Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rim S.J. Sarker"'
Autor:
Michael Bustin, Takashi Furusawa, Rim S.J. Sarker, Julian Dorer, Ali Önder Yildirim, Martin Hrabě de Angelis, Helmut Fuchs, Thomas M. Conlon, Gerald Burgstaller, Lisa Merthan, Valerie Gailus-Durner
Publikováno v:
Molecular pathology and funct. genomics.
A role for epigenetics in COPD susceptibility is emerging. We previously detected spontaneous emphysema development in HMGN5 deficient mice. HMGN5 binds to the nucleosomal core particle of chromatin, competing with histone H1, thus altering chromatin
Autor:
Thomas M. Conlon, Ali Önder Yildirim, Nur Konyalilar, Stijn E. Verleden, Barkha Srivastava, Rim S.J. Sarker, Heinz Fehrenbach, Hasan Bayram, Carmela Morrone
Publikováno v:
Am. J. Physiol. Lung Cell Mol. Physiol. 317, L602-L614 (2019)
American journal of physiology: lung cellular and molecular physiology
American journal of physiology: lung cellular and molecular physiology
Chronic obstructive pulmonary disease (COPD) is a life-threatening lung disease. Although cigarette smoke was considered the main cause of development, the heterogeneous nature of the disease leaves it unclear whether other factors contribute to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd300e3887cd9118026dd4b318268e8c
https://lirias.kuleuven.be/handle/123456789/640867
https://lirias.kuleuven.be/handle/123456789/640867
Autor:
G. Günes Günsel, Oliver Eickelberg, Demet Taşdemir, Hasan Bayram, Ali Önder Yildirim, Jie Jia, Thomas M. Conlon, Rim S.J. Sarker, Katharina Heinzelmann
Publikováno v:
C93. MECHANISMS OF AIRWAY INFLAMMATION IN ASTHMA AND COPD.
Autor:
Jie Jia, Ali Önder Yildirim, Martin Hrabé de Angelis, Jiaqi Gao, Jutta Lintelmann, Oliver Eickelberg, Rim S.J. Sarker, Katharina Heinzelmann, Martin Irmler, Cornelia Prehn, Ralf Zimmermann, Johannes Beckers, Jerzy Adamski, Natalia F. Smirnova, Thomas M. Conlon, Demet Taşdemir, Hasan Bayram, Gizem Gunes, Stijn E. Verleden, Barkha Srivastava, Xiao Wu, Stefan Pfeiffer, Michael Schloter
Publikováno v:
EMBO Molecular Medicine
EMBO molecular medicine
EMBO Mol. Med. 10:e8349 (2018)
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)
ResearcherID
EMBO molecular medicine
EMBO Mol. Med. 10:e8349 (2018)
EMBO Molecular Medicine, Vol 10, Iss 5, Pp n/a-n/a (2018)
ResearcherID
The development of chronic obstructive pulmonary disease (COPD) pathogenesis remains unclear, but emerging evidence supports a crucial role for inducible bronchus-associated lymphoid tissue (iBALT) in disease progression. Mechanisms underlying iBALT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805d51909d0e6a8b4440a41824323f89
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8006
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8006
Autor:
Ali Önder Yildirim, Michael Bustin, Julian Dorer, Helmut Fuchs, Martin Hrabě de Angelis, Gizem Gunes, Thomas M. Conlon, Rim S.J. Sarker, Oliver Eickelberg, Valerie Gailus-Durner, Takashi Furusawa, Gerald Burgstaller
Publikováno v:
Molecular Pathology and Functional Genomics.
COPD, characterized by chronic bronchitis, small airway remodeling and emphysema, is one of the leading causes of chronic morbidity and mortality worldwide. Chronic lung injury, commonly caused by cigarette smoking (CS), is a major factor in its deve
Autor:
Ali Önder Yildirim, Oliver Eickelberg, Kathrin Mutze, Gerrit John-Schuster, Alexander Bohla, Rim S.J. Sarker, Gerald Burgstaller, Mark T. Bedford, Melanie Königshoff
Chronic obstructive pulmonary disease (COPD) is characterized by an irreversible loss of lung function and is one of the most prevalent and severe diseases worldwide. A major feature of COPD is emphysema, which is the progressive loss of alveolar tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a74b8b0b124109c531a8bed2962900
https://europepmc.org/articles/PMC5455466/
https://europepmc.org/articles/PMC5455466/
Publikováno v:
Nature Communications. 6
An imbalance between neutrophil-derived proteases and extracellular inhibitors is widely regarded as an important pathogenic mechanism for lung injury. Despite intense efforts over the last three decades, attempts to develop small-molecule inhibitors