Centrally acting antihypertensives change the psychogenic cardiovascular reactivity.

Autor: Mendonça MM; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Costa AN; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Moraes GCA; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Martins GM; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Almeida AF; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Rincon GCN; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Siqueira JPR; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Padilha DM; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Moya MI; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.; School of Medicine, Federal University of Goias, Goiania, Brazil., Ferreira-Neto ML; Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlandia, Brazil., Gomes RM; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Pedrino GR; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Fontes MAP; Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil., Colombari E; School of Dentistry, São Paulo State University (UNESP), Araraquara, Brazil., Crestani CC; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil., Fajemiroye JO; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil., Xavier CH; Institute of Biological Sciences, Federal University of Goias, Goiania, Brazil.

Publikováno v: Fundamental & clinical pharmacology [Fundam Clin Pharmacol] 2021 Oct; Vol. 35 (5), pp. 892-905. Date of Electronic Publication: 2021 Feb 27.

Rilmenidine extends lifespan and healthspan in Caenorhabditis elegans via a nischarin I1-imidazoline receptor.

Autor: Bennett DF; Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK., Goyala A; Department of Health Sciences and Technology, Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, ETH Zürich, Schwerzenbach, Switzerland., Statzer C; Department of Health Sciences and Technology, Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, ETH Zürich, Schwerzenbach, Switzerland., Beckett CW; Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK., Tyshkovskiy A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia., Gladyshev VN; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ewald CY; Department of Health Sciences and Technology, Laboratory of Extracellular Matrix Regeneration, Institute of Translational Medicine, ETH Zürich, Schwerzenbach, Switzerland., de Magalhães JP; Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.

Publikováno v: Aging cell [Aging Cell] 2023 Feb; Vol. 22 (2), pp. e13774. Date of Electronic Publication: 2023 Jan 20.

Stimulation of mTOR-independent autophagy and mitophagy by rilmenidine exacerbates the phenotype of transgenic TDP-43 mice.

Autor: Perera ND; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Tomas D; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Wanniarachchillage N; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Cuic B; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Luikinga SJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Rytova V; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia., Turner BJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3052, Australia; Perron Institute for Neurological and Translational Science, Queen Elizabeth Medical Centre, Nedlands, Western Australia 6150, Australia. Electronic address: bradley.turner@florey.edu.au.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2021 Jul; Vol. 154, pp. 105359. Date of Electronic Publication: 2021 Mar 30.

Synergism of myocardial β-adrenoceptor blockade and I 1 -imidazoline receptor-driven signaling: Kinase-phosphatase switching.

Autor: Maltsev AV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow Region, Pushchino, Institutskaya, 3, 142290, Russia; Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Butlerova 5А, 117485, Russia. Electronic address: alex.v.maltsev88@gmail.com., Evdokimovskii EV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow Region, Pushchino, Institutskaya, 3, 142290, Russia., Kokoz YM; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow Region, Pushchino, Institutskaya, 3, 142290, Russia.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Apr 02; Vol. 511 (2), pp. 363-368. Date of Electronic Publication: 2019 Feb 19.

Mitochondrial dysfunction is associated with long-term cognitive impairment in an animal sepsis model.

Autor: Manfredini A; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Constantino L; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Pinto MC; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Michels M; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Burger H; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Kist LW; Genomics and Molecular Biology Laboratory, Faculty of Biosciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil.; Postgraduate Program in Medicine and Health Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil., Silva MC; Laboratory of Bioenergetics, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Gomes LM; Laboratory of Bioenergetics, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Dominguini D; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Steckert A; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Simioni C; Plant Cell Biology Laboratory, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil., Bogo M; Genomics and Molecular Biology Laboratory, Faculty of Biosciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil.; Postgraduate Program in Medicine and Health Sciences, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil., Streck E; Laboratory of Bioenergetics, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Barichello T; Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, U.S.A.; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, U.S.A.; Laboratory of Experimental Microbiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., de Quevedo J; Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, U.S.A.; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, U.S.A.; Neuroscience Graduate Program, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, U.S.A.; Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Singer M; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom., Ritter C; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil., Dal-Pizzol F; Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil fdpizzol@gmail.com.

Publikováno v: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2019 Sep 24; Vol. 133 (18), pp. 1993-2004. Date of Electronic Publication: 2019 Sep 24 (Print Publication: 2019).