Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rimjhim Agarwal"'
Autor:
Brian V Tsu, Rimjhim Agarwal, Nandan S Gokhale, Jessie Kulsuptrakul, Andrew P Ryan, Elizabeth J Fay, Lennice K Castro, Christopher Beierschmitt, Christina Yap, Elizabeth A Turcotte, Sofia E Delgado-Rodriguez, Russell E Vance, Jennifer L Hyde, Ram Savan, Patrick S Mitchell, Matthew D Daugherty
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002144 (2023)
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL protease (3CLpro) encoded by diverse c
Externí odkaz:
https://doaj.org/article/cdf5043f3dfb4817b3329b51ef3b0db4
Autor:
Glenn Oliveira, Chantal B F Vogels, Ashley Zolfaghari, Sharada Saraf, Raphaelle Klitting, James Weger-Lucarelli, Karla P Leon, Carlos O Ontiveros, Rimjhim Agarwal, Konstantin A Tsetsarkin, Eva Harris, Gregory D Ebel, Shirlee Wohl, Nathan D Grubaugh, Kristian G Andersen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 2, p e0011055 (2023)
RNA viruses have short generation times and high mutation rates, allowing them to undergo rapid molecular evolution during epidemics. However, the extent of RNA virus phenotypic evolution within epidemics and the resulting effects on fitness and viru
Externí odkaz:
https://doaj.org/article/453bfc6452a142fa8fc5e58577519836
Autor:
Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty
Publikováno v:
eLife, Vol 10 (2021)
The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains
Externí odkaz:
https://doaj.org/article/4a963c5b452f4d9c88a2a2ddfa16fdf1
Autor:
Onkar Nath, Stephen J. Fletcher, Alice Hayward, Lindsay M. Shaw, Rimjhim Agarwal, Agnelo Furtado, Robert J. Henry, Neena Mitter
Publikováno v:
Plants, Vol 11, Iss 3, p 242 (2022)
High-quality DNA and RNA forms the basis of genomic and genetic investigations. The extraction of DNA and RNA from woody trees, like avocado (Persea americana Mill.), is challenging due to compounds which interact with nucleic acids and influence sep
Externí odkaz:
https://doaj.org/article/bc638231a430419db268706a6ad9c636
Publikováno v:
Proceedings, Vol 36, Iss 1, p 161 (2020)
Zeaxanthin is a dietary carotenoid accumulated in the macula in order to reduce photoreceptor oxidation by blue light. Damage caused to photoreceptor cells in the human eye leads to macular degeneration, which is the leading cause of blindness in dev
Externí odkaz:
https://doaj.org/article/1d7342876f7d41debf78518bb83880d9
Autor:
Brian V. Tsu, Rimjhim Agarwal, Nandan S. Gokhale, Jessie Kulsuptrakul, Andrew P. Ryan, Lennice K. Castro, Christopher M. Beierschmitt, Elizabeth A. Turcotte, Elizabeth J. Fay, Russell E. Vance, Jennifer L. Hyde, Ram Savan, Patrick S. Mitchell, Matthew D. Daugherty
Hosts have evolved diverse strategies to respond to microbial infections, including the detection of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and CARD8. Here, we find that the 3CL protease (3CLpro) encoded by diverse c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60961e6666e00b8cd2dfdf2b6cf1f3f9
https://doi.org/10.1101/2022.09.21.508960
https://doi.org/10.1101/2022.09.21.508960
Publikováno v:
Journal of Alzheimer's disease : JAD. 88(s1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b665050d07bdc6c423a916596ddf27df
https://pubmed.ncbi.nlm.nih.gov/35912750
https://pubmed.ncbi.nlm.nih.gov/35912750
Autor:
Onkar Nath, Stephen J. Fletcher, Alice Hayward, Lindsay M. Shaw, Rimjhim Agarwal, Agnelo Furtado, Robert J. Henry, Neena Mitter
Publikováno v:
Plants, Vol 11, Iss 242, p 242 (2022)
High-quality DNA and RNA forms the basis of genomic and genetic investigations. The extraction of DNA and RNA from woody trees, like avocado (Persea americana Mill.), is challenging due to compounds which interact with nucleic acids and influence sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d21336f4d3643b69bae5fcd3a87453
https://pubmed.ncbi.nlm.nih.gov/35161230
https://pubmed.ncbi.nlm.nih.gov/35161230
Autor:
Christopher Beierschmitt, Andrew P. Ryan, Matthew D. Daugherty, Patrick S. Mitchell, Brian V Tsu, Rimjhim Agarwal
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c020eebd4181be5f5644c745cf4892
https://elifesciences.org/articles/60609
https://elifesciences.org/articles/60609