Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Rima Izem"'
Autor:
Kuntal Sen, Rima Izem, Yuelin Long, Jiji Jiang, Laura L. Konczal, Robert J. McCarter, Members of the Urea Cycle Disorders Consortium (UCDC), Andrea L. Gropman, Jirair K. Bedoyan
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Background Ornithine transcarbamylase deficiency (OTCD) due to an X‐linked OTC mutation, is responsible for moderate to severe hyperammonemia (HA) with substantial morbidity and mortality. About 80% of females with OTCD remain apparently
Externí odkaz:
https://doaj.org/article/ff12e2767c3c4f77888b31bc65408744
Autor:
Cartik Kothari, Siddharth Srivastava, Youssef Kousa, Rima Izem, Marcin Gierdalski, Dongkyu Kim, Amy Good, Kira A. Dies, Gregory Geisel, Hiroki Morizono, Vittorio Gallo, Scott L. Pomeroy, Gwenn A. Garden, Lisa Guay-Woodford, Mustafa Sahin, Paul Avillach
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-8 (2022)
Abstract Background Computational phenotypes are most often combinations of patient billing codes that are highly predictive of disease using electronic health records (EHR). In the case of rare diseases that can only be diagnosed by genetic testing,
Externí odkaz:
https://doaj.org/article/073fec6cc62f415fa02521360854397b
Autor:
Rima Izem, Robert McCarter
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract In the United States, approximately 7000 rare diseases affect 30 million patients, and only 10% of these diseases have existing therapies. Sound study design and causal inference methods are essential to demonstrate the therapeutic efficacy,
Externí odkaz:
https://doaj.org/article/9253ab0790f24de99be7790223c1c8ff
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021)
Abstract Background Standard treatment for both uncomplicated and severe malaria is artemisinin derivatives. Delayed parasite clearance times preceded the appearance of artemisinin treatment failures in Southeast Asia. Most worldwide malaria cases ar
Externí odkaz:
https://doaj.org/article/5385f41aea7f46c08ed87e0eabea54bc
Publikováno v:
PLoS Biology, Vol 4, Iss 7, p e201 (2006)
Two major goals of laboratory evolution experiments are to integrate from genotype to phenotype to fitness, and to understand the genetic basis of adaptation in natural populations. Here we demonstrate that both goals are possible by re-examining the
Externí odkaz:
https://doaj.org/article/8ca09bc39b4341f790edc558e233ee1e
Autor:
Cindy D Colson, Emily C Alberto, Zachary P Milestone, Nikita Batra, Tyler Salvador, Hadi Fooladi, Kevin Cleary, Rima Izem, Randall S Burd
Publikováno v:
Emergency Medicine Journal. 40:279-284
BackgroundCurrent methods of burn estimation can lead to incorrect estimates of the total body surface area (TBSA) burned, especially among injured children. Inaccurate estimation of burn size can impact initial management, including unnecessary tran
Autor:
Mark Levenson, Weili He, Li Chen, Sai Dharmarajan, Rima Izem, Zhaoling Meng, Herbert Pang, Frank Rockhold
Publikováno v:
Statistics in Biopharmaceutical Research. :1-8
Publikováno v:
Therapeutic Innovation & Regulatory Science. 56:704-716
Real-world data (RWD) can contextualize findings from single-arm trials when randomized comparative trials are unethical or unfeasible. Findings from single-arm trials alone are difficult to interpret and a comparison, when feasible and meaningful, t
Autor:
Ariunzaya Amgalan, Kushal Kapse, Dhineshvikram Krishnamurthy, Nicole R. Andersen, Rima Izem, Ahmet Baschat, Jessica Quistorff, Alexis C. Gimovsky, Homa K. Ahmadzia, Catherine Limperopoulos, Nickie N. Andescavage
Publikováno v:
Journal of Perinatology. 42:860-865
The aim of this study was to determine in utero fetal-placental growth patterns using in vivo three-dimensional (3D) quantitative magnetic resonance imaging (qMRI).Healthy women with singleton pregnancies underwent fetal MRI to measure fetal body, pl
Autor:
Lisa V. Hampson, Rima Izem
Publikováno v:
Real-World Evidence in Medical Product Development ISBN: 9783031263279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1165cd4f5fab1b2134a0279a35134cde
https://doi.org/10.1007/978-3-031-26328-6_12
https://doi.org/10.1007/978-3-031-26328-6_12