Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Risa Nonaka"'
Autor:
Ryota Nakamura, Risa Nonaka, Genko Oyama, Takayuki Jo, Hikaru Kamo, Maierdanjiang Nuermaimaiti, Wado Akamatsu, Kei-ichi Ishikawa, Nobutaka Hattori
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundParkinson’s disease (PD) is a progressive neurodegenerative condition that primarily affects motor functions; it is caused by the loss of midbrain dopaminergic (mDA) neurons. The therapeutic effects of transplanting human-induced pluripot
Externí odkaz:
https://doaj.org/article/2825501fa70944fda796daab41750e38
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 315 (2021)
Perlecan (HSPG2), a basement membrane-type heparan sulfate proteoglycan, has been implicated in the development of aortic tissue. However, its role in the development and maintenance of the aortic wall remains unknown. Perlecan-deficient mice (Hspg2
Externí odkaz:
https://doaj.org/article/2982a35693f546609dd5a7e1847c0665
Autor:
TOSHIKI MINOBE, RISA NONAKA, TAKAHIRO SHIGA, KEI-ICHI ISHIKAWA, NOBUTAKA HATTORI, WADO AKAMATSU
Publikováno v:
Juntendo Medical Journal. 69:30-31
Autor:
Aurelien Kerever, Frederic Mercier, Risa Nonaka, Susana de Vega, Yuka Oda, Bernard Zalc, Yohei Okada, Nobutaka Hattori, Yoshihiko Yamada, Eri Arikawa-Hirasawa
Publikováno v:
Stem Cell Research, Vol 12, Iss 2, Pp 492-505 (2014)
In the adult subventricular zone (neurogenic niche), neural stem cells double-positive for two markers of subsets of neural stem cells in the adult central nervous system, glial fibrillary acidic protein and CD133, lie in proximity to fractones and t
Externí odkaz:
https://doaj.org/article/598fe44672c54cf2be0475d9af8de3f8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2322
Human-induced pluripotent stem (iPS) cells provide a powerful means for analyzing disease mechanisms and drug screening, especially for neurological diseases, considering the difficulty to obtain live pathological tissue. The midbrain dopaminergic ne
Autor:
Iwao Hasegawa, Masato Hasegawa, Yuanzhe Li, Masashi Takanashi, Hiroyo Yoshino, Manabu Funayama, Kei-Ichi Ishikawa, Montasir Elahi, Kazuko Hasegawa, Wado Akamatsu, Aya Ikeda, Yuzuru Imai, Nobutaka Hattori, Akihiro Yamaguchi, Nana Izawa, Kahori Shiba-Fukushima, Kenya Nishioka, Risa Nonaka, Hideyuki Okano, Hidemoto Saiki, Akio Mori, Masayo Morita, Tsuyoshi Inoshita, Hongrui Meng, Ayami Okuzumi
Publikováno v:
Human Molecular Genetics. 28:3895-3911
Mutations in CHCHD2 are linked to a familial, autosomal dominant form of Parkinson’s disease (PD). The gene product may regulate mitochondrial respiratory function. However, whether mitochondrial dysfunction induced by CHCHD2 mutations further yiel
Publikováno v:
Methods in Molecular Biology ISBN: 9781071614945
Human-induced pluripotent stem (iPS) cells provide a powerful means for analyzing disease mechanisms and drug screening, especially for neurological diseases, considering the difficulty to obtain live pathological tissue. The midbrain dopaminergic ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47ba7c4285a93641b5cbd9bf813115b1
https://doi.org/10.1007/978-1-0716-1495-2_8
https://doi.org/10.1007/978-1-0716-1495-2_8
Autor:
Kyohei Higashi, Toshihiko Toida, Risa Nonaka, Taihei Yamada, Aurelien Kerever, Frederic Mercier, Yusuke Yoshimura, Eri Arikawa-Hirasawa, Yuji Suzuki
Publikováno v:
Journal of Neurochemistry. 142:534-544
Adult neurogenesis in the subventricular zone of the lateral ventricle decreases with age. In the subventricular zone, the specialized extracellular matrix structures, known as fractones, contact neural stem cells and regulate neurogenesis. Fractones
Autor:
Kazuo Kaneko, I. Futami, Eri Arikawa-Hirasawa, Miguel Otero, K.L. Culley, Shinnosuke Hada, Risa Nonaka, H. Kaneko, Ryo Sadatsuki, Mayuko Kinoshita, Yoshihiko Yamada, Mary B. Goldring, Muneaki Ishijima
Publikováno v:
Journal of Orthopaedic Research. 35:837-846
We previously reported that perlecan, a heparan-sulfate proteoglycan (Hspg2), expressed in the synovium at the cartilage-synovial junction, is required for osteophyte formation in knee osteoarthritis. To examine the mechanism underlying this process,
Autor:
Kentaro Hozumi, Yoshihiko Yamada, Nobuharu Suzuki, Risa Nonaka, Motoyoshi Nomizu, Tomoko Ikeuchi, Eimi Seo, Anna Takeda, Susana de Vega, Eri Arikawa-Hirasawa
Publikováno v:
Biopolymers. 106:184-195
Despite the research done on pathological angiogenesis, there is still a need for the development of new therapies against angiogenesis-related diseases. Fibulin-7 (Fbln7) is a member of the extracellular matrix fibulin protein family. The Fbln7 C-te