Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rimsha Bhatta"'
Autor:
Rimsha Bhatta, Joonsu Han, Yusheng Liu, Yang Bo, David Lee, Jiadiao Zhou, Yueji Wang, Erik Russell Nelson, Qian Chen, Xiaojia Shelly Zhang, Wael Hassaneen, Hua Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract As key mediators of cellular communication, extracellular vesicles (EVs) have been actively explored for diagnostic and therapeutic applications. However, effective methods to functionalize EVs and modulate the interaction between EVs and re
Externí odkaz:
https://doaj.org/article/1c90df93c61e4c4a8f557d9c5c8af599
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Dendritic cell (DC) vaccine was among the first FDA-approved cancer immunotherapies, but has been limited by the modest cytotoxic T lymphocyte (CTL) response and therapeutic efficacy. Here we report a facile metabolic labeling approach that
Externí odkaz:
https://doaj.org/article/f06180e285c4431180104e3c9d6fba11
Autor:
Yang Bo, Yueji Wang, Joonsu Han, Rimsha Bhatta, Yusheng Liu, Dhyanesh Baskaran, Jiadiao Zhou, Hua Wang
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 101020- (2024)
Surgery followed by adjuvant chemotherapy or radiation therapy remains the mainstream treatment for breast cancer in the clinic. However, cancer recurrence post surgery is still common. In view of the clinical practice that autologous fat tissue graf
Externí odkaz:
https://doaj.org/article/a4059de7475c4130aec6010d32a34a31
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chemoimmunotherapy that utilizes the immunomodulatory effect of chemotherapeutics has shown great promise for treating poorly immunogenic solid tumors. However, there remains a significant room for improving the synergy between chemotherapy and immun
Externí odkaz:
https://doaj.org/article/b3a38db6499842baa9734bacf0d562b6
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer immunotherapy has shifted the paradigm for cancer treatment in the past decade, but new immunotherapies enabling the effective treatment of solid tumors are still greatly demanded. Here we report a pore-forming hydrogel-based immunotherapy tha
Externí odkaz:
https://doaj.org/article/37a6577613bd4ce9bcb37d31f4f9e99d
Autor:
Yi Zhang, Jinsong Cui, Kuan-Yu Chen, Shanny Hsuan Kuo, Jaishree Sharma, Rimsha Bhatta, Zheng Liu, Austin Ellis-Mohr, Fufei An, Jiahui Li, Qian Chen, Kari D. Foss, Hua Wang, Yumeng Li, Annette M. McCoy, Gee W. Lau, Qing Cao
Publikováno v:
Science Advances. 9
The prevalence of orthopedic implants is increasing with an aging population. These patients are vulnerable to risks from periprosthetic infections and instrument failures. Here, we present a dual-functional smart polymer foil coating compatible with
Publikováno v:
Journal of Controlled Release. 347:164-174
Metabolic glycan labeling provides a facile yet powerful tool to install chemical tags to the cell membrane via metabolic glycoengineering processes of unnatural sugars. These cell-surface chemical tags can then mediate targeted conjugation of therap
Autor:
Joshua Tropp, Noel C. Bell, Rimsha Bhatta, Marco Bonizzoni, Erin R. Crater, Ian C. Johnson, Jason D. Azoulay, Michael H. Ihde
Publikováno v:
ACS Sensors. 5:1541-1547
Azo dyes are ubiquitous pollutants that contaminate water supplies and threaten human, biota, and ecosystem health. Their detection and discrimination are a considerable challenge owing to the numerous structural, chemical, and optical similarities b
Publikováno v:
Acta biomaterialia. 150
Tough hydrogel adhesives that consist of a robust gel network and can strongly adhere to wet tissues have shown great promise as the next generation of bioadhesives. While a variety of chemistries can be utilized to construct the tough gel network, t
T cell-responsive macroporous hydrogels for in situ T cell expansion and enhanced antitumor efficacy
Publikováno v:
Biomaterials. 293:121972
Adoptive T cell therapy has demonstrated great promise for treating cancer and other diseases. While extensive effort has been made to improve ex vivo expansion of T cells, strategies for maintaining the proliferation and function of T cells post ado