Phase 2 Placebo-Controlled Trial of Two Vaccines to Prevent Ebola in Liberia

Autor: H. Clifford Lane, Risa Eckes, Fatorma Bolay, James Logue, Julian Wolfson, Jonathan Marchand, Dean Follmann, Tolbert Nyenswah, Francis Kateh, Martha Nason, François Roman, Ripley Ballou, Mark W. Feinberg, Swati B. Gupta, Birgit Grund, Eric Stavale, Krisztina Janosko, Mark D. Kieh, Melvin P. Johnson, Stephen B. Kennedy, James D. Neaton, Lisa E. Hensley, Thomas P. Monath, Greg G Grandits, Moses Badio, Elizabeth S. Higgs

Publikováno v: New England Journal of Medicine. 377:1438-1447

The safety and efficacy of vaccines to prevent Ebola virus disease (EVD) were unknown when the incidence of EVD was peaking in Liberia.We initiated a randomized, placebo-controlled, phase 3 trial of the chimpanzee adenovirus 3 vaccine (ChAd3-EBO-Z) a

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https://doi.org/10.1056/nejmoa1614067

Detection of a Substantial Rate of Multidrug‐Resistant Tuberculosis in an HIV‐Infected Population in South Africa by Active Monitoring of Sputum Samples

Autor: Monkwe Jethro Mathibedi, Ella Ntshani, Shaheen Hassim, Henry Masur, Pamela A. Shaw, Julia A. Metcalf, Risa Eckes, Nomso Stubbs, Lizette Malan, Phumelele Sangweni, Stephanus Komati

Publikováno v: Clinical Infectious Diseases. 50:1053-1059

Background Tuberculosis (TB) coinfection with human immunodeficiency virus (HIV) is a substantial problem in South Africa. There has been a presumption that drug-resistant strains of TB are common in South Africa, but few studies have documented this

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https://doi.org/10.1086/651119

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Autor: Badio, Moses, Lhomme, Edouard, Kieh, Mark, Beavogui, Abdoul Habib, Kennedy, Stephen B., Doumbia, Seydou, Leigh, Bailah, Sow, Samba O., Diallo, Alpha, Fusco, Daniela, Kirchoff, Matthew, Termote, Monique, Vatrinet, Renaud, Wentworth, Deborah, Esperou, Helène, Lane, H. Clifford, Pierson, Jerome, Watson-Jones, Deborah, Roy, Céline, D’Ortenzio, Eric, Greenwood, Brian, Chêne, Genevieve, Richert, Laura, Neaton, James D., Yazdanpanah, Yazdan, Abdoulaye, Coulibaly, Aboulhab, Jamilia, Akoo, Pauline, Akpa, Esther, Akpata, Robert, Albert, Sara, Ale, Boni Maxime, C. Andrews, Benetta, Anoma, Stephane, Assiandi, Saw-San, Augier, Augustin, Awuondo, Ken, Bagayoko, Aminata, Bakare, Nyasha, Balde, Abby, Bangura, Lamin Molecule, Barrington, Kesha, Barte de Saint Fare, Eric, Baseler, Beth, Bauder, Ali, Bauduin, Claire, Bawo, Luke, Habib Beavogui, Abdoul, Belson, Michael, Bererd, Marion, Beyslow, Teedoh, Binachon, Blandine, Blie, Julie, Bockstal, Viki, Boire, Youba, Boison, Patricia, Bolay, Fatorma, Boly, Aliou, Gael Borg, Anne, Bowers, Donna, Browne, Sarah, Cagniard, Barbara, Cahill, Kelly, Abdoulaye Camara, Aissata, Camara, Keira, Camara, Modet, Campion, Cécilia, Cash, Jennifer, Pin Chai, Siew, Chambelin, Francois, Chieck, Keita, Chêne, Geneviève, Ciancia, Séverine, Ndiaga Cisse, Papa, Clide, Elfrida, Colin, Céline, Coller, Beth-Ann, Siaka Conde, Djélikan, Cone, Katherine, Connor, Laurie, Connor, Nicholas, Boye Cooper, Joseph, Couffin-Cardiergues, Sandrine, Coulibaly, Fatoumata, Coulibaly, Mariam, Dabakuyo-Yonli, Sandrine, Dabitao, Djeneba, Damerval, Thierry, Davis, Bionca, Fadlu Deen, Gibrilla, Dekeyster, Eline, Delfraissy, Jean-François, Delmas, Christelle, Dembele, Rokia, Diakite, Mahamadou, Saliou Diallo, Mamadou, Diarra, Ayouba, Diawara, Oualy, Dighero-kemp, Bonnie, Diop, Samba, Diouf, Waly, Doepel, Laurie, Moise Doumbia, Moussa, Douoguih, Macaya, DuChêne, Alain, Duvenhage, Michael, Eckes, Risa Eckes, Egan, Avril, Enria, Luisa, Espérou, Hélène, Etienne, Cécile, Eyler, Allison, Faye, Sylvain, Fernandez, José, Fleck, Suzanne, Fofana, Vemy, Franklin, Kokulo, Gaddah, Auguste, Gaignet, Marylène, Gallagher, Katherine, Garcia Gozalbes, Julia, Grandits, Greg, Gray, Maima, Greijer, Astrid, Grue, Louis, Grund, Birgit, Guindo, Oumar, Gupta, Swati, Haidara, Fadima, Hamze, Benjamin, Hancox, Emma, Hart, Gavin, Hébert, Jean-Christophe, Heijnen, Esther, Hensley, Patricia, Hensley, Lisa, Higgs, Elisabeth, Hilton, Trudi, Holley, Preston, Hoover, Marie, Howard, Natasha, Hughes, Melissa, Ilo, Dicko, Imes, Jen, Irvine, Skip, Ishola, David, Jacob, Will, Jato, Yvonne, Johnson, Melvin, Jusu, Morrison, Sidiki Kaba, Aboubacar, Kante, Myriam, Katoudi, Judith, Keita, Sakoba, Kennedy, Stephen, Jide Keshinro, Babajide, Khon, Brian, Kiawu, Hassan, Kirchoff, Matt, Kodio, Mamoudou, Koivogui, Lamine, Kombi, Tania, Kopka, Stacy, Kowuors, Dickens, Lacabaratz, Christine, Lacarra, Boris, Lambert, Laurie, Lane, Cliff, Lee, Shona, Lees, Shelley, Lefevre, Annabelle, Lemarcis, Frederic, Lévy, Yves, Levy-Marchal, Claire, Lewally, Jemilla, Leyssen, Maarten, Liu, Ken, Lowe, Brett, Lysander, Julia, Madelaine, Claire, Mahamadou, Ibrah, Manno, Daniela, Marchand, Johnathan, Marynissen, Siegfried, Massaquoi, Moses B.F., Masson, Laure, Matard, Charly, Matthew, Onorato, McCullough, John, Mercier, Noemie, Michavila, Pauline, Miller, Tracey, Miranda, Alejandra, Mohamed, Soumaya, Mooney, Tom, Morsch, Hans, Muamba, Dally, Lukoo Ndamenyaa, Rita, Neaton, James, Neboua, Désiré, Nelson, Micki, Newell, Kevin, Nguyen, Vinh-kim, Nielsen, Leslie, Niouma, Millimouno, Offergeld, Kim, Onorato, Matthew, Onwuchekwa, Uma, Orsega, Susan, Ortega-Perez, Inmaculada, Osborne, Cynthia, Otieno, Tuda, Patel, Sushma, Peiffer-Smadj, Nathan, Phillips, Robert, Piot, Peter, Piziali, Micheal, Pong, Stephany, Proffitt, Calvin, Quach, Alexandre, Ramers-verhoeven, Corina, Randunu, Nadeeka, Rivière, Priscille, Robinson, Cynthia, Van Roey, Griet, Falk Russell, Amy, Samai, Sibiry Samake, Mohamed, Sangare, Ballan, Sanogo, Ibrahim, Sadio Sarro, Yeya, Sarro, Sadio, Saville, Mélanie, Sawadogo, Serge, Schvartz, Maxime, Schwimmer, Christine, Secka, Fatou, Seraphin, Jacques, Shelley, Denise, Siddiqui, Sophia, Simon, Jakub, Simpson, Shelly, Muyisa Sivahera, Billy, Skip, Irvine, Slater, Karen, Smolskis, Mary, Smout, Elizabeth, Snowden, Emily, Soutthiphong, Anne-Aygline, Sow, Samba, Sow, Ydrissa, Splinter, Daniel, Spreng, Simone, Stapleton, Helen, Stoop, Jeroen, Sweeney, Mary, Tamba, Sienneh, Tapia, Mili, Tegli, Jemee, Thiebaut, Rodolphe, Thompson, Greg, Tierney, John, Touré, Abdoulaye, Traina, Stacey, Traore, Awa, Traore, Moussa, Tyee, Tijili, Vallée, David, Van Der Donck, Katrien V, Verbruggen, Nadia, Vincent, Corine, Vogel, Susan, Wallet, Cedrick, Wesseh, Cecelia, Whitworth, Jimmy, Wiedemann, Aurelie, Willems, Wouter, Williams, Julian, Wilson, Barthalomew, Wissedi, Njoh, Wolf, Jayanthi, Woods, Ian, Wurie, Alie, Yamadjako, Delphine, Yaradouno, Marcel, Zeggani, Zara

Publikováno v: Trials
Trials, 2021, 22 (1), pp.86. ⟨10.1186/s13063-021-05035-9⟩

International audience; Abstract Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and saf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5180bac4f606a4467dc3e60706d28716