. Kumpulainen, Jukka Virtaniemi

Publikováno v: European Archives of Oto-Rhino-Laryngology. 257:558-560

Merkel cell carcinoma is a rare, although increasingly recognized, malignant tumor of the skin. The most common site of occurrence is the head and neck (50%). Only five cases of this tumor on the auricle have been reported previously. We present a fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fea0fe93bc42309971e68a3bfbdedd
https://doi.org/10.1007/s004050000291

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Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer

Autor: Tero, Leinonen, Risto, Pirinen, Jan, Böhm, Risto, Johansson, Veli-Matti, Kosma

Publikováno v: Histology and histopathology. 23(6)

The purpose of this study was to analyse the expression of matrix metalloproteinase-2 (MMP-2) and its extracellular matrix metalloproteinase inducer (EMMPRIN) in non-small cell lung cancer (NSCLC), and to evaluate their significance to predict tumour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::470e740eed14514ed5edd1b264bbb0f3
https://pubmed.ncbi.nlm.nih.gov/18366007

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Expression of matrix metalloproteinases 7 and 9 in non-small cell lung cancer. Relation to clinicopathological factors, beta-catenin and prognosis

Autor: Tero, Leinonen, Risto, Pirinen, Jan, Böhm, Risto, Johansson, Kirsi, Ropponen, Veli-Matti, Kosma

Publikováno v: Lung cancer (Amsterdam, Netherlands). 51(3)

Matrix metalloproteinases (MMPs) have been shown to have a significant role in determining cancer cell behaviour. The present study was undertaken to analyze the expression and prognostic value of MMP-7 and MMP-9 in non-small cell lung cancer (NSCLC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b94b8540c0a93532de689c7ea5be36f
https://pubmed.ncbi.nlm.nih.gov/16423426

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