TCF4 trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophy.

Autor: Saha S; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, 52242, USA., Skeie JM; Department of Ophthalmology & Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA; Iowa Lions Eye Bank, Coralville, IA, 52241, USA., Schmidt GA; Iowa Lions Eye Bank, Coralville, IA, 52241, USA., Eggleston T; Iowa Lions Eye Bank, Coralville, IA, 52241, USA., Shevalye H; Iowa Lions Eye Bank, Coralville, IA, 52241, USA., Sales CS; Department of Ophthalmology & Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA; Iowa Lions Eye Bank, Coralville, IA, 52241, USA., Phruttiwanichakun P; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, 52242, USA., Dusane A; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, 52242, USA., Field MG; Department of Ophthalmology & Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Rinkoski TA; Department of Ophthalmology, 200 1st St SW, Mayo Clinic, Rochester, MN, 55905, USA., Fautsch MP; Department of Ophthalmology, 200 1st St SW, Mayo Clinic, Rochester, MN, 55905, USA., Baratz KH; Department of Ophthalmology, 200 1st St SW, Mayo Clinic, Rochester, MN, 55905, USA., Roy M; Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, 21287, USA., Jun AS; Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, 21287, USA., Pendleton C; The University of Iowa College of Dentistry and Dental Clinics, Iowa City, IA, USA., Salem AK; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, 52242, USA. Electronic address: aliasger-salem@uiowa.edu., Greiner MA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, IA, 52242, USA; Department of Ophthalmology & Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA; Iowa Lions Eye Bank, Coralville, IA, 52241, USA. Electronic address: mark-greiner@uiowa.edu.

Publikováno v: Redox biology [Redox Biol] 2024 Nov; Vol. 77, pp. 103348. Date of Electronic Publication: 2024 Sep 10.

Transgene expression of Stanniocalcin-1 provides sustained intraocular pressure reduction by increasing outflow facility.

Autor: Roddy GW; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America., Roy Chowdhury U; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America., Anderson KJ; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America., Rinkoski TA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America., Hann CR; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America., Chiodo VA; Department of Ophthalmology, University of Florida, Gainesville, Florida, United States of America., Smith WC; Department of Ophthalmology, University of Florida, Gainesville, Florida, United States of America., Fautsch MP; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America.

Publikováno v: PloS one [PLoS One] 2022 May 31; Vol. 17 (5), pp. e0269261. Date of Electronic Publication: 2022 May 31 (Print Publication: 2022).

Characterization of a dual media system for culturing primary normal and Fuchs endothelial corneal dystrophy (FECD) endothelial cells.

Autor: Rinkoski TA; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Bahler CK; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Pacheco JM; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Khanna ML; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Holmes DM; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Roy Chowdhury U; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Baratz KH; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Patel SV; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Maguire LJ; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Wieben ED; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Fautsch MP; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America.

Publikováno v: PloS one [PLoS One] 2021 Sep 29; Vol. 16 (9), pp. e0258006. Date of Electronic Publication: 2021 Sep 29 (Print Publication: 2021).

Disease Expression and Familial Transmission of Fuchs Endothelial Corneal Dystrophy With and Without CTG18.1 Expansion.

Autor: Xu TT; Alix School of Medicine, Mayo Clinic, Rochester, Minnesota, United States., Li YJ; Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, United States.; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Afshari NA; Shiley Eye Institute, University of California, San Diego, La Jolla, California, United States., Aleff RA; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States., Rinkoski TA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Patel SV; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Maguire LJ; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Edwards AO; Oregon Retina Division, Sterling Vision, Eugene, Oregon, United States.; Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon, United States., Brown WL; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Fautsch MP; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Wieben ED; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States., Baratz KH; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.

Publikováno v: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2021 Jan 04; Vol. 62 (1), pp. 17.

Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits.

Autor: Roy Chowdhury U; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Kudgus RA; Department of Oncology Research, Mayo Clinic, Rochester, MN, United States of America., Rinkoski TA; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Holman BH; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Bahler CK; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Hann CR; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America., Reid JM; Department of Oncology Research, Mayo Clinic, Rochester, MN, United States of America., Dosa PI; Department of Medicinal Chemistry, Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, MN, United States of America., Fautsch MP; Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America.

Publikováno v: PloS one [PLoS One] 2020 Apr 16; Vol. 15 (4), pp. e0231841. Date of Electronic Publication: 2020 Apr 16 (Print Publication: 2020).