Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rinesh Godfrey"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/63ccfb23759f4d28892d27f04f4e9456
Autor:
Marc Dorenkamp, Madina Nasiry, Dilvin Semo, Sybille Koch, Ivonne Löffler, Gunter Wolf, Holger Reinecke, Rinesh Godfrey
Publikováno v:
Cells, Vol 12, Iss 3, p 513 (2023)
Monocytes play a vital role in the development of cardiovascular diseases. Type 2 diabetes mellitus (T2DM) is a major CVD risk factor, and T2DM-induced aberrant activation and enhanced migration of monocytes is a vital pathomechanism that leads to at
Externí odkaz:
https://doaj.org/article/27fb78a69b7e44b7acd3f47666002886
Autor:
Yahya Sohrabi, Glenn V. H. Sonntag, Laura C. Braun, Sina M. M. Lagache, Marie Liebmann, Luisa Klotz, Rinesh Godfrey, Florian Kahles, Johannes Waltenberger, Hannes M. Findeisen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
ObjectivesThe concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synth
Externí odkaz:
https://doaj.org/article/c7afa72b2cbb4133999e625a802a0e29
Autor:
Yahya Sohrabi, Jéssica Cristina Dos Santos, Marc Dorenkamp, Hannes Findeisen, Rinesh Godfrey, Mihai G Netea, Leo AB Joosten
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract COVID‐19 is a severe health problem in many countries and has altered day‐to‐day life in the whole world. This infection is caused by the SARS‐CoV‐2 virus, and depending on age, sex and health status of the patient, it can present
Externí odkaz:
https://doaj.org/article/1b1d4dd4ec544a5daa745721951e55be
Autor:
Yahya Sohrabi, Sina M. M. Lagache, Lucia Schnack, Rinesh Godfrey, Florian Kahles, Dennis Bruemmer, Johannes Waltenberger, Hannes M. Findeisen
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Introduction: Cells of the innate immune system particularly monocytes and macrophages have been recognized as pivotal players both during the initial insult as well as the chronic phase of atherosclerosis. It has recently been shown that oxidized lo
Externí odkaz:
https://doaj.org/article/d623633f3fab43129269e46d827bfe29
Autor:
Pia Hemling, Henny Schulten, Darya Zibrova, Johannes Waltenberger, Regine Heller, Hannes M. Findeisen, Gernot Desoye, Jasmin Strutz, Yahya Sohrabi, Rinesh Godfrey
Publikováno v:
International Journal of Cardiology, 308, 73-81. Elsevier Ireland Ltd
BACKGROUND: Diabetes mellitus is an important cardiovascular risk factor characterized by elevated plasma glucose levels. High glucose (HG) negatively influences endothelial cell (EC) function, which is characterized by the inability of ECs to respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a652dcb7896a3c8f4d8cd7d87b806d57
https://doi.org/10.1016/j.ijcard.2019.12.065
https://doi.org/10.1016/j.ijcard.2019.12.065
Autor:
Dilvin Semo, Julius Obergassel, Marc Dorenkamp, Pia Hemling, Jasmin Strutz, Ursula Hiden, Nicolle Müller, Ulrich Alfons Müller, Sajan Ahmad Zulfikar, Rinesh Godfrey, Johannes Waltenberger
Publikováno v:
Journal of Clinical Medicine
Volume 12
Issue 4
Pages: 1356
Journal of Clinical Medicine, 12(4):1356. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 12
Issue 4
Pages: 1356
Journal of Clinical Medicine, 12(4):1356. Multidisciplinary Digital Publishing Institute (MDPI)
Purpose: Hyperglycaemia-induced oxidative stress and inflammation contribute to vascular cell dysfunction and subsequent cardiovascular events in T2DM. Selective sodium-glucose co-transporter-2 (SGLT-2) inhibitor empagliflozin significantly improves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81817f84773b8300eafa1a7b7f81b7c
https://doi.org/10.3390/jcm12041356
https://doi.org/10.3390/jcm12041356
Publikováno v:
European Heart Journal. 42
Purpose Aberrant activation of Type 2 Diabetes mellitus (T2DM) monocytes is an important pathomechanism leading to restricted arteriogenesis and augmented atherosclerosis, hereby, accelerating CAD and PAD. Tyrosine phosphatase SHP-2 was found to be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b6ead7a4f6dc3907ed215fe7c3cf1a
https://doi.org/10.1093/eurheartj/ehab724.3350
https://doi.org/10.1093/eurheartj/ehab724.3350
Autor:
Rinesh Godfrey, Johannes Waltenberger, BA Imhof, SK Shanmuganathan, FD Böhmer, S Adama, UA Müller, N Müller, D Semo
Publikováno v:
Late Breaking Abstracts Diabetes Kongress 2021 – 55. Jahrestagung der DDG Präzisionsmedizin – Eine Reise in die Zukunft der Diabetologie www.diabeteskongress.de.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::514cdc7ece8a1d39d71ddf79c177775b
https://doi.org/10.1055/s-0041-1730854
https://doi.org/10.1055/s-0041-1730854
Publikováno v:
Trends in Endocrinology & Metabolism
Trends in Endocrinology and Metabolism
Trends in Endocrinology and Metabolism
Benign hepatosteatosis, affected by lipid uptake, de novo lipogenesis and fatty acid (FA) oxidation, progresses to non-alcoholic steatohepatitis (NASH) on stress and inflammation. A key macronutrient proposed to increase hepatosteatosis and NASH risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c1cb0c130610edb2b8a63127820812