CRISPR-Cas knockout of miR21 reduces glioma growth.

Autor: Nieland L; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA.; Department of Neurosurgery, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., van Solinge TS; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA., Cheah PS; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA.; Department of Human Anatomy, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang 43400, Malaysia., Morsett LM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., El Khoury J; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Rissman JI; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02115, USA., Kleinstiver BP; Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, MA 02115, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02114, USA., Broekman MLD; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA.; Department of Neurosurgery, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.; Department of Neurosurgery, Haaglanden Medical Center, 2512 VA The Hague, the Netherlands., Breakefield XO; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA., Abels ER; Departments of Neurology and Radiology, Massachusetts General Hospital, Neuroscience Program, Harvard Medical School, Boston, MA 02129, USA.; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.

Publikováno v: Molecular therapy oncolytics [Mol Ther Oncolytics] 2022 Apr 06; Vol. 25, pp. 121-136. Date of Electronic Publication: 2022 Apr 06 (Print Publication: 2022).