Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rintaro Okoshi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53298 (2013)
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent p
Externí odkaz:
https://doaj.org/article/040ef11b836d45b9b239f7c9853a70f9
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29599 (2011)
Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated adeno
Externí odkaz:
https://doaj.org/article/79ca4d8e843e4a779749a359d09e2831
Publikováno v:
Atmospheric Environment. 89:392-402
Biomass burning emits large amounts of aerosol particles globally, influencing human health and climate, but the number and size of the particles is highly variable depending on fuel type, burning and meteorological conditions, and secondary reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3850d4330492ba42a6cfbc4bfe3d2413
https://doi.org/10.1016/j.atmosenv.2014.01.024
https://doi.org/10.1016/j.atmosenv.2014.01.024
Autor:
Kumiko Nakashima, Akira Nakagawara, Natsumi Kubo, Osamu Shimozato, Toshinori Ozaki, Rintaro Okoshi
Publikováno v:
Biochemical and Biophysical Research Communications. 403:405-411
It has been shown that MDM2 inhibits the transcriptional and pro-apoptotic activities of p73 but does not promote its proteasomal degradation. In this study, we found that MDM2 indirectly induces the degradation of p73 through the interaction with It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7251d94f7d0d9c99113fc197e882cf2
https://doi.org/10.1016/j.bbrc.2010.11.043
https://doi.org/10.1016/j.bbrc.2010.11.043
Publikováno v:
Biochemical and Biophysical Research Communications. 387:143-148
The expression of tumor suppressor p73 is regulated at mRNA and protein levels. It has been shown that E2F1 acts as a transcriptional activator for p73. In this study, we have found that deregulated expression of E2F1 increases the mRNA level of p73,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65e448a6ef69d609571cbc2d2490eb1
https://doi.org/10.1016/j.bbrc.2009.06.141
https://doi.org/10.1016/j.bbrc.2009.06.141
Publikováno v:
Biochemical and Biophysical Research Communications. 386:207-211
Tumor suppressor p73 plays an important role in the regulation of DNA damage response. E2F-1 acts as a transcriptional regulator for p73. In the present study, we have found that acetylation of E2F-1 has a critical role in the E2F-1-mediated transact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fbdd00d431231b78ed887fff2a9293
https://doi.org/10.1016/j.bbrc.2009.06.035
https://doi.org/10.1016/j.bbrc.2009.06.035
Autor:
Yuanyuan Li, Kiyohiro Ando, Akira Nakagawara, Nami Koida, Meixiang Sang, Cuizhi Geng, Osamu Shimozato, Baoen Shan, Toshinori Ozaki, Yuyan Zhu, Rintaro Okoshi
Publikováno v:
Genes to Cells. 14:775-788
Plk3, one of Polo-like kinase family members, is involved in the regulation of cell cycle progression and DNA damage response. In this study, we found that Plk3 inhibits pro-apoptotic activity of p73 through physical interaction and phosphorylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dd64a6dbed04976fed8f825c20c920
https://doi.org/10.1111/j.1365-2443.2009.01309.x
https://doi.org/10.1111/j.1365-2443.2009.01309.x
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53298 (2013)
PLoS ONE, Vol 8, Iss 1, p e53298 (2013)
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions to destabilize prior to the loss of adherent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b1e3f9e9bbe7903fd3a27998589795
https://pubmed.ncbi.nlm.nih.gov/23308187
https://pubmed.ncbi.nlm.nih.gov/23308187
Autor:
Osamu Shimozato, Natsumi Kubo, Toshinori Ozaki, Kumiko Nakashima, Rintaro Okoshi, Akira Nakagawara
Publikováno v:
Biochemical and biophysical research communications. 406(1)
Recently, we have described that CREB (cAMP-responsive element-binding protein) has the ability to transactivate tumor suppressor p53 gene in response to glucose deprivation. In this study, we have found that CREB forms a complex with p53 and repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40c69656ba690a7d523e3563135e682
https://pubmed.ncbi.nlm.nih.gov/21295542
https://pubmed.ncbi.nlm.nih.gov/21295542
Autor:
Natsumi Kubo, Yusuke Suenaga, Fangzhou Song, Toshinori Ozaki, Akira Nakagawara, Youquan Bu, Rintaro Okoshi, Meixiang Sang
Publikováno v:
Biochemical and biophysical research communications. 397(2)
NFBD1/MDC1 is a large nuclear protein involved in the early cellular response to DNA damage. Upon DNA damage, NFBD1 has an ability to facilitate the efficient DNA repair. In the present study, we have found that, in addition to DNA damage response, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05662549775a1bd5fe07dc1b19d6c470
https://pubmed.ncbi.nlm.nih.gov/20529673
https://pubmed.ncbi.nlm.nih.gov/20529673