Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Rissiek A"'
Autor:
Thomas Eden, Alessa Z. Schaffrath, Janusz Wesolowski, Tobias Stähler, Natalie Tode, Nathalie Richter, Waldemar Schäfer, Julia Hambach, Irm Hermans-Borgmeyer, Jannis Woens, Camille M. Le Gall, Sabrina Wendler, Christian Linke-Winnebeck, Martina Stobbe, Iwona Budnicki, Amelie Wanney, Yannic Heitz, Lena Schimmelpfennig, Laura Schweitzer, Dennis Zimmer, Erik Stahl, Fabienne Seyfried, Anna J. Gebhardt, Lynn Dieckow, Kristoffer Riecken, Boris Fehse, Peter Bannas, Tim Magnus, Martijn Verdoes, Carl G. Figdor, Klaus F. Hartlepp, Hubertus Schleer, Jonas Füner, Nicola M. Tomas, Friedrich Haag, Björn Rissiek, Anna M. Mann, Stephan Menzel, Friedrich Koch-Nolte
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Due to their exceptional solubility and stability, nanobodies have emerged as powerful building blocks for research tools and therapeutics. However, their generation in llamas is cumbersome and costly. Here, by inserting an engineered llama
Externí odkaz:
https://doaj.org/article/06c0fed6be0b4da1ae092b68397ac332
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Microglia play a crucial role in maintaining homeostasis of the central nervous system and they are actively involved in shaping the brain’s inflammatory response to stress. Among the multitude of involved molecules, purinergic receptors and enzyme
Externí odkaz:
https://doaj.org/article/30154e31ac5e447c84e47ea15af4b30f
Autor:
Juan Sierra-Marquez, Lena Schaller, Lukas Sassenbach, Antonio Ramírez-Fernández, Philipp Alt, Björn Rissiek, Béla Zimmer, Johann Schredelseker, Julia Hector, Tobias Stähler, Friedrich Koch-Nolte, Claudia A. Staab-Weijnitz, Alexander Dietrich, Robin Kopp, Annette Nicke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionP2X receptors are a family of homo- and heterotrimeric cation channels gated by extracellular ATP. The P2X4 and P2X7 subunits show overlapping expression patterns and have been involved in similar physiological processes, such as pain and
Externí odkaz:
https://doaj.org/article/b55a6bb7bcc24c3691c0c6357b0bf403
Autor:
Stephan Menzel, Yinghui Duan, Julia Hambach, Birte Albrecht, Dorte Wendt-Cousin, Riekje Winzer, Eva Tolosa, Anne Rissiek, Andreas H. Guse, Friedrich Haag, Tim Magnus, Friedrich Koch-Nolte, Björn Rissiek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD39 is the major enzyme controlling the levels of extracellular adenosine triphosphate (ATP) via the stepwise hydrolysis of ATP to adenosine diphosphate (ADP) and adenosine monophosphate (AMP). As extracellular ATP is a strong promoter of inflammati
Externí odkaz:
https://doaj.org/article/ede936c25e8b4acd80c5bcc8d2044e79
Autor:
Durga Praveen Meka, Melanie Richter, Tabitha Rücker, Hannah Voss, Anne Rissiek, Christoph Krisp, Nisha Hemandhar Kumar, Birgit Schwanke, Eugenio F. Fornasiero, Hartmut Schlüter, Froylan Calderon de Anda
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102793- (2024)
Summary: Here, we present a protocol for differential multi-omic analyses of distinct cell types in the developing mouse cerebral cortex. We describe steps for in utero electroporation, subsequent flow-cytometry-based isolation of developing mouse co
Externí odkaz:
https://doaj.org/article/eee56e1f1edb44948be54c5032d54001
Autor:
Valerie J. Brock, Niels Christian Lory, Franziska Möckl, Melina Birus, Tobias Stähler, Lena-Marie Woelk, Michelle Jaeckstein, Joerg Heeren, Friedrich Koch-Nolte, Björn Rissiek, Hans-Willi Mittrücker, Andreas H. Guse, René Werner, Björn-Philipp Diercks
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD8+ T cells are a crucial part of the adaptive immune system, responsible for combating intracellular pathogens and tumor cells. The initial activation of T cells involves the formation of highly dynamic Ca2+ microdomains. Recently, purinergic signa
Externí odkaz:
https://doaj.org/article/a2847c04e466468e97ea1424969ec6f1
Akademický článek
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Autor:
Alejandro Montilla, Alazne Zabala, Marco Er-Lukowiak, Björn Rissiek, Tim Magnus, Noelia Rodriguez-Iglesias, Amanda Sierra, Carlos Matute, María Domercq
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract In multiple sclerosis and the experimental autoimmune encephalomyelitis (EAE) model, both resident microglia and infiltrating macrophages contribute to demyelination as well as spontaneous remyelination. Nevertheless, the specific roles of m
Externí odkaz:
https://doaj.org/article/6a0c15c469b04ffda3b3e6378ecc1f7d
Autor:
Maximilian Wilmes, Carolina Pinto Espinoza, Peter Ludewig, Joschi Stabernack, Arthur Liesz, Annette Nicke, Mathias Gelderblom, Christian Gerloff, Simonetta Falzoni, Eva Tolosa, Francesco Di Virgilio, Björn Rissiek, Nikolaus Plesnilla, Friedrich Koch-Nolte, Tim Magnus
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Previous studies have demonstrated that purinergic receptors could be therapeutic targets to modulate the inflammatory response in multiple models of brain diseases. However, tools for the selective and efficient targeting of thes
Externí odkaz:
https://doaj.org/article/42a72dde94804cbaafa23cc1ebad1ef5
Akademický článek
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