Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ripple, Man"'
Autor:
Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface. Im
Externí odkaz:
https://doaj.org/article/a5c3345e76dd43cfb753bcec8206e6d2
Autor:
Kit Curtius, Roshani V. Patel, Ripple Man, Jordan Fletcher, Victoria Cuthill, Susan K. Clark, Alexander C. von Roon, Andrew Latchford
Publikováno v:
Endoscopy.
Background Long-term pouch surveillance outcomes for familial adenomatous polyposis (FAP) are unknown. We aimed to quantify surveillance outcomes and to determine which of selected possible predictive factors are associated with pouch dysplasia. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c031853168ecbee58b43d5bdfe79f0
https://doi.org/10.1055/a-2038-0541
https://doi.org/10.1055/a-2038-0541
Autor:
Alistair Noble, Lydia Durant, Stella M. Dilke, Ripple Man, Isabel Martin, Roshani Patel, Lesley Hoyles, Edward T. Pring, Andrew Latchford, Susan K. Clark, Simon R. Carding, Stella C. Knight
INTRODUCTION: Familial adenomatous polyposis (FAP) is a condition caused by a constitutional pathogenic variant of the adenomatous polyposis coli gene that results in intestinal adenoma formation and colorectal cancer, necessitating pre-emptive colec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fe837c8e698a972ec13749a0f71cc7
https://ueaeprints.uea.ac.uk/id/eprint/89640/
https://ueaeprints.uea.ac.uk/id/eprint/89640/
Autor:
David Bernardo, Lydia Durant, Elizabeth R. Mann, Elizabeth Bassity, Enrique Montalvillo, Ripple Man, Rakesh Vora, Durga Reddi, Fahri Bayiroglu, Luis Fernández-Salazar, Nick R. English, Simon T.C. Peake, Jon Landy, Gui H. Lee, George Malietzis, Yi Harn Siaw, Aravinth U. Murugananthan, Phil Hendy, Eva Sánchez-Recio, Robin K.S. Phillips, Jose A. Garrote, Paul Scott, Julian Parkhill, Malte Paulsen, Ailsa L. Hart, Hafid O. Al-Hassi, Eduardo Arranz, Alan W. Walker, Simon R. Carding, Stella C. Knight
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 1, Pp 22-39.e5 (2016)
Background & Aims: Most knowledge about gastrointestinal (GI)-tract dendritic cells (DC) relies on murine studies where CD103+ DC specialize in generating immune tolerance with the functionality of CD11b+/â subsets being unclear. Information about h
Externí odkaz:
https://doaj.org/article/43a045023eba4751af960d5f5612c1ab
Autor:
Anne L. McCartney, Johanne Brooks, Naila Arebi, Matthew J. O’Connor, Régis Stentz, Jonathan Segal, Stella C. Knight, Stella Dilke, Dennis N. F. Lim, Alistair Noble, Lydia Durant, Simon R. Carding, Durga Reddi, Lesley Hoyles, Ailsa L. Hart, Ripple Man, P Hendy, Ravi Misra, Nadezhda Gicheva, E. Tobias Pring
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-16 (2020)
Microbiome
Microbiome
Background Bacteroides thetaiotaomicron (Bt) is a prominent member of the human intestinal microbiota that, like all gram-negative bacteria, naturally generates nanosized outer membrane vesicles (OMVs) which bud off from the cell surface. Importantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1fc17c89f0884af0668dfbb67b2cde
http://link.springer.com/article/10.1186/s40168-020-00868-z
http://link.springer.com/article/10.1186/s40168-020-00868-z
Autor:
Stella C. Knight, Lydia Durant, Susan K. Clark, Ripple Man, I Martin, Carding, Alistair Noble, Stella Dilke, Edward Pring, Andrew Latchford, Lesley Hoyles, Patel R
ObjectivesFamilial adenomatous polyposis (FAP) is a condition caused by a constitutional pathogenic variant of the adenomatous polyposis coli (APC) gene that results in intestinal adenoma formation and colorectal cancer (CRC), necessitating pre-empti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cba401c9167c8e95be78c1540550384
https://doi.org/10.1101/2021.05.05.21256687
https://doi.org/10.1101/2021.05.05.21256687
Autor:
Alistair, Noble, Lydia, Durant, Stella M, Dilke, Ripple, Man, Isabel, Martin, Roshani, Patel, Lesley, Hoyles, Edward T, Pring, Andrew, Latchford, Susan K, Clark, Simon R, Carding, Stella C, Knight
Publikováno v:
Clinical and translational gastroenterology. 13(7)
Familial adenomatous polyposis (FAP) is a condition caused by a constitutional pathogenic variant of the adenomatous polyposis coli gene that results in intestinal adenoma formation and colorectal cancer, necessitating pre-emptive colectomy. We sough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e78349de5d3c6843cb71b0ce05bbbf1a
https://pubmed.ncbi.nlm.nih.gov/35297393
https://pubmed.ncbi.nlm.nih.gov/35297393
Autor:
Steve James, Edward Pring, John T Jenkins, Ripple Man, Stella C. Knight, Simon R. Carding, Stella Dilke, Lydia Durant, Alistair Noble, Lesley Hoyles
We sought methods of rectifying microbiota:immune dysregulation as a route to prophylaxis and improved immunotherapy of colorectal cancer (CRC). CRC develops in gut epithelium, accompanied by low level inflammatory signaling, intestinal microbial dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467fbc97210d829ca4f395c25716a8c7
https://doi.org/10.1101/2021.02.15.21251750
https://doi.org/10.1101/2021.02.15.21251750
Autor:
Durant, Lydia, Stentz, Régis, Noble, Alistair, Brooks, Johanne, Gicheva, Nadezhda, Durga Reddi, O’Connor, Matthew J., Hoyles, Lesley, McCartney, Anne L., Ripple Man, E. Tobias Pring, Dilke, Stella, Hendy, Philip, Segal, Jonathan P., Lim, Dennis N. F., Misra, Ravi, Hart, Ailsa L., Arebi, Naila, Carding, Simon R., Knight, Stella C.
Additional file 1: Supplementary Figure 1. Bt OMVs induce diverse cytokines from whole colon tissue and marked IL-10 response from colonic LP mDC. Supplementary Figure 2. Plasmacytoid DC cytokine response to Bt and Bt OMVs in healthy controls. Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454059bb6b9764732b9399d0df5abb44
Deficient resident memory T-cell and CD8 T-cell response to commensals in inflammatory bowel disease
Autor:
Pooja Datt, Lesley Hoyles, Ripple Man, Ailsa Hart, Matthew J. O’Connor, Stella C. Knight, Toby Pring, Dennis N. F. Lim, Durga Reddi, P Hendy, Lydia Durant, Samuel P Costello, Sonia Bouri, Alistair Noble, Ayesha Akbar, Ana Wilson, Naila Arebi, Simon R. Carding, Anne L. McCartney, Jonathan Segal
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims The intestinal microbiota is closely associated with resident memory lymphocytes in mucosal tissue. We sought to understand how acquired cellular and humoral immunity to the microbiota differ in health versus inflammatory bowel di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370bd0e3a6da4fc89b3589f70d8f8129
http://hdl.handle.net/10044/1/74319
http://hdl.handle.net/10044/1/74319