Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Risaku Fukumoto"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90448 (2014)
Severe hematopoietic loss is one of the major therapeutic targets after radiation-combined injury (CI), a kind of injury resulting from radiation exposure combined with other traumas. In this study, we tested the use of ciprofloxacin (CIP) as a treat
Externí odkaz:
https://doaj.org/article/fd26ead0e6894359bea9b0cb92d44b02
Autor:
Risaku Fukumoto, Lynnette H Cary, Nikolai V Gorbunov, Eric D Lombardini, Thomas B Elliott, Juliann G Kiang
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58389 (2013)
Radiation combined injury (CI) is a radiation injury (RI) combined with other types of injury, which generally leads to greater mortality than RI alone. A spectrum of specific, time-dependent pathophysiological changes is associated with CI. Of these
Externí odkaz:
https://doaj.org/article/d04b51b9dd4e453cbf173b32ea5782aa
Autor:
Michael J Daly, Elena K Gaidamakova, Vera Y Matrosova, Juliann G Kiang, Risaku Fukumoto, Duck-Yeon Lee, Nancy B Wehr, Gabriela A Viteri, Barbara S Berlett, Rodney L Levine
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12570 (2010)
For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance, manganese accumulation, and protein protection. We show that ult
Externí odkaz:
https://doaj.org/article/1c254163d01c4fb49c698ee02e183923
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 9, Iss 5, Pp 447-449
Externí odkaz:
https://doaj.org/article/340f2c591db84021825637a31b69569d
Publikováno v:
Molecular and Cellular Biochemistry. 393:133-143
Ionizing radiation increases cell mortality in a dose-dependent manner. Increases in DNA double strand breaks, γ-H2AX, p53 phophorylation, and protein levels of p53 and Bax also occur. We investigated the ability of ciprofloxacin (CIP), a widely pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db116b52baca750692d4d59837557181
https://doi.org/10.1007/s11010-014-2053-z
https://doi.org/10.1007/s11010-014-2053-z
Autor:
Cynthia A. Pise-Masison, Dustin Edwards, Genoveffa Franchini, Robyn Washington Parks, Risaku Fukumoto, Luiz Carlos Junior Alcantara, Bernardo Galvão-Castro, Maria Fernanda de Castro-Amarante
Publikováno v:
Journal of Virology. 88:2319-2322
The orf-I gene of human T-cell leukemia type 1 (HTLV-1) encodes p8 and p12 and has a conserved cysteine at position 39. p8 and p12 form disulfide-linked dimers, and only the monomeric forms of p8 and p12 are palmitoylated. Mutation of cysteine 39 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af74631311baa2b133c76bb9f3ec56af
https://doi.org/10.1128/jvi.03444-13
https://doi.org/10.1128/jvi.03444-13
Autor:
Risaku Fukumoto
Publikováno v:
Cancer Sci
It has been more than 30 years since the discovery of human T‐lymphotropic virus type 1 (HTLV‐1), the first human retrovirus identified. Human T‐lymphotropic virus type 1 infects 15–20 million people worldwide causing two major diseases: adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8751ce1968638690f8b743762986bb97
https://doi.org/10.1111/cas.12190
https://doi.org/10.1111/cas.12190
Autor:
Risaku Fukumoto
Publikováno v:
Military Medical Research
Acute radiation syndrome affects military personnel and civilians following the uncontrolled dispersal of radiation, such as that caused by detonation of nuclear devices and inappropriate medical treatments. Therefore, there is a growing need for med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb542fafe5724e7f2fc4b3f1d3db0b1
https://doi.org/10.1186/s40779-016-0086-1
https://doi.org/10.1186/s40779-016-0086-1
Autor:
Marcia Bellon, Valentina Cecchinato, Genoveffa Franchini, Risaku Fukumoto, Uma Sinha-Datta, Cynthia A. Pise-Masison, Robyn Washington Parks, Vibeke Andresen, Christophe Nicot, Valerio W. Valeri
Publikováno v:
Blood. 118:1549-1559
Disease development in human T-cell leukemia virus type 1 (HTLV-1)–infected individuals is positively correlated with the level of integrated viral DNA in T cells. HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85caff135921e88c1e9891d57973cc4c
https://doi.org/10.1182/blood-2010-06-293340
https://doi.org/10.1182/blood-2010-06-293340
Autor:
Miroslav Dundr, Christophe Nicot, Valerio W. Valeri, Genoveffa Franchini, Risaku Fukumoto, Anthony Adams, Lawrence E. Samelson
Publikováno v:
Journal of Virology. 81:9088-9099
The p12 I protein of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) is a small oncoprotein that increases calcium release following protein kinase C activation by phorbol myristate acetate, and importantly, this effect is linker for activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1891d3af62754e81f95a4d89d823b0
https://doi.org/10.1128/jvi.02703-06
https://doi.org/10.1128/jvi.02703-06