Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rina, Leyva"'
Autor:
David Kellstein, Rina Leyva
Publikováno v:
Drugs in R&D, Vol 20, Iss 3, Pp 237-247 (2020)
Abstract Introduction Ibuprofen and acetaminophen provide analgesia via different mechanisms of action and do not exhibit drug–drug interactions; therefore, combining low doses of each may provide greater efficacy without compromising safety. Objec
Externí odkaz:
https://doaj.org/article/86417409a2aa4885a9204b484f5bab10
Autor:
Sanela Tarabar, Debra Kelsh, Bradley Vince, Rina Leyva, Dongweon Song, Kyle Matschke, David E. Kellstein, Suzanne Meeves, Mario Cruz-Rivera
Publikováno v:
Drugs in R&D, Vol 20, Iss 1, Pp 23-37 (2020)
Abstract Introduction A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. Methods We repor
Externí odkaz:
https://doaj.org/article/ffd5f1abe8a9407585b18ff53cbc6a95
Publikováno v:
Clinical Therapeutics. 43:1213-1227
PURPOSE This study evaluated antipyretic efficacy and onset of a novel fixed-dose combination (FDC) of ibuprofen (IBU; 250 mg) and acetaminophen (APAP; 500 mg) compared with placebo and IBU or APAP monocomponents. MET: This single-center, randomized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581f9f294853d9b4712ce19d91f1c5a8
https://doi.org/10.1016/j.clinthera.2021.05.004
https://doi.org/10.1016/j.clinthera.2021.05.004
Autor:
Rina Leyva, David Kellstein
Publikováno v:
Drugs in R&D
Drugs in R&D, Vol 20, Iss 3, Pp 237-247 (2020)
Drugs in R&D, Vol 20, Iss 3, Pp 237-247 (2020)
Introduction Ibuprofen and acetaminophen provide analgesia via different mechanisms of action and do not exhibit drug–drug interactions; therefore, combining low doses of each may provide greater efficacy without compromising safety. Objectives The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc0d61e8c11221fb2a8d958c0c25230
http://europepmc.org/articles/PMC7419400
http://europepmc.org/articles/PMC7419400
Autor:
David Kellstein, Mario Cruz-Rivera, Ed Paluch, Derek Muse, Shawn Searle, Elizabeth DePadova, Rina Leyva
Publikováno v:
The Clinical Journal of Pain. 36:495-504
A previous pilot study demonstrated that various fixed-dose combinations (FDCs) of ibuprofen (IBU) and acetaminophen (APAP) provided analgesic efficacy comparable to a higher dose of IBU, with the same safety profile. These studies further evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db03e24d84ed29c01b8155f7070b3cc
https://doi.org/10.1097/ajp.0000000000000828
https://doi.org/10.1097/ajp.0000000000000828
Autor:
Kyle Matschke, Sanela Tarabar, Mario Cruz-Rivera, David Kellstein, Debra Kelsh, Bradley Vince, Suzanne Meeves, Dongweon Song, Rina Leyva
Publikováno v:
Drugs in R&D
Drugs in R&D, Vol 20, Iss 1, Pp 23-37 (2020)
Drugs in R&D, Vol 20, Iss 1, Pp 23-37 (2020)
Introduction A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. Methods We report three c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4bfe71fd10fcdd436fba4782b68d3d
https://pubmed.ncbi.nlm.nih.gov/32130679
https://pubmed.ncbi.nlm.nih.gov/32130679
Publikováno v:
International journal of clinical pharmacology and therapeutics. 55(7)
Objective Evaluate adherence of US consumers to proposed label directions for a new 400 mg ibuprofen formulation. Methods In this single-arm, open-label, multicenter, 30-day study simulating an over-the-counter (OTC)-like environment, US analgesic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6072b7b83753e2fe3093c0c85d386d6e
https://pubmed.ncbi.nlm.nih.gov/28513425
https://pubmed.ncbi.nlm.nih.gov/28513425
Publikováno v:
Drugs in R&D
Background A novel ibuprofen (IBU) formulation, Advil® Film-Coated Tablets (IBUNa), was developed. Objective Pharmacokinetic comparison of IBUNa versus other IBU formulations. Study Design Two randomized, single-dose, open-label, five-way crossover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82451ba7b17cb24dfe1d91f8061774c4
http://europepmc.org/articles/PMC4269818
http://europepmc.org/articles/PMC4269818
Autor:
Patricia Corby, Steven C. Levine, Jillian Wallen, Paul Creighton, Tanya Mathew, Gary E. Jeffers, Paul S. Casamassimo, Othman Shibly, Rina Leyva, Arthur S. Kuperstein, Eric T. Stoopler, Sharon M. Gordon, Paul A. Moore, Sean G. Boynes, Stanley N. Turetzky, Cynthia L Idzik-starr, Sebastian G. Ciancio, Elliot V. Hersh, Athena Papas
Publikováno v:
The Journal of the American Dental Association. 144:517-526
Background The authors evaluated the efficacy and tolerability of 10 percent and 20 percent benzocaine gels compared with those of a vehicle (placebo) gel for the temporary relief of toothache pain. They also assessed the compliance with the label do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a2c166a0f197b835508729430ca514
https://doi.org/10.14219/jada.archive.2013.0154
https://doi.org/10.14219/jada.archive.2013.0154
Autor:
I J Mahoney, Anne Kane, Julie McKinney, Rina Leyva, Cheleste M. Thorpe, Debra D. Poutsiaka, Lisa Davidson, L. A. McDermott, Barry R. Goldin, David R. Snydman, L Lathrop Stern, C Baez-Giangreco
Publikováno v:
Journal of applied microbiology. 122(5)
Aim To develop a novel validated method for the isolation of Bifidobacterium animalis ssp. lactis BB-12 (BB-12) from faecal specimens and apply it to studies of BB-12 and Lactobacillus rhamnosus GG (LGG) recovered from the healthy human gastrointesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac7430e3df708284a77d6d1c872207d
https://pubmed.ncbi.nlm.nih.gov/28256070
https://pubmed.ncbi.nlm.nih.gov/28256070