Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a multisite, open-label randomised controlled trial.

Autor: Brown JA; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland., Ringera IK; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; SolidarMed, Partnerships for Health, Maseru, Lesotho., Luoga E; Ifakara Health Institute, Ifakara, Tanzania; St Francis Referral Hospital, Ifakara, Tanzania., Bresser M; University of Basel, Basel, Switzerland; Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Mothobi B; SolidarMed, Partnerships for Health, Maseru, Lesotho., Kabundi L; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Ilunga M; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Mokhele K; SolidarMed, Partnerships for Health, Maseru, Lesotho., Isaac AB; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Tsoaeli N; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Mbaya T; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Simba B; Management and Development for Health, Dar es Salaam, Tanzania., Mayogu K; Management and Development for Health, Dar es Salaam, Tanzania., Mabula E; Management and Development for Health, Dar es Salaam, Tanzania., Cheleboi M; Seboche Mission Hospital, Seboche, Lesotho., Molatelle M; Seboche Mission Hospital, Seboche, Lesotho., Kimera N; Ifakara Health Institute, Ifakara, Tanzania., Mollel GJ; Ifakara Health Institute, Ifakara, Tanzania; St Francis Referral Hospital, Ifakara, Tanzania., Sando D; Management and Development for Health, Dar es Salaam, Tanzania., Tschumi N; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland., Amstutz A; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital and University of Oslo, Oslo, Norway; Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK., Thahane L; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho; Baylor College of Medicine, Houston, TX, USA., Hlasoa MM; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Kayembe BP; Baylor College of Medicine Children's Foundation Lesotho, Maseru, Lesotho., Muhairwe J; SolidarMed, Partnerships for Health, Maseru, Lesotho., Klimkait T; Molecular Virology, Department of Biomedicine, Basel, Switzerland., Glass TR; University of Basel, Basel, Switzerland; Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Weisser M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland; Ifakara Health Institute, Ifakara, Tanzania; Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Labhardt ND; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address: niklaus.labhardt@usb.ch.

Publikováno v: The Lancet. Global health [Lancet Glob Health] 2024 Aug; Vol. 12 (8), pp. e1312-e1322.