Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rin Mizuno"'
Autor:
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Chenfeng He, Yuki Nakamura, Kosuke Kawaguchi, Masakazu Toi, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Spatial transcriptomics reveal how distant cancer affect gene expression and zonation in mouse liver in a manner that differs between biological pathways.
Externí odkaz:
https://doaj.org/article/48608d65ba534a52a3c3a5a77a96a0fd
Autor:
Rin Mizuno, Hiroaki Hojo, Masatomo Takahashi, Soshiro Kashio, Sora Enya, Motonao Nakao, Riyo Konishi, Mayuko Yoda, Ayano Harata, Junzo Hamanishi, Hiroshi Kawamoto, Masaki Mandai, Yutaka Suzuki, Masayuki Miura, Takeshi Bamba, Yoshihiro Izumi, Shinpei Kawaoka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The presence of cancer can induce systemic disruption of the host homeostasis. Here, the authors show that different solid tumours remotely increase hepatic nicotinamide-Nmethyltransferase disrupting the host urea cycle metabolism in the liver.
Externí odkaz:
https://doaj.org/article/f033da34790f4530b76d6f748729332a
Autor:
Chenfeng He, Riyo Konishi, Ayano Harata, Yuki Nakamura, Rin Mizuno, Mayuko Yoda, Masakazu Toi, Kosuke Kawaguchi, Shinpei Kawaoka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancers induce the production of acute phase proteins such as serum amyloid alpha (SAA) in the liver and cause inflammation in various host organs. Despite the well-known coincidence of acute phase response and inflammation, the direct roles of SAA p
Externí odkaz:
https://doaj.org/article/b820b60b7b35439286d7ca025972ba77
Publikováno v:
The Journal of Biochemistry.
Nicotinamide-N-methyltransferase (NNMT) is an enzyme that consumes S-adenosyl-methionine (SAM) and nicotinamide (NAM) to produce S-adenosyl-homocysteine (SAH) and 1-methylnicotinamide (MNAM). How much NNMT contributes to the quantity regulation of th
Autor:
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
The spatially organized gene expression program within the liver specifies hepatocyte functions according to their relative distances to the bloodstream (i.e., zonation), contributing to liver homeostasis. Despite the knowledge that solid cancers rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6935d36c132083789941ea671213a8
https://doi.org/10.1101/2022.09.27.509354
https://doi.org/10.1101/2022.09.27.509354
Autor:
Chenfeng He, Riyo Konishi, Ayano Harata, Yuki Nakamura, Rin Mizuno, Mayuko Yoda, Masakazu Toi, Kosuke Kawaguchi, Shinpei Kawaoka
Cancers induce the production of acute phase proteins such as serum amyloid alpha (SAA) in the liver and cause systemic inflammation. Despite the well-known coincidence of acute phase response and systemic inflammation, the direct roles of SAA protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::facf2b3fae59e16c2f3557be25d1c116
https://doi.org/10.1101/2022.09.26.509617
https://doi.org/10.1101/2022.09.26.509617
Nicotinamide-N-methyltransferase (NNMT) is an enzyme that consumes S-adenosyl-methionine (SAM) and nicotinamide (NAM) to produce S-adenosyl-homocysteine (SAH) and 1-methylnicotinamide (MNAM). How much NNMT contributes to the quantity regulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3b899161d43a7c9472928fd406b473
https://doi.org/10.1101/2022.09.25.509348
https://doi.org/10.1101/2022.09.25.509348
Autor:
Rin Mizuno, Hiroaki Hojo, Masatomo Takahashi, Soshiro Kashio, Sora Enya, Motonao Nakao, Riyo Konishi, Mayuko Yoda, Ayano Harata, Junzo Hamanishi, Hiroshi Kawamoto, Masaki Mandai, Yutaka Suzuki, Masayuki Miura, Takeshi Bamba, Yoshihiro Izumi, Shinpei Kawaoka
Publikováno v:
Nature communications. 13(1)
Cancers disrupt host homeostasis in various manners but the identity of host factors underlying such disruption remains largely unknown. Here we show that nicotinamide-N-methyltransferase (NNMT) is a host factor that mediates metabolic dysfunction in
Autor:
Satoko Uda, Yukio Yamanishi, Toshihiro Higuchi, Tsuyoshi Terashima, Rin Mizuno, Tatsuya Higashi
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 42:1198-1202
IgG4-related disease (IgG4-RD) is a systemic disease that affects multiple organs and generates nodules or thickening. Discriminating these diseases from malignancy is important because glucocorticoid treatment is effective for patients with IgG4-RD.
Autor:
Stephen Jun Fei Chong1, Fen Zhu1, Dashevsky, Olga1, Rin Mizuno1, Lai, Jolin X. H.2, Hackett, Liam1, Ryan, Christine E.1, Collins, Mary C.1, Iorgulescu, J. Bryan1,3, Guièze, Romain1, Penailillo, Johany1,3, Carrasco, Ruben1,3, Yeonjoo C. Hwang4, Muñoz, Denise P.4, Bouhaddou, Mehdi5, Yaw Chyn Lim6, Catherine J. Wu1, Allan, John N.7, Furman, Richard R.7, Boon Cher Goh6
Publikováno v:
Journal of Clinical Investigation. 11/15/2023, Vol. 133 Issue 22, p1-20. 20p.