Development of a novel class of selective human carbonic anhydrase IX inhibitors containing a trifluorohydroxy propanone pharmacophore

Autor: Nicolino Pala, Roberta Cadoni, Carrie Lomelino, Brian P. Mahon, Robert McKenna, Roberto Dallocchio, Alessandro Dessì, Mauro Carcelli, Viengsavanh Pimxayvong, Claudia Crosio, Rino Weber, Daniela Vullo, Claudiu Supuran, Mario Sechi

Publikováno v: 4st Satellite Meeting on Carbonic Anhydrase, Parma, 14-17/11/2019
info:cnr-pdr/source/autori:Nicolino Pala, Roberta Cadoni, Carrie Lomelino, Brian P. Mahon, Robert McKenna, Roberto Dallocchio, Alessandro Dessì, Mauro Carcelli, Viengsavanh Pimxayvong, Claudia Crosio, Rino Weber, Daniela Vullo, Claudiu Supuran, Mario Sechi/congresso_nome:4st Satellite Meeting on Carbonic Anhydrase/congresso_luogo:Parma/congresso_data:14-17%2F11%2F2019/anno:2019/pagina_da:/pagina_a:/intervallo_pagine

Carbonic anhydrases (CAs) are emerging as potential biological targets for cancer therapy. In particular, hCA IX isoform has been found to be expressed in a wide variety of malignancies and appear to be tightly regulated by micro-environmental hypoxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::43c3340500f9bd67a50f6ba6662982ed
http://www.cnr.it/prodotto/i/409899