Výsledky vyhledávání - "Rinnat M. Porat"

NF-κB functions as a tumour promoter in inflammation-associated cancer

Autor: Rinat Abramovitch, Eli Pikarsky, Simcha Urieli-Shoval, Eithan Galun, Sharon Amit, Yinon Ben-Neriah, Rinnat M. Porat, Elena Gutkovich-Pyest, Ilan Stein, Shafika Kasem

Publikováno v: Nature. 431:461-466

The causes of sporadic human cancer are seldom recognized, but it is estimated that carcinogen exposure and chronic inflammation are two important underlying conditions for tumour development, the latter accounting for approximately 20% of human canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d082b27ea124f93c9261372731e3dc9
https://doi.org/10.1038/nature02924

Zobrazit plný text záznamu

An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC

Autor: Daliah Galinsky, Chen Shochat, Moran Savion, Yael Goldberg, Dvorah Abeliovich, Revital Kariiv, Dani Bercovich, Tamar Hamburger, Tamar Peretz, Liat Ben-Avi, Rinnat M. Porat, Hana Strul, Eli Pikarsky, Israela Lerer, Ayala Hubert, Inbal Kedar

Publikováno v: Familial cancer. 9(2)

Mutations in DNA mismatch repair genes underlie lynch syndrome (HNPCC). Lynch syndrome resulting from mutations in MSH6 is considered to be attenuated in comparison to that caused by mutations in MLH1 and MSH2, thus more likely to be under diagnosed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767e14459d9dbe4d7ce27f19b982d929
https://pubmed.ncbi.nlm.nih.gov/19851887

Zobrazit plný text záznamu

Homozygosity of MSH2 c.1906G--C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I

Autor: Eli Pikarsky, Helen Toledano, Isaac Yaniv, Hagit N. Baris, Dani Bercovich, Inbal Kedar-Barnes, Israela Lerer, Tamar Peretz, Chen Shochat, Rinnat M. Porat, Dvorah Abeliovich, Yael Goldberg

Publikováno v: Familial cancer. 8(3)

Hereditary non-polyposis colorectal cancer is a cancer predisposition syndrome known to be caused by heterozygous germline mutations in DNA mismatch repair genes (MMR) most commonly hMLH1, hMSH2, hMSH6. Heterozygous mutations in one of these genes co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a865f0a8a29d86a2516471a4b75d13b5
https://pubmed.ncbi.nlm.nih.gov/19101824

Zobrazit plný text záznamu

Mutation spectrum in HNPCC in the Israeli population

Autor: Israela Lerer, Rinnat M. Porat, Tamar Peretz, Suzan Mendelson, Dvorah Abeliovich, Aviram Nissan, Tamar Hamburger, Yael Goldberg, Ayala Hubert, Chen Shochat, Eli Pikarski, Inbal Kedar, Dani Bercovich, Avital Eilat, Michal Sagi, Luna Kadouri

Publikováno v: Familial cancer. 7(4)

Hereditary non-polyposis colon cancer is caused by mutations in DNA mismatch repair genes. The mutation spectrum in the Israeli population is poorly documented except for the c.1906G>C Ashkenazi founder mutation in the hMSH2 gene. To report our exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f7b1d010cba74092d063b4726f78ae
https://pubmed.ncbi.nlm.nih.gov/18389388

Zobrazit plný text záznamu

Specific induction of tie1 promoter by disturbed flow in atherosclerosis-prone vascular niches and flow-obstructing pathologies

Autor: Gregory Barshtein, Leena Alhonen, Myriam Grunewald, Kari Alitalo, Ahuva Itin, Rinnat M. Porat, Eli Keshet, Anat Globerman

Publikováno v: Circulation research. 94(3)

Nonlaminar flow is a major predisposing factor to atherosclerosis. Yet little is known regarding hemodynamic gene regulation in disease-prone areas of the vascular tree in vivo. We have determined spatial patterns of expression of endothelial cell re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4217b9009d6897fd5ec00704c6b6c48d
https://pubmed.ncbi.nlm.nih.gov/14976137

Zobrazit plný text záznamu

Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis

Autor: Yuval Dor, Rinnat M. Porat, Eli Keshet

Publikováno v: American journal of physiology. Cell physiology. 280(6)

Development of microvascular networks is set to meet the metabolic requirements of the tissue they perfuse. Accordingly, impairment of oxygen homeostasis, either due to increased oxygen consumption or as a result of blood vessel occlusion, triggers c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dd10283fc2a83e88a76a3ecc065c12
https://pubmed.ncbi.nlm.nih.gov/11350731

Zobrazit plný text záznamu

Abstract 3163: ZMAT3, a signature gene for sporadic osteosarcoma

Autor: David Malkin, Jonathan D. Wasserman, Rinnat M. Porat, Noa Alon, Margaret Pienkowska, Cristina Baciu

Publikováno v: Cancer Research. 73:3163-3163

Osteosarcoma (OS) is a primary bone malignancy with high incidence in children and young adults. It frequently occurs in patients with strong cancer history (Li-Fraumeni syndrome, retinoblastoma), but the etiology of sporadic OS is still uncertain. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74a42f78abb0377d35e74defd5176f82
https://doi.org/10.1158/1538-7445.am2013-3163

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání