Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rima Kulikauskas"'
Autor:
Shailender Bhatia, Paul Nghiem, Rima Kulikauskas, Candice Church, David M Koelle, Lisa Tachiki, Kimberly Smythe, Thomas Pulliam, Shira Tabachnick-Cherny, Saumya Jani, Peter H Goff, Rashmi Bhakuni, Brandon W Seaton
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background Antibodies blocking programmed death (PD)-1 or its ligand (PD-L1) have revolutionized cancer care, but many patients do not experience durable benefits. Novel treatments to stimulate antitumor immunity are needed in the PD-(L)1 refractory
Externí odkaz:
https://doaj.org/article/5d97ea745ca64b74a14af5ba8a97b20b
Autor:
Paul Nghiem, Rima Kulikauskas, Daniel S Hippe, Xinyi Fan, Kimberly S Smythe, Ata Moshiri, Thomas Pulliam, Shira Tabachnick-Cherny, Haroldo Rodriguez Chevez, Kelly Paulson, Daniel C Jones, Lisa Zaba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/379ef1c1c29248a193df200a3e9215c4
Autor:
Natalie J. Miller, Candice D. Church, Steven P. Fling, Rima Kulikauskas, Nirasha Ramchurren, Michi M. Shinohara, Harriet M. Kluger, Shailender Bhatia, Lisa Lundgren, Martin A. Cheever, Suzanne L. Topalian, Paul Nghiem
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus (MCPyV). MCPyV-specific T and B cell respon
Externí odkaz:
https://doaj.org/article/e8021ab7a1ff40af8dd91b15754b2650
Autor:
Paul Nghiem, David M. Koelle, Frank J. Hsu, Jan ter Meulen, Rima Kulikauskas, Upendra Parvathaneni, David R. Byrd, Michi M. Shinohara, Dafina Ibrani, Natalie V. Longino, Hailing Lu, Natalie J. Miller, Shailender Bhatia
Table S2 lists immune-related genes with the greatest fold differences in induction between clinical responders versus non-responders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5234df97c0872c8bd3d5584e80777f63
https://doi.org/10.1158/1078-0432.22468199
https://doi.org/10.1158/1078-0432.22468199
Autor:
Paul Nghiem, David M. Koelle, Frank J. Hsu, Jan ter Meulen, Rima Kulikauskas, Upendra Parvathaneni, David R. Byrd, Michi M. Shinohara, Dafina Ibrani, Natalie V. Longino, Hailing Lu, Natalie J. Miller, Shailender Bhatia
Figure S3 shows quantification of new and induced TCR clones in tumor and blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045c041cafd24f9a86ee95bf68e7f3af
https://doi.org/10.1158/1078-0432.22468208
https://doi.org/10.1158/1078-0432.22468208
Autor:
Paul Nghiem, David M. Koelle, Frank J. Hsu, Jan ter Meulen, Rima Kulikauskas, Upendra Parvathaneni, David R. Byrd, Michi M. Shinohara, Dafina Ibrani, Natalie V. Longino, Hailing Lu, Natalie J. Miller, Shailender Bhatia
Purpose:G100 is a toll-like receptor 4 (TLR4) agonist that triggers innate and adaptive antitumor immune responses in preclinical models. This pilot study assessed the safety, efficacy, and immunologic activity of intratumoral (IT) administration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f22a219572129826090b7069cb07a03
https://doi.org/10.1158/1078-0432.c.6526865.v1
https://doi.org/10.1158/1078-0432.c.6526865.v1
Autor:
Paul Nghiem, Adil I. Daud, Richard Heller, Robert H. Pierce, Sharron Gargosky, Mai H. Le, Jean S. Campbell, Christopher G. Twitty, Upendra Parvathaneni, David R. Byrd, Astrid Blom, Dafina Ibrani, Jayasri G. Iyer, Rima Kulikauskas, Natalie J. Miller, Natalie V. Longino, Shailender Bhatia
Figure S1, Table S1, Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b89502ad3bb28bd2ecd97aed8b58f1
https://doi.org/10.1158/1078-0432.22473930
https://doi.org/10.1158/1078-0432.22473930
Autor:
Paul Nghiem, Adil I. Daud, Richard Heller, Robert H. Pierce, Sharron Gargosky, Mai H. Le, Jean S. Campbell, Christopher G. Twitty, Upendra Parvathaneni, David R. Byrd, Astrid Blom, Dafina Ibrani, Jayasri G. Iyer, Rima Kulikauskas, Natalie J. Miller, Natalie V. Longino, Shailender Bhatia
Purpose:IL12 promotes adaptive type I immunity and has demonstrated antitumor efficacy, but systemic administration leads to severe adverse events (AE), including death. This pilot trial investigated safety, efficacy, and immunologic activity of intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204e536846077c7c84f51921ed778e5a
https://doi.org/10.1158/1078-0432.c.6528642.v1
https://doi.org/10.1158/1078-0432.c.6528642.v1
Autor:
Thomas Pulliam, Saumya Jani, Lichen Jing, Jiajia Zhang, Rima Kulikauskas, Candice Church, Charlie Garnett-Benson, Kelly Paulson, Kellie Smith, Andrew Pardoll, David Koelle, Suzanne Topalian, Paul Nghiem
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Shira Tabachnick-Cherny, Thomas Pulliam, Haroldo Rodriguez Chevez, Kimberly Smythe, Rima Kulikauskas, Kristina Lachance, Daniel Hippe, Paul Nghiem
Publikováno v:
Regular and Young Investigator Award Abstracts.