Výsledky vyhledávání - "Rima M. Sakhawala"

Akademický článek

Mechanism of RNA polymerase III termination-associated reinitiation-recycling conferred by the essential function of the N terminal-and-linker domain of the C11 subunit

Autor: Saurabh Mishra, Shaina H. Hasan, Rima M. Sakhawala, Shereen Chaudhry, Richard J. Maraia

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

RNA polymerase III (Pol III) employs termination-associated reinitiation-recycling to express high amounts of tRNAs, which involves the essential C11 subunit. Here the authors determine the functions of various C11 domains, finding that the N-termina

Externí odkaz: https://doaj.org/article/d8cf6ad2d84848129d410b1e12371186

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Akademický článek

Identification of Essential Genes and Fluconazole Susceptibility Genes in Candida glabrata by Profiling Hermes Transposon Insertions

Autor: Andrew N. Gale, Rima M. Sakhawala, Anton Levitan, Roded Sharan, Judith Berman, Winston Timp, Kyle W. Cunningham

Publikováno v: G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3859-3870 (2020)

Externí odkaz: https://doaj.org/article/7a8952b884d4442c96ee94d5eff3e67f

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The catalytic activity of microRNA Argonautes plays a modest role in microRNA star strand cleavage in C. elegans

Autor: Kasuen Kotagama, Acadia L. Grimme, Bing Yang, Rima M. Sakhawala, Guoyun Yu, Katherine McJunkin

Publikováno v: bioRxiv

Many Argonaute proteins can cleave RNA (“slicing”) as part of the microRNA-induced silencing complex (miRISC), even though miRNA-mediated target repression is generally independent of target cleavage. Here we useC. elegansto examine the role of m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3f29feb7ee640ea795e791898b6e93
https://europepmc.org/articles/PMC9882359/

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Identification of Essential Genes and Fluconazole Susceptibility Genes inCandida glabrataby ProfilingHermesTransposon Insertions

Autor: Andrew N. Gale, Kyle W. Cunningham, Winston Timp, Rima M. Sakhawala, Anton Levitan, Judith Berman, Roded Sharan

Publikováno v: G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3859-3870 (2020)
G3: Genes|Genomes|Genetics

Within the budding yeasts, the opportunistic pathogen Candida glabrata and other members of the Nakaseomyces clade have developed virulence traits independently from C. albicans and C. auris. To begin exploring the genetic basis of C. glabrata virule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adca245ca30e46c3094ae8c944601372
https://doi.org/10.1534/g3.120.401595

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Mechanism of RNA polymerase III termination-associated reinitiation-recycling conferred by the essential function of the N terminal-and-linker domain of the C11 subunit

Autor: Shaina H. Hasan, Shereen Chaudhry, Saurabh Mishra, Richard J. Maraia, Rima M. Sakhawala

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

RNA polymerase III achieves high level tRNA synthesis by termination-associated reinitiation-recycling that involves the essential C11 subunit and heterodimeric C37/53. The C11-CTD (C-terminal domain) promotes Pol III active center-intrinsic RNA 3′

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771bbaed39b7b3d070aefee1f7b79517
https://doi.org/10.1038/s41467-021-26080-7

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Identification of essential genes and fluconazole resistance genes inCandida glabrataby profiling ofHermestransposon insertions

Autor: Andrew N. Gale, Judith Berman, Anton Levitan, Roded Sharan, Winston Timp, Rima M. Sakhawala, Kyle W. Cunningham

Within the budding yeasts, the opportunistic pathogenCandida glabrataand other members of theNakaseomycesclade have developed virulence traits independently from the CTG clade that includesCandida albicans. To begin exploring the genetic basis ofC. g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b9f8b178ceb519fc51901913b89125
https://doi.org/10.1101/2020.04.27.064048

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