From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma

Autor: Joseph Lykins, Matthew J. Moschitto, Ying Zhou, Ekaterina V. Filippova, Hoang V. Le, Tadakimi Tomita, Barbara A. Fox, David J. Bzik, Chunlei Su, Seesandra V. Rajagopala, Kristin Flores, Furio Spano, Stuart Woods, Craig W. Roberts, Cong Hua, Kamal El Bissati, Kelsey M. Wheeler, Sarah Dovgin, Stephen P. Muench, Martin McPhillie, Colin W.G. Fishwick, Wayne F. Anderson, Patricia J. Lee, Mark Hickman, Louis M. Weiss, Jitender P. Dubey, Hernan A. Lorenzi, Richard B. Silverman, Rima L. McLeod

Publikováno v: iScience, Vol 27, Iss 1, Pp 108477- (2024)

Summary: Toxoplasma gondii causes morbidity, mortality, and disseminates widely via cat sexual stages. Here, we find T. gondii ornithine aminotransferase (OAT) is conserved across phyla. We solve TgO/GABA-AT structures with bound inactivators at 1.55

Externí odkaz: https://doaj.org/article/4214ce2e3d344bdb89d711a4b2786ce4

CONTRIBUTORS

Autor: John G. Aaskov, Susan M. Abdel-Rahman, Christoph Aebi, Marvin E. Ament, Marsha S. Anderson, Stephen S. Arnon, Ann M. Arvin, Jane T. Atkins, Robert L. Atmar, Carol J. Baker, Robert S. Baltimore, Stephen J. Barenkamp, Elizabeth D. Barnett, Robert D. Basow, William R. Beisel, Beth P. Bell, Gil Benard, David I. Bernstein, Kathrin M. Bernt, Andrea A. Berry, Charles D. Bluestone, Jeffrey L. Blumer, Robert Bortolussi, Bobby L. Boyanton, Kenneth M. Boyer, John S. Bradley, Michael T. Brady, William J. Britt, Annemarie Broderick, David E. Bronstein, David A. Bruckner, Steven C. Buckingham, Ana Burgos, Carrie L. Byington, Judith R. Campbell, Samson Cantu, Mariam R. Chacko, Louisa E. Chapman, Rémi N. Charrel, Tempe K. Chen, James D. Cherry, P. Joan Chesney, Madhuri C. Chilakapati, Javier Chinen, Natascha Ching, H. Fred Clark, Thomas G. Cleary, David K. Coats, Armando G. Correa, J. Thomas Cross, William B. Cutrer, Ronald Dagan, David E. Dassey, Jeffrey P. Davis, Gail J. Demmler-Harrison, Penelope H. Dennehy, Minh L. Doan, Simon R. Dobson, Jan E. Drutz, Paul H. Edelstein, Kathryn M. Edwards, Morven S. Edwards, B. Keith English, Dora Estripeaut, Leland L. Fan, Ralph D. Feigin, George D. Ferry, Anthony E. Fiore, Philip R. Fischer, Randall G. Fisher, Patricia M. Flynn, Thomas R. Flynn, Lisa M. Frenkel, Ellen M. Friedman, Richard A. Friedman, Lynne S. Garcia, Patrick J. Gavin, Michael A. Gerber, Anne A. Gershon, Mark A. Gilger, Susan L. Gillespie, Daniel G. Glaze, W. Paul Glezen, Mary P. Glodé, Donald A. Goldmann, Ellie J.C. Goldstein, Nira A. Goldstein, Edmond T. Gonzales, Mark P. Gorman, Michael D. Green, David Greenberg, Andreas H. Groll, Charles Grose, Duane J. Gubler, Roberto A. Guerrero, Javier Nieto Guevara, Kathleen M. Gutierrez, Caroline Breese Hall, Scott B. Halstead, Shinjiro Hamano, Richard J. Hamill, Margaret R. Hammerschlag, I. Celine Hanson, Nada Harik, Rick E. Harrison, C. Mary Healy, Ulrich Heininger, Gloria P. Heresi, Peter W. Hiatt, Harry R. Hill, David C. Hilmers, Jill A. Hoffman, Ellis K.L. Hon, Margaret K. Hostetter, Peter J. Hotez, Walter T. Hughes, Kristina G. Hulten, David A. Hunstad, Eugene S. Hurwitz, W. Charles Huskins, David Y. Hyun, Mary Anne Jackson, Michael R. Jacobs, Richard F. Jacobs, Jenifer L. Jaeger, Ravi R. Jhaveri, Samantha Johnston, Maureen M. Jonas, Meena R. Julapalli, Edward L. Kaplan, Sheldon L. Kaplan, Saul J. Karpen, Gregory L. Kearns, Margaret A. Keller, Chaouki K. Khoury, Martin B. Kleiman, Jerome O. Klein, Mark W. Kline, Katherine M. Knapp, Heidi M. Kokkinos, Peter J. Krause, Leonard R. Krilov, Paul Krogstad, Thomas L. Kuhls, Xavier de Lamballerie, Timothy R. La Pine, Matthew B. Laurens, Charles T. Leach, Robert J. Leggiadro, Diana R. Lennon, Carolyn Lentzsch-Parcells, Eric Leroy, Chi Wai Leung, Moise L. Levy, Karen Lewis, Phyllis T. Losikoff, Timothy Edward Lotze, Adam W. Lowry, Timothy Mailman, Susan A. Maloney, Laurene Mascola, Edward O. Mason, David O. Matson, Alan N. Mayer, Marc A. Mazade, James B. McAuley, George H. McCracken, Kenneth McIntosh, James E. McJunkin, Kelly T. McKee, Rima L. McLeod, Valérie A. McLin, Maria José Soares Mendes-Giannini, Wayne M. Meyers, Marian G. Michaels, Ian C. Michelow, Vladana Milisavljevic, Aaron M. Miller, James N. Miller, Marjorie J. Miller, James N. Mills, Linda L. Minnich, Ann Moran, James R. Murphy, Pratip K. Nag, Joseph J. Nania, James P. Nataro, Roger K. Nicome, Karin Nielsen-Saines, Delma J. Nieves, Richard A. Oberhelman, Theresa J. Ochoa, Christopher M. Oermann, Alina Olteanu, Gary D. Overturf, Debra L. Palazzi, Pia S. Pannaraj, Janak A. Patel, Christian C. Patrick, Evelyn A. Paysse, Norma Pérez, C.J. Peters, William A. Petri, Brandon Lane Phillips, Larry K. Pickering, Joseph F. Piecuch, Francisco P. Pinheiro, Stanley A. Plotkin, Scott L. Pomeroy, Alice Pong, David L. Pugatch, Joan S. Purcell, Ramya Ramraj, Jack S. Remington, Carina A. Rodriguez, José R. Romero, Benjamin A. Ross, Lawrence A. Ross, Judith L. Rowen, Charles E. Rupprecht, Xavier Sáez-Llorens, Lisa Saiman, Joseph W. St. Geme, Pablo J. Sánchez, Laura A. Sass, Carlos A. Sattler, Danica J. Schulte, Gordon E. Schutze, Filiz O. Seeborg, Eugene D. Shapiro, Nina L. Shapiro, William T. Shearer, Ziad M. Shehab, Jerry L. Shenep, W. Donald Shields, Robyn Shimizu-Cohen, Stanford T. Shulman, Constantine Simos, Arnold L. Smith, Jason S. Soden, Mary Allen Staat, Jeffrey R. Starke, Barbara W. Stechenberg, William J. Steinbach, Paul G. Steinkuller, E. Richard Stiehm, Stephanie H. Stovall, Jeffrey Suen, Ciro V. Sumaya, Andrea P. Summer, Douglas S. Swanson, Tina Q. Tan, Herbert B. Tanowitz, Robert B. Tesh, Philip Toltzis, Richard G. Topazian, Michael F. Tosi, Amelia P.A. Travassos da Rosa, Theodore F. Tsai, Tulio A. Valdez, Jesus G. Vallejo, John A. Vanchiere, Pedro Fernando da C. Vasconcelos, Jorge J. Velarde, James Versalovic, Ellen R. Wald, Douglas S. Walsh, Edward E. Walsh, Thomas J. Walsh, Mark A. Ward, Richard L. Ward, Michelle Weinberg, Robert C. Welliver, J. Gary Wheeler, A. Clinton White, Suzanne Whitworth, Bernhard L. Wiedermann, Natalie Williams-Bouyer, Murray Wittner, Charles R. Woods, Kimberly G. Yen, Ram Yogev, Edward J. Young, Theoklis E. Zaoutis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::776f30bfa13237303e7ea9778675d741
https://doi.org/10.1016/b978-1-4160-4044-6.50004-2