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Akademický článek

Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection.

Autor: Assia Samri, Charlotte Charpentier, Mariama Sadjo Diallo, Mélanie Bertine, Sophie Even, Véronique Morin, Anne Oudin, Christophe Parizot, Gilles Collin, Anne Hosmalin, Rémi Cheynier, Rodolphe Thiébaut, Sophie Matheron, Fideline Collin, Rima Zoorob, Françoise Brun-Vézinet, Brigitte Autran, ANRS CO5 IMMUNOVIR-2 Study Group

Publikováno v: PLoS Pathogens, Vol 15, Iss 5, p e1007758 (2019)

The low pathogenicity and replicative potential of HIV-2 are still poorly understood. We investigated whether HIV-2 reservoirs might follow the peculiar distribution reported in models of attenuated HIV-1/SIV infections, i.e. limited infection of cen

Externí odkaz: https://doaj.org/article/4eeff6c2de9446fb8a183892a8d380c6

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Akademický článek

Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.

Publikováno v: PLoS Genetics, Vol 10, Iss 6, p e1004417 (2014)

Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation. In humans, a fixed number of butyrophilin genes are fou

Externí odkaz: https://doaj.org/article/3bfc5bb7c6274a4188c491bf17d47bc0

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Treatment intensification followed by interleukin-7 reactivates HIV without reducing total HIV DNA

Autor: Francois Lecardonnel, Sidonie Lambert-Niclot, M Youle, Bonaventura Clotet, Robert L. Murphy, Vincent Calvez, Lambert Assoumou, Dominique Costagliola, Rima Zoorob, Laura Papagno, Chad J. Achenbach, Christine Katlama, Giuseppe Tambussi, Brigitte Autran

Publikováno v: AIDS. 30:221-230

As a first step towards HIV cure, we assessed a strategy of antiretroviral therapy (ART) intensification followed by interleukin-7 (IL-7) used as an HIV-reactivating agent.A multicentre, randomized clinical trial included patients on suppressive ART

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f41363bbacf3ede0c1be36a6e458e0
https://doi.org/10.1097/qad.0000000000000894

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Ultraviolet light converts propranolol, a nonselective β-blocker and potential lupus-inducing drug, into a proinflammatory AhR ligand

Autor: Hans Yssel, Alexis Mathian, Christophe Parizot, Laurent Arnaud, Sandra Pinto, Cédric Pionneau, Rima Zoorob, Karim Dorgham, Camille Francès, Martin Larsen, Makoto Miyara, Guy Gorochov, Hervé Devilliers, Zahir Amoura

Publikováno v: European Journal of Immunology. 45:3174-3187

UV light and some medications are known to trigger lupus erythematosus (LE). A common mechanism underlying the immunopathologic effect, resulting from exposure to these two seemingly unrelated factors, remains unknown. The aryl hydrocarbon receptor (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd1d429236d5ef9d72f9324cfc8c2802
https://doi.org/10.1002/eji.201445144

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Hepatitis C virus drives increased type I interferon-associated impairments associated with fibrosis severity in antiretroviral treatment-treated HIV-1-hepatitis C virus-coinfected individuals

Autor: Brigitte Autran, Marcus Altfeld, Christine Katlama, Zineb Sbihi, Karine Lacombe, Marguerite Guiguet, Morgane Griesbeck, Rima Zoorob, Julie Bottero, Assia Samri-Hassimi, Catherine Blanc, Marc-Antoine Valantin

Publikováno v: HIV/AIDS surveillance report (Atlanta, Ga.)
HIV/AIDS surveillance report (Atlanta, Ga.), 2017, ⟨10.1097/QAD.0000000000001455⟩

Background: Viral coinfections might contribute to the increased immune activation and inflammation that persist in antiretroviral treatment (ART)-treated HIV-1 patients. We investigated whether the hepatitis C virus (HCV) coinfection contributes to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f458eaece45104b44ea2499cb4b7c5f
https://hal.sorbonne-universite.fr/hal-02548458

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Blimp-1 overexpression is associated with low HIV-1 reservoir and transcription levels in central memory CD4+ T cells from elite controllers

Autor: Brigitte Autran, Amos Kirilovsky, Christine Rouzioux, Adèle de Masson, Rima Zoorob, Véronique Morin, Anne Oudin, Véronique Avettand-Fenoel, Benjamin Descours

Publikováno v: AIDS. 28:1567-1577

Objectives: The aim of the study was to determine the molecular mechanisms underlying the quasi-equilibrium between HIV and its host in the model of functional cure represented by elite controllers who spontaneously maintain exceptionally low levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4147e9e73187e41ce9b6a56942f750ae
https://doi.org/10.1097/qad.0000000000000295

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The hsa-miR-125a/hsa-let-7e/hsa-miR-99b cluster is potentially implicated in Cystic Fibrosis pathogenesis

Autor: Isabelle Sermet-Gaudelus, Thierry Bienvenu, Marie-Laure Endale Ahanda, Noélie Davezac, Laurent Mazzolini, Aleksander Edelman, Rima Zoorob

Publikováno v: Journal of Cystic Fibrosis
Journal of Cystic Fibrosis, Elsevier, 2015, 14 (5), pp.571-579. ⟨10.1016/j.jcf.2015.02.011⟩
Journal of Cystic Fibrosis, Elsevier, 2015, 14 (5), pp.571-579. 〈10.1016/j.jcf.2015.02.011〉

Background Cystic Fibrosis (CF) is an autosomal recessive disorder implicating the Cystic Fibrosis Transmembrane Regulator (CFTR). Even though CF is mainly considered an inherited monogenic disease, numerous findings over the last few years argue for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010956cc79e78eab836a7c3bdac21ead
https://hal.archives-ouvertes.fr/hal-01536521

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Cloning and Characterization of Chicken IL-10 and Its Role in the Immune Response to Eimeria maxima

Autor: John R. Young, Rima Zoorob, Adrian Smith, Pat Hesketh, Andrew Archer, Catherine A. Whittaker, Peter K. Kaiser, Lisa Rothwell

Publikováno v: The Journal of Immunology. 173:2675-2682

We isolated the full-length chicken IL-10 (chIL-10) cDNA from an expressed sequence tag library derived from RNA from cecal tonsils of Eimeria tenella-infected chickens. It encodes a 178-aa polypeptide, with a predicted 162-aa mature peptide. Chicken

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001748cd2c46808d3c1cad73840f173c
https://doi.org/10.4049/jimmunol.173.4.2675

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Diversity of Mhc class�I and IIB genes in house sparrows ( Passer domesticus )

Autor: Camille Bonneaud, Håkan Wittzell, Helena Westerdahl, Véronique Morin, Rima Zoorob, Gabriele Sorci

Publikováno v: Immunogenetics. 55:855-865

In order to understand the expression and evolution of host resistance to pathogens, we need to examine the links between genetic variability at the major histocompatibility complex ( Mhc), phenotypic expression of the immune response and parasite re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242a944443cb306b4a081c6ea0722623
https://doi.org/10.1007/s00251-004-0648-3

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Role of nonclassical class I genes of the chicken major histocompatibility complex Rfp-Y locus in transplantation immunity

Autor: Rima Zoorob, Ginette Dambrine, Anne-Marie Chaussé, Pierrick Thoraval, Marcia M. Miller, Denis Soubieux, Marielle Afanassieff, Evelyne Esnault, Gillette Luneau, Danièle Bouret, Ronald M. Goto

Publikováno v: Immunogenetics
Immunogenetics, Springer Verlag, 2003, 55, pp.647-651
Immunogenetics, 2003, 55, pp.647-651

The chicken major histocompatibility complex ( MHC) genes are organized into two genetically independent clusters which both possess class I and class IIbeta genes: the classical B complex and the Restriction fragment pattern- Y ( Rfp-Y) complex. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb21a0cb52931d8d694aa3b3807c2d9
https://doi.org/10.1007/s00251-003-0618-1

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