Antibody signatures against viruses and microbiome reflect past and chronic exposures and associate with aging and inflammation

Autor: Sergio Andreu-Sánchez, Aida Ripoll-Cladellas, Anna Culinscaia, Ozlem Bulut, Arno R. Bourgonje, Mihai G. Netea, Peter Lansdorp, Geraldine Aubert, Marc Jan Bonder, Lude Franke, Thomas Vogl, Monique G.P. van der Wijst, Marta Melé, Debbie Van Baarle, Jingyuan Fu, Alexandra Zhernakova

Publikováno v: iScience, Vol 27, Iss 6, Pp 109981- (2024)

Summary: Encounters with pathogens and other molecules can imprint long-lasting effects on our immune system, influencing future physiological outcomes. Given the wide range of microbes to which humans are exposed, their collective impact on health i

Externí odkaz: https://doaj.org/article/a625eed26ff74ff68e49a04b0978d288

The landscape of expression and alternative splicing variation across human traits

Autor: García-Pérez, Raquel, Ramirez, Jose Miguel, Ripoll-Cladellas, Aida, Chazarra-Gil, Ruben, Oliveros, Winona, Soldatkina, Oleksandra, Bosio, Mattia, Rognon, Paul Joris, Capella-Gutierrez, Salvador, Calvo, Miquel, Reverter, Ferran, Guigó, Roderic, Aguet, François, Ferreira, Pedro G., Ardlie, Kristin G., Melé, Marta

Publikováno v: In Cell Genomics 11 January 2023 3(1)

The landscape of expression and alternative splicing variation across human traits

Autor: Raquel García-Pérez, Jose Miguel Ramirez, Aida Ripoll-Cladellas, Ruben Chazarra-Gil, Winona Oliveros, Oleksandra Soldatkina, Mattia Bosio, Paul Joris Rognon, Salvador Capella-Gutierrez, Miquel Calvo, Ferran Reverter, Roderic Guigó, François Aguet, Pedro G. Ferreira, Kristin G. Ardlie, Marta Melé

Publikováno v: Cell Genomics, Vol 3, Iss 1, Pp 100244- (2023)

Summary: Understanding the consequences of individual transcriptome variation is fundamental to deciphering human biology and disease. We implement a statistical framework to quantify the contributions of 21 individual traits as drivers of gene expre

Externí odkaz: https://doaj.org/article/d4d8673d5dce46658f913ea2f6071d9a

The genome sequence of the grape phylloxera provides insights into the evolution, adaptation, and invasion routes of an iconic pest

Autor: Claude Rispe, Fabrice Legeai, Paul D. Nabity, Rosa Fernández, Arinder K. Arora, Patrice Baa-Puyoulet, Celeste R. Banfill, Leticia Bao, Miquel Barberà, Maryem Bouallègue, Anthony Bretaudeau, Jennifer A. Brisson, Federica Calevro, Pierre Capy, Olivier Catrice, Thomas Chertemps, Carole Couture, Laurent Delière, Angela E. Douglas, Keith Dufault-Thompson, Paula Escuer, Honglin Feng, Astrid Forneck, Toni Gabaldón, Roderic Guigó, Frédérique Hilliou, Silvia Hinojosa-Alvarez, Yi-min Hsiao, Sylvie Hudaverdian, Emmanuelle Jacquin-Joly, Edward B. James, Spencer Johnston, Benjamin Joubard, Gaëlle Le Goff, Gaël Le Trionnaire, Pablo Librado, Shanlin Liu, Eric Lombaert, Hsiao-ling Lu, Martine Maïbèche, Mohamed Makni, Marina Marcet-Houben, David Martínez-Torres, Camille Meslin, Nicolas Montagné, Nancy A. Moran, Daciana Papura, Nicolas Parisot, Yvan Rahbé, Mélanie Ribeiro Lopes, Aida Ripoll-Cladellas, Stéphanie Robin, Céline Roques, Pascale Roux, Julio Rozas, Alejandro Sánchez-Gracia, Jose F. Sánchez-Herrero, Didac Santesmasses, Iris Scatoni, Rémy-Félix Serre, Ming Tang, Wenhua Tian, Paul A. Umina, Manuella van Munster, Carole Vincent-Monégat, Joshua Wemmer, Alex C. C. Wilson, Ying Zhang, Chaoyang Zhao, Jing Zhao, Serena Zhao, Xin Zhou, François Delmotte, Denis Tagu

Publikováno v: BMC Biology, Vol 18, Iss 1, Pp 1-25 (2020)

Abstract Background Although native to North America, the invasion of the aphid-like grape phylloxera Daktulosphaira vitifoliae across the globe altered the course of grape cultivation. For the past 150 years, viticulture relied on grafting-resistant

Externí odkaz: https://doaj.org/article/bc996b59e5fd405cb747afed645c9cef

Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods.

Autor: Neavin, Drew, Senabouth, Anne, Arora, Himanshi, Lee, Jimmy Tsz Hang, Ripoll-Cladellas, Aida, Franke, Lude, Prabhakar, Shyam, Ye, Chun Jimmie, McCarthy, Davis J., Melé, Marta, Hemberg, Martin, Powell, Joseph E.

Publikováno v: Genome Biology; 4/15/2024, Vol. 25 Issue 1, p1-24, 24p