Tobacco Smoking Results in Reduced Pancreatic Islet Mass in Humans

Autor: Thomas Hubert, Valery Gmyr, Marie-Christine Vantyghem, François Pattou, Mehdi Daoudi, Rimed Ezzouaoui, Dorothée Thuillier, Mikael Chetboun, Julie Kerr-Conte, Violeta Raverdy, Antonino Bongiovanni

Publikováno v: Diabetes. 67

Epidemiological studies identify tobacco as an independent risk factor for T2D, however, the mechanisms involved remains unclear. Clinical studies incriminate an increase of insulin resistance but a direct effect on pancreatic islet mass is suggested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::868efab483e1e5a465d85a026bc6e2ce
https://doi.org/10.2337/db18-2143-p

Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial

Autor: Yvan Bricault, Gwen Grguric, Valery Gmyr, Eric Renard, Mathieu Rodière, Bruno Guerci, M. Greget, Anaïck Moisan, François Pattou, Cyrille Colin, Sophie Logerot, François Moreau, Frédéric Thony, Jean-Luc Bosson, C. Thivolet, Marie-Ange Pierredon, Sandrine Lablanche, Nadine Pernin, Kanza Benomar, Anne Wojtusciszyn, Jean Champagnac, Béatrice Roche, Christian Noel, Julie Kerr-Conte, Kristina Skaare, Violetta Raverdy, Pierre-Jean Valette, Kristel Le Mapihan, Christian Sengel, Fanny Buron, Thibault Bahoune, Igor Tauveron, Iulian Enescu, Arnaud Muller, Lionel Badet, Virginie Persoons, Marie-Christine Vantyghem, Marc Hazzan, Lucy Chaillous, Thierry Berney, Emmanuel Morelon, Rimed Ezzouaoui, R. Caiazzo, Sophie Borot, Domenico Bosco, Jacques Dantal, Laurence Kessler, Fanelly Torres, Paolo Malvezzi, Pierre-Yves Benhamou, Philippe Baltzinger, Coralie Camillo-Brault, Luc Frimat, Sophie Girerd, Alfred Penfornis, Harald Egelhofer, Jean-Pierre Riveline, Pierre Cattan, Rachel Tetaz

Publikováno v: Lancet Diabetes and Endocrinology
Lancet Diabetes and Endocrinology, Elsevier, 2018, 6 (7), pp.527--537. ⟨10.1016/S2213-8587(18)30078-0⟩
The Lancet Diabetes & Endocrinology (2018)

International audience; Background Islet transplantation is indicated for patients with type 1 diabetes with severe hypoglycaemia or after kidney transplantation. We did a randomised trial to assess the efficacy and safety of islet transplantation co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2114836f1462613d8617b59a2f620d
https://pubmed.ncbi.nlm.nih.gov/29776896

Human islet distribution programme for basic research: activity over the last 5 years

Autor: Alessia Mercalli, Marie Karlsson, Rita Nano, Lorenzo Piemonti, Domenico Bosco, François Pattou, Raffaella Melzi, Julie Kerr-Conte, Olle Korsgren, Albert Hwa, Thierry Berney, Rimed Ezzouaoui, Solange Charvier

Publikováno v: Diabetologia, Vol. 58, No 5 (2015) pp. 1138-40

To the Editor: Single-centre or collaborative efforts have been made to provide human pancreatic islets for use in basic science research. These include the Integrated Islet Distribution Program in the USA [1], the Human Islet Distribution Program fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313bc78226db95854fa0deed1fb51f5e
https://pubmed.ncbi.nlm.nih.gov/25697163

Production in vitro d’îlots pancréatiques humains à partir de cellules souches pluripotentes induites

Autor: Julien Thevenet, François Pattou, Rimed Ezzouaoui, Julie Kerr-Conte, Gianni Pasquetti, Alix Vaissie, Thomas Hubert, Audrey Quenon

Publikováno v: Diabetes & Metabolism. 43:A43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac3a49c63b723c3b881ba84480eb1c18
https://doi.org/10.1016/s1262-3636(17)30225-2

Automated Digital Image Analysis of islet cell mass using Nikon's inverted Eclipse Ti microscope and software to improve engraftment may help to advance the therapeutic efficacy and accessibility of islet transplantation across centers

Autor: Valery Gmyr, Caroline Bonner, Bruno Lukowiak, Valerie Pawlowski, Nathalie Dellaleau, Sandrine Belaich, Isanga Aluka, Ericka Moermann, Julien Thevenet, Rimed Ezzouaoui, Gurvan Queniat, Francois Pattou, Julie Kerr conte

Publikováno v: Cell Transplantation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0445c04ff32385b43aabe25cfffdbc26
https://doi.org/10.3727/096368913x663514