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Akademický článek

Per- and polyfluoroalkyl substances, apolipoproteins and the risk of coronary heart disease in US men and women

Autor: Lu Zhu, Binkai Liu, Yang Hu, Molin Wang, Jeremy D. Furtado, Eric B. Rimm, Philippe Grandjean, Qi Sun

Publikováno v: Environmental Health, Vol 23, Iss 1, Pp 1-11 (2024)

Abstract Background Existing evidence for associations of per- and polyfluoroalkyl substances (PFASs) with blood lipids, lipoproteins and apolipoproteins (apo), and coronary heart disease (CHD) risk is limited and inconsistent. This study aims to exp

Externí odkaz: https://doaj.org/article/7ebb929ada3a4db3ad411332f6614abe

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Akademický článek

The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study

Autor: A. S. Carew, R. A. Warren, M. P. Bancks, M. A. Espeland, J. L. Bahnson, C. L. Lewis, A. P. Levy, J. L. Sapp, R. Urquhart, J. L. Wang, E. B. Rimm, L. E. Cahill

Publikováno v: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)

Abstract Background In the ACCORD study, participants with the haptoglobin (Hp) 2–2 phenotype and glycated hemoglobin (HbA1c) ≥ 8.0% had a higher risk of coronary artery disease (CAD) compared to those with HbA1c 7.0–7.9%. However, this associa

Externí odkaz: https://doaj.org/article/2bbd6ead508e43af963be028109a7b00

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Akademický článek

BCAM (basal cell adhesion molecule) protein expression in different tumor populations

Autor: Sneha Burela, Mengni He, Ioannis P. Trontzas, Niki Gavrielatou, Kurt A. Schalper, Solomon Langermann, Dallas B. Flies, David L. Rimm, Thazin N. Aung

Publikováno v: Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Basal Cell Adhesion Molecule (BCAM), a receptor for laminin subunit α5, plays a crucial role in the pathogenesis of various malignancies. Notably, evidence of hypermethylation at multiple immune checkpoints in patients with low BCAM express

Externí odkaz: https://doaj.org/article/e06f9eb926d740f08bba636b5ace8940

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Akademický článek

The analytical and clinical validity of AI algorithms to score TILs in TNBC: can we use different machine learning models interchangeably?Research in context

Autor: Joan Martínez Vidal, Nikos Tsiknakis, Johan Staaf, Ana Bosch, Anna Ehinger, Emma Nimeus, Roberto Salgado, Yalai Bai, David L. Rimm, Johan Hartman, Balazs Acs

Publikováno v: EClinicalMedicine, Vol 78, Iss , Pp 102928- (2024)

Summary: Background: Pathologist-read tumor-infiltrating lymphocytes (TILs) have showcased their predictive and prognostic potential for early and metastatic triple-negative breast cancer (TNBC) but it is still subject to variability. Artificial inte

Externí odkaz: https://doaj.org/article/0adae23c9c8543aebbd1a78749fbdeaa

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Akademický článek

Changes in fatty acid intake and subsequent risk of all-cause and cause-specific mortality in males and females: a prospective cohort study

Autor: Liu, Yuxi ^{1, 2}, Gu, Xiao ³, Li, Yanping ³, Rimm, Eric B ^{1, 2, 3}, Willett, Walter C ^{1, 2, 3}, Stampfer, Meir J ^{1, 2, 3}, Hu, Frank B ^{1, 2, 3, ⁎⁎}, Wang, Dong D ^{1, 3, ⁎}

Publikováno v: In The American Journal of Clinical Nutrition January 2025 121(1):141-150

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Akademický článek

Ultra-processed foods and cardiovascular disease: analysis of three large US prospective cohorts and a systematic review and meta-analysis of prospective cohort studiesResearch in context

Autor: Kenny Mendoza, Stephanie A. Smith-Warner, Sinara Laurini Rossato, Neha Khandpur, JoAnn E. Manson, Lu Qi, Eric B. Rimm, Kenneth J. Mukamal, Walter C. Willett, Molin Wang, Frank B. Hu, Josiemer Mattei, Qi Sun

Publikováno v: The Lancet Regional Health. Americas, Vol 37, Iss , Pp 100859- (2024)

Summary: Background: Prospective associations between total and groups of ultra-processed foods (UPF) and cardiovascular disease (CVD) remained to be characterised. Our aim was to assess the association of total and group-specific UPF intakes with CV

Externí odkaz: https://doaj.org/article/1a1b2694a34b449585468279a48d76ca

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Akademický článek

The analytical and clinical validity of AI algorithms to score TILs in TNBC: can we use different machine learning models interchangeably?

Autor: Vidal, Joan Martínez ^{a, l}, Tsiknakis, Nikos ^{a, l}, Staaf, Johan ^b, Bosch, Ana ^{b, c}, Ehinger, Anna ^d, Nimeus, Emma ^{b, e, f}, Salgado, Roberto ^{g, h}, Bai, Yalai ⁱ, Rimm, David L. ^{i, j}, Hartman, Johan ^{a, k}, Acs, Balazs ^{a, k, ∗}

Publikováno v: In eClinicalMedicine December 2024 78

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Akademický článek

An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk

Publikováno v: In Gastroenterology December 2024 167(7):1371-1383

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Akademický článek

Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study

Autor: Rachel A. Warren, Michael P. Bancks, Allie S. Carew, Andrew P. Levy, John Sapp, Judy Bahnson, Cora E. Lewis, Eric B. Rimm, Mark A. Espeland, Leah E. Cahill

Publikováno v: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)

Abstract Background Intensive glycemic control reduced coronary artery disease (CAD) events among the Action to Control Cardiovascular Disease Risk in Diabetes (ACCORD) participants with the haptoglobin (Hp) 2-2 phenotype only. It remains unknown whe

Externí odkaz: https://doaj.org/article/358ae63da8a0427890d2a30447e75293

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