Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Risa Shishido"'
Autor:
Atsuko Nagaoka, Mizuki Hino, Ryuta Izumi, Risa Shishido, Miki Ishibashi, Masataka Hatano, Makoto Sainouchi, Akiyoshi Kakita, Hiroaki Tomita, Yasuto Kunii
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 2, Pp 399-409 (2024)
Abstract Aim Postmortem brain research is necessary for elucidating the pathology of schizophrenia; an increasing number of studies require a combination of suitable tissue samples preserved at multiple brain banks. In this study, we examined whether
Externí odkaz:
https://doaj.org/article/e19f62b72bd64341a982eb3f469f2bd4
Autor:
Mizuki Hino, Yasuto Kunii, Risa Shishido, Atsuko Nagaoka, Junya Matsumoto, Hiroyasu Akatsu, Yoshio Hashizume, Hideki Hayashi, Akiyoshi Kakita, Hiroaki Tomita, Hirooki Yabe
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 121-128 (2024)
Abstract Aim The etiology of bipolar disorder (BD) remains unknown; however, lipid abnormalities in BD have received increasing attention in recent years. In this study, we examined the expression levels of enzyme proteins associated with the metabol
Externí odkaz:
https://doaj.org/article/6e606ffe19e94b8daa0f3078d123b804
Autor:
Kazusa Miyahara, Mizuki Hino, Risa Shishido, Atsuko Nagaoka, Ryuta Izumi, Hideki Hayashi, Akiyoshi Kakita, Hirooki Yabe, Hiroaki Tomita, Yasuto Kunii
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Schizophrenia is a multifactorial disorder, the genetic architecture of which remains unclear. Although many studies have examined the etiology of schizophrenia, the gene sets that contribute to its symptoms have not been fully investigated.
Externí odkaz:
https://doaj.org/article/77eff89cc70b4749b806c704fa3ab4c3
Autor:
Risa Shishido, Yasuto Kunii, Mizuki Hino, Ryuta Izumi, Atsuko Nagaoka, Hideki Hayashi, Akiyoshi Kakita, Hiroaki Tomita, Hirooki Yabe
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundSchizophrenia (SZ) is a disorder diagnosed by specific symptoms and duration and is highly heterogeneous, clinically and pathologically. Although there are an increasing number of studies on the association between genetic and environmental
Externí odkaz:
https://doaj.org/article/4f4d492250b14b828594cd804814bc89
Autor:
Kazusa Miyahara, Mizuki Hino, Zhiqian Yu, Chiaki Ono, Atsuko Nagaoka, Masataka Hatano, Risa Shishido, Hirooki Yabe, Hiroaki Tomita, Yasuto Kunii
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundEvaluating and controlling confounders are necessary when investigating molecular pathogenesis using human postmortem brain tissue. Particularly, tissue pH and RNA integrity number (RIN) are valuable indicators for controlling confounders.
Externí odkaz:
https://doaj.org/article/957c8a4e574a4db4afe10681d1ff595e
Autor:
Yasuto Kunii, Junya Matsumoto, Ryuta Izumi, Atsuko Nagaoka, Mizuki Hino, Risa Shishido, Makoto Sainouchi, Hiroyasu Akatsu, Yoshio Hashizume, Akiyoshi Kakita, Hirooki Yabe
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8280 (2021)
Phosphoinositides (PIs) play important roles in the structure and function of the brain. Associations between PIs and the pathophysiology of schizophrenia have been studied. However, the significance of the PI metabolic pathway in the pathology of sc
Externí odkaz:
https://doaj.org/article/1f36905c42e24288910a07db9b2dd52c
Autor:
Ryuta Izumi, Risa Shishido, Hirooki Yabe, Mikio Hoshino, Yasuto Kunii, Akiyoshi Kakita, Atsuko Nagaoka, Mizuki Hino
Publikováno v:
Neuroscience Research. 175:73-81
The mechanistic target of rapamycin (mTOR)-signaling and dihydropyrimidinase-like 2 (DPYSL2), which are increasingly gaining attention as potential therapeutic targets for schizophrenia, are connected via Cap-dependent translation of the 5'TOP motif.
Autor:
Yuriko Iwakura, Ryoka Kawahara-Miki, Satoshi Kida, Hidekazu Sotoyama, Ramil Gabdulkhaev, Hitoshi Takahashi, Yasuto Kunii, Mizuki Hino, Atsuko Nagaoka, Ryuta Izumi, Risa Shishido, Toshiyuki Someya, Hirooki Yabe, Akiyoshi Kakita, Hiroyuki Nawa
Publikováno v:
Neurochemical research. 47(9)
The family of epidermal growth factor (EGF) including neuregulin-1 are implicated in the neuropathology of schizophrenia. We established a rat model of schizophrenia by exposing perinatal rats to EGF and reported that the auditory pathophysiological
Autor:
Akiyoshi Kakita, Ryuta Izumi, Yasuto Kunii, Makoto Sainouchi, Junya Matsumoto, Yoshio Hashizume, Risa Shishido, Hirooki Yabe, Atsuko Nagaoka, Mizuki Hino, Hiroyasu Akatsu
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8280, p 8280 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8280, p 8280 (2021)
Phosphoinositides (PIs) play important roles in the structure and function of the brain. Associations between PIs and the pathophysiology of schizophrenia have been studied. However, the significance of the PI metabolic pathway in the pathology of sc
Autor:
Atsuko Nagaoka, Yasuto Kunii, Mizuki Hino, Ryuta Izumi, Risa Shishido, Miki Ishibashi, Masataka Hatano, Makoto Sainouchi, Akiyoshi Kakita, Hirooki Yabe
Publikováno v:
SSRN Electronic Journal.