Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Rina Venerando"'
Autor:
Giulia Elda Valenti, Antonella Roveri, Rina Venerando, Paola Menichini, Paola Monti, Bruno Tasso, Nicola Traverso, Cinzia Domenicotti, Barbara Marengo
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 3 (2023)
Neuroblastoma (NB) is a paediatric cancer with noteworthy heterogeneity ranging from spontaneous regression to high-risk forms that are characterised by cancer relapse and the acquisition of drug resistance. The most-used anticancer drugs exert their
Externí odkaz:
https://doaj.org/article/651feca5f0c3466cbdb9ac151cb59b07
Publikováno v:
Polymers, Vol 15, Iss 7, p 1616 (2023)
The progression of smoking-related diseases is characterized by macrophage-mediated inflammation, which is responsible for an increased expression of proinflammatory cytokines and galectins, molecules that bind specifically to β-galactoside sugars.
Externí odkaz:
https://doaj.org/article/aeb108c8be2349779c9482019ecb7d61
Autor:
Maria Luisa Di Paolo, Manuela Cervelli, Paolo Mariottini, Alessia Leonetti, Fabio Polticelli, Michela Rosini, Andrea Milelli, Filippo Basagni, Rina Venerando, Enzo Agostinelli, Anna Minarini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 740-752 (2019)
Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1–9) or methoctramine (10–14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) a
Externí odkaz:
https://doaj.org/article/1dbc6fd3202f4f33b7717030344a779d
Autor:
Alice Donato, Elisa Belluzzi, Elena Mattiuzzo, Rina Venerando, Massimiliano Cadamuro, Pietro Ruggieri, Vincenzo Vindigni, Paola Brun
Publikováno v:
Polymers, Vol 14, Iss 9, p 1817 (2022)
Inflammation and the accumulation of reactive oxygen species (ROS) play an important role in the structural and functional modifications leading to skin ageing. The reduction of inflammation, cellular oxidation and dermal extracellular matrix (ECM) a
Externí odkaz:
https://doaj.org/article/60f3f9df941945599b1a6648330d917c
Autor:
Giovanni Miotto, Monica Rossetto, Maria Luisa Di Paolo, Laura Orian, Rina Venerando, Antonella Roveri, Ana-Marija Vučković, Valentina Bosello Travain, Mattia Zaccarin, Lucio Zennaro, Matilde Maiorino, Stefano Toppo, Fulvio Ursini, Giorgio Cozza
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Ferroptosis is a form of cell death primed by iron and lipid hydroperoxides and prevented by GPx4. Ferrostatin-1 (fer-1) inhibits ferroptosis much more efficiently than phenolic antioxidants. Previous studies on the antioxidant efficiency of fer-1 ad
Externí odkaz:
https://doaj.org/article/c7bedb24953f45d1a9f13240e20486a0
Autor:
Elena Mattiuzzo, Alessia Faggian, Rina Venerando, Andrea Benetti, Elisa Belluzzi, Giovanni Abatangelo, Pietro Ruggieri, Paola Brun
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 286 (2021)
β-caryophyllene (BCP), a plant-derived sesquiterpene, has been reported to have anti-inflammatory and antioxidant effects. The purpose of this study is to evaluate the effects of BCP in combination with ascorbic acid (AA) and d-glucosamine (GlcN) ag
Externí odkaz:
https://doaj.org/article/999c4ce461cd4590aec76fe7550c1cf0
Autor:
Elena Tarricone, Elena Mattiuzzo, Elisa Belluzzi, Rossella Elia, Andrea Benetti, Rina Venerando, Vincenzo Vindigni, Pietro Ruggieri, Paola Brun
Publikováno v:
Cells, Vol 9, Iss 6, p 1328 (2020)
The development and progression of osteoarthritis (OA) is associated with macrophage-mediated inflammation that generates a broad spectrum of cytokines and reactive oxygen species (ROS). This study investigates the effects of mid-MW hyaluronic acid (
Externí odkaz:
https://doaj.org/article/6f6ac1c62fb94ef3b5d41acfd252e573
Autor:
Matilde Maiorino, Elena Tibaldi, Giorgio Cozza, Antonella Roveri, Luciana Bordin, Valentina Bosello Travain, Ana-Marija Vučković, Fulvio Ursini, Giovanni Miotto, Rina Venerando, Stefano Toppo
Publikováno v:
Free Radical Biology and Medicine. 167:45-53
Ferroptosis is a non-accidental, regulated form of cell death operated by lipid peroxidation under strict control of GPx4 activity. This is consistent with the notion that lipid peroxidation is initiated by radicals produced from decomposition of tra
Autor:
Antonella Roveri, Giorgio Cozza, Ana-Marija Vučković, Matilde Maiorino, Valentina Bosello Travain, Mattia Zaccarin, Fulvio Ursini, Stefano Toppo, Rina Venerando, Giovanni Miotto
GPx8 is a glutathione peroxidase homolog inserted in the membranes of endoplasmic reticulum (ER), where it seemingly plays a role in controlling redox status by preventing the spill of H2O2. We addressed the impact of GPx8 silencing on the lipidome o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5c52d605fc7e59bf663d33ce83a11d
https://www.bib.irb.hr/1147205
https://www.bib.irb.hr/1147205
Autor:
Antonella Roveri, Monica Rossetto, Luciana Bordin, Mattia Zaccarin, Ana-Marija Vučković, Giovanni Miotto, Rina Venerando, Matilde Maiorino, Fulvio Ursini, Stefano Toppo, Giorgio Cozza, Valentina Bosello Travain
Publikováno v:
FEBS lettersReferences. 594(4)
Ras-selective lethal small molecule 3 (RSL3), a drug candidate prototype for cancer chemotherapy, triggers ferroptosis by inactivating the glutathione peroxidase glutathione peroxidase 4 (GPx4). Here, we report the purification of the protein indispe