Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rinette Woo"'
Autor:
Chandani Limbad, Nathan Salomonis, Isabel Adrados, Sean D. McAllister, Liliana Soroceanu, Ryuichi Murase, Klemens Weitenthaler, Rinette Woo, Pierre-Yves Desprez
Publikováno v:
Cannabis Cannabinoid Res
Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding 1 (ID1) in cancer cells, leading to inhibition of tumor progression
Autor:
Max Sidorov, Altaf A. Dar, Tam Le Ho, Ryan J Ice, Ari Nazarian, Stephen Chang, David de Semir, Angela Kim, HanKyul Kim, Stanley P. L. Leong, Mohammed Kashani-Sabet, Alyssia Oh, Gregory J. Tranah, Aida Rodriguez-Brotons, Tri Luu, Kevin B. Kim, Liliana Soroceanu, Des Stone, Sean D. McAllister, Michelle B. Chen, Mehdi Nosrati, Damon Jian, Rinette Woo, Pierre-Yves Desprez
Publikováno v:
British Journal of Cancer
Background Patient-derived xenograft (PDX) mouse tumour models can predict response to therapy in patients. Predictions made from PDX cultures (PDXC) would allow for more rapid and comprehensive evaluation of potential treatment options for patients,
Autor:
Dana Messinger, Micah Harris, Jessica Cummings, Chase Thomas, Tao Yang, Stefan Sweha, Rinette Woo, Robert Siddaway, Martin Burkert, Stefanie Stallard, Tingting Qin, Brendan Mullan, Ruby Siada, Ramya Ravindran, Michael Niculcea, Abigail Dowling, Joshua Bradin, Kevin Ginn, Melissa Gener, Kathleen Dorris, Nicholas Vitanza, Susanne Schmidt, Jasper Spitzer, Jiang Li, Mariella Filbin, Xuhong Cao, Maria Castro, Pedro Lowenstein, Rajen Mody, Arul Chinnaiyan, Pierre-Yves Desprez, Sean McAllister, Matthew Dun, Cynthia Hawkins, Sebastian Waszak, Sriram Venneti, Carl Koschmann, Viveka Yadav
Publikováno v:
Neuro-Oncology. 24:vii40-vii40
Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis. The mechanism behind tumor invasion is currently not well understood. Previous reports demonstrate upregulation of the protein ID1 with
Autor:
Dana Messinger, Micah K Harris, Jessica R Cummings, Chase Thomas, Tao Yang, Stefan R Sweha, Rinette Woo, Robert Siddaway, Martin Burkert, Stefanie Stallard, Tingting Qin, Brendan Mullan, Ruby Siada, Ramya Ravindran, Michael Niculcea, Abigail R Dowling, Joshua Bradin, Kevin F Ginn, Melissa A H Gener, Kathleen Dorris, Nicholas A Vitanza, Susanne V Schmidt, Jasper Spitzer, Jiang Li, Mariella G Filbin, Xuhong Cao, Maria G Castro, Pedro R Lowenstein, Rajen Mody, Arul Chinnaiyan, Pierre-Yves Desprez, Sean McAllister, Matthew D Dun, Cynthia Hawkins, Sebastian M Waszak, Sriram Venneti, Carl Koschmann, Viveka Nand Yadav
Publikováno v:
Neuro-oncology.
Background Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor invasion. Previous reports demonstrate upregulation of the protein ID
Autor:
Kevin Ginn, Pierre-Yves Desprez, Micah Harris, Cynthia Hawkins, Michael Niculcea, Chase Thomas, Maria G. Castro, Sriram Venneti, Tao Yang, Melissa Gener, Cummings, Xuhong Cao, Sandra S. McAllister, Stefanie Stallard, Messinger D, Jasper Spitzer, Carl Koschmann, Mariella G. Filbin, Chinnaiyan A, Tingting Qin, Pedro R. Lowenstein, Sebastian M. Waszak, Kathleen Dorris, Jiang Li, Viveka Yadav, Burkert M, Ramya Ravindran, Robert Siddaway, Rinette Woo, Susanne V. Schmidt, Ruby Siada, Rajen Mody, Brendan Mullan, Nicholas A Vitanza
Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive brain tumor with rare survival beyond two years. This poor prognosis is largely due to the tumor’s highly infiltrative and invasive nature. Previous reports demonstrate upregulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a6667772b4c5047c8ed9961739ba7e
https://doi.org/10.1101/2021.05.10.443452
https://doi.org/10.1101/2021.05.10.443452
Autor:
Larry Dickinson, Pratiksha Dighe, Sean D. McAllister, Pierre Yves Desprez, Mehdi Nosrati, Liliana Soroceanu, Nathan Salomonis, Rinette Woo, Anu Bhattacharjee
Publikováno v:
Neuro-Oncology. 23:vi177-vi177
Recurrent glioblastomas (GBM) are notoriously difficult to treat, and in spite of aggressive chemo- and radiation therapy they inevitably recur in almost all GBM patients within 14 months following initial diagnosis. To interrogate pathways driving t
Autor:
Carl Koschmann, Micah Harris, Sriram Venneti, Sean D. McAllister, Kevin Ginn, Kathleen Dorris, Viveka Nand Yadav, Jasper Spitzer, Mariella G Filbin, Rajen Mody, Stefanie Stallard, Brendan Mullan, Dana Messinger, Pedro R. Lowenstein, Cynthia Hawkins, Jessica R. Cummings, Jiang Li, Nicholas A Vitanza, Ruby Siada, Tao Yang, Sebastian M Waszak, Melissa Gener, Tingting Qin, Robert Siddaway, Ramya Ravindran, Chase Thomas, Xuhong Cao, Maria G. Castro, Martin Burkert, Susanne Schmidt, Pierre Yves Desprez, Arul M. Chinnaiyan, Michael Niculcea, Rinette Woo
Publikováno v:
Neuro Oncol
Diffuse intrinsic pontine glioma (DIPG) is a highly aggressive pediatric brain tumor with rare survival beyond two years. This poor prognosis is largely due to the tumor's highly infiltrative and invasive nature. Nearly 80% of DMGs harbor K27M mutati
Autor:
Micah Harris, Cynthia Hawkins, Sriram Venneti, Ruby Siada, Tingting Qin, Sean D. McAllister, Arul M. Chinnaiyan, Carl Koschmann, Xuhong Cao, Pierre Yves Desprez, Ramya Ravindran, Maria G. Castro, Rajen Mody, Robert Siddaway, Rinette Woo, Pedro R. Lowenstein, Brendan Mullan, Stefanie Stallard, Viveka Nand Yadav, Zachary Miklja, Amy L. Pasternak
Publikováno v:
Neuro-Oncology
BACKGROUND Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no curative therapies. Inhibitor of DNA binding (ID) proteins are key regulators of gene differentiation during embryogenesis. Previous work has shown that H3
Autor:
Brendan Mullan, Jessica R. Cummings, Pierre Yves Desprez, Micah Harris, Viveka Nand Yadav, Sriram Venneti, Sean D. McAllister, Maria G. Castro, Arul M. Chinnaiyan, Ramya Ravindran, Cynthia Hawkins, Michael Niculcea, Chase Thomas, Carl Koschmann, Rajen Mody, Tingting Qin, Robert Siddaway, Pedro R. Lowenstein, Stefanie Stallard, Xuhong Cao, Rinette Woo, Ruby Siada
Publikováno v:
Neuro-Oncology
Diffuse intrinsic pontine gliomas (DIPGs) are lethal pediatric brain tumors with no effective therapies beyond radiation. The highly invasive nature of DIPG is key to its aggressive phenotype, but the factors and mechanisms contributing to this aggre
Autor:
Alex Dickson, Hideki Aihara, Mohammed Kashani-Sabet, Junwei Shi, Jorden A. Johnson, Steven E. Kirberger, Ke Shi, Michael F. Ciccone, Peter D. Ycas, Andrew K. Urick, William C. K. Pomerantz, Rinette Woo, Camila O. dos Santos, Sean D. McAllister, Huda Zahid, Chen Chen
Publikováno v:
Organicbiomolecular chemistry. 17(7)
Bromodomain and PHD finger containing protein transcription factor (BPTF) is an epigenetic protein involved in chromatin remodelling and is a potential anticancer target. The BPTF bromodomain has one reported small molecule inhibitor (AU1, rac-1). He