Zobrazeno 1 - 10 of 276 pro vyhledávání: '"Rim, Jung"'
1
Akademický článek
Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy
Autor: Yumi Oh, Sujeong Kim, Yunjae Kim, Hyun Kim, Dongjun Jang, Seungjae Shin, Soo-Jin Lee, Jiwon Kim, Sang Eun Lee, Jaeik Oh, Yoojin Yang, Dohee Kim, Hae Rim Jung, Sangjin Kim, Jihui Kim, Kyungchan Min, Beomki Cho, Hoseok Seo, Dohyun Han, Hansoo Park, Sung-Yup Cho
Publikováno v: Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Immune checkpoint therapy (ICT) provides durable responses in select cancer patients, yet resistance remains a significant challenge, prompting the exploration of underlying molecular mechanisms. Tyrosylprotein sulfotransferase-2
Externí odkaz: https://doaj.org/article/47974d639c9a4312819824b9409e4268
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2
Akademický článek
Targeting the m6A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis
Autor: Hae Rim Jung, Jeonghwan Lee, Seung-Pyo Hong, Nayeon Shin, Ara Cho, Dong-Jin Shin, Jin Woo Choi, Jong-Il Kim, Jung Pyo Lee, Sung-Yup Cho
Publikováno v: Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 355-369 (2024)
Abstract Kidney fibrosis is a major mechanism underlying chronic kidney disease (CKD). N6-methyladenosine (m6A) RNA methylation is associated with organ fibrosis. We investigated m6A profile alterations and the inhibitory effect of RNA methylation in
Externí odkaz: https://doaj.org/article/34b6126bb26c4cb491e8cafd82dfb565
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3
Akademický článek
In vivo imaging of invasive aspergillosis with 18F-fluorodeoxysorbitol positron emission tomography
Autor: Dong-Yeon Kim, Ayoung Pyo, Sehyeon Ji, Sung-Hwan You, Seong Eun Kim, Daejin Lim, Heejung Kim, Kyung-Hwa Lee, Se-Jeong Oh, Ye-rim Jung, Uh Jin Kim, Subin Jeon, Seong Young Kwon, Sae-Ryung Kang, Hyang Burm Lee, Hoon Hyun, So-Young Kim, Kyung-Sub Moon, Sunwoo Lee, Seung Ji Kang, Jung-Joon Min
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Current diagnostic methods for invasive aspergillosis are time-consuming and poorly sensitive. Here, the authors show that positron emission tomography with 2-deoxy-2-18F-fluorosorbitol can visualize Aspergillus fumigatus infection of the lungs, brai
Externí odkaz: https://doaj.org/article/e5d55bcc38b34c86af769de28ed3517d
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6
Akademický článek
Effects of a combination treatment of KD5040 and L-dopa in a mouse model of Parkinson’s disease
Autor: Sora Ahn, Taek-Jin Song, Seong-Uk Park, Songhee Jeon, Jongpil Kim, Joo-Young Oh, Jaehwan Jang, Sanhwa Hong, Min-A Song, Hye-Seoung Shin, Young-Rim Jung, Hi-Joon Park
Publikováno v: BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background Although the dopamine precursor L-3, 4-dihydroxyphenylalanine ( l -dopa) remains the gold standard pharmacological therapy for patients with Parkinson’s disease (PD), long-term treatment with this drug has been known to result i
Externí odkaz: https://doaj.org/article/8d47faec249047d4ba3a4a265ddb94a0
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