Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Risa Nobuta"'
Autor:
Tadashi Nakagawa, Satoko Hattori, Risa Nobuta, Ryuichi Kimura, Makiko Nakagawa, Masaki Matsumoto, Yuko Nagasawa, Ryo Funayama, Tsuyoshi Miyakawa, Toshifumi Inada, Noriko Osumi, Keiichi I. Nakayama, Keiko Nakayama
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Haploinsufficiency of SETD5 is implicated in syndromic autism spectrum disorder (ASD), but the molecular mechanism underlying the pathological role of this protein has remained unclear. We have now shown that Setd5+/– mice manifest ASD-rel
Externí odkaz:
https://doaj.org/article/e94f71749c494d6d8151cc398653ff33
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Ribosome stalling triggers the ribosome-associated quality control (RQC) pathway, which targets collided ribosomes and leads to subunit dissociation, followed by proteasomal degradation of the nascent peptide. In yeast, RQC is triggered by Hel2-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b506d774c2e57d9f64f687031c227803
http://link.springer.com/article/10.1038/s41598-020-60241-w
http://link.springer.com/article/10.1038/s41598-020-60241-w
Publikováno v:
FEBS Letters. 593:777-787
Read-through or mutations of a stop codon resulting in translation of the 3'-UTR produce potentially toxic C-terminally extended proteins. However, quality control mechanisms for such proteins are poorly understood in mammalian cells. Here, a compreh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29519bfa243db42db4e10f8712a38071
https://doi.org/10.1002/1873-3468.13362
https://doi.org/10.1002/1873-3468.13362
Autor:
Risa Nobuta, Satoshi Hashimoto, Shizuka Nakajima, Misaki Sato, Hiroaki Imataka, Yasuhito Toriumi, Kodai Machida, Toshifumi Inada, Daiki Suto
Publikováno v:
Nucleic Acids Research
Comprehensive genome-wide analysis has revealed the presence of translational elements in the 3′ untranslated regions (UTRs) of human transcripts. However, the mechanisms by which translation is initiated in 3′ UTRs and the physiological function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b26e4fcd116a76cda04360ae5e0930e
https://pubmed.ncbi.nlm.nih.gov/32941651
https://pubmed.ncbi.nlm.nih.gov/32941651
Autor:
Yoshitaka Matsuo, Robert Buschauer, Andrea Gilmozzi, Toshifumi Inada, Roland Beckmann, Petr Tesina, Najwa Alhusaini, Jingdong Cheng, Jeff Coller, Risa Nobuta, Otto Berninghausen, Yasuko Matsuki, Ying Hsin Chen, Thomas J. Sweet, Thomas Becker, Ken Ikeuchi, Takato Sugiyama
Publikováno v:
Science
INTRODUCTION: The tightly controlled process of gene expression requires messenger RNAs (mRNAs), which represent DNA-derived blueprints for polypeptides, to be translated by the protein-producing machinery of the cell, the ribosomes. Therefore, prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbc9be3fc634be9d1735b77ca375e69
https://doi.org/10.1126/science.aay6912
https://doi.org/10.1126/science.aay6912
Autor:
Ryuichi Kimura, Keiichi I. Nakayama, Keiko Nakayama, Yuko Nagasawa, Toshifumi Inada, Masaki Matsumoto, Makiko Nakagawa, Noriko Osumi, Ryo Funayama, Satoko Hattori, Tadashi Nakagawa, Risa Nobuta, Tsuyoshi Miyakawa
Publikováno v:
iScience
iScience, Vol 23, Iss 4, Pp-(2020)
iScience, Vol 23, Iss 4, Pp-(2020)
Summary Haploinsufficiency of SETD5 is implicated in syndromic autism spectrum disorder (ASD), but the molecular mechanism underlying the pathological role of this protein has remained unclear. We have now shown that Setd5+/– mice manifest ASD-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b5017a98e3397a097cfbfcd7982ef6
http://europepmc.org/articles/PMC7160574
http://europepmc.org/articles/PMC7160574
Publikováno v:
Biochemical and biophysical research communications. 488(1)
Up-frameshift (Upf) complex facilitates the degradation of aberrant mRNAs containing a premature termination codon (PTC) and its products in yeast. Here we report that Sse1, a member of the Hsp110 family, and Hsp70 play a crucial role in Upf-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abac0f806ca90c91bdf352bf62cb479e
https://pubmed.ncbi.nlm.nih.gov/28483531
https://pubmed.ncbi.nlm.nih.gov/28483531
Autor:
Yutaka Suzuki, Shiho Makino, Risa Nobuta, Tatsuhisa Tsuboi, Tohru Yoshihisa, Reina Yamazaki, Christopher Trotta, Ken Ikeuchi, Toshifumi Inada, Ayumi Ohtaki
The tRNA splicing endonuclease (Sen) complex is located on the mitochondrial outer membrane and splices precursor tRNAs in Saccharomyces cerevisiae. Here, we demonstrate that the Sen complex cleaves the mitochondria-localized mRNA encoding Cbp1 (cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538567aa9e4bc319d39671522dac2c40
https://europepmc.org/articles/PMC4481206/
https://europepmc.org/articles/PMC4481206/
Autor:
Tatsuhisa Tsuboi1, Reina Yamazaki1, Risa Nobuta1, Ken Ikeuchi1, Shiho Makino1, Ayumi Ohtaki1, Yutaka Suzuki2, Tohru Yoshihisa3, Christopher Trotta4, Toshifumi Inada1 tinada@m.tohoku.ac.jp
Publikováno v:
Journal of Biological Chemistry. 6/26/2015, Vol. 290 Issue 26, p16021-16030. 10p.