Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Rilin Deng"'
Autor:
Luoling Wang, Rilin Deng, Shuishun Chen, Renyun Tian, Mengmeng Guo, Zihao Chen, Yingdan Zhang, Huiyi Li, Qian Liu, Songqing Tang, Haizhen Zhu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Pyroptosis, a mode of inflammatory cell death, has recently gained significant attention. However, the underlying mechanism remains poorly understood. HGS-ETR1/2 is a humanized monoclonal antibody that can bind to DR4/5 on the cell membrane
Externí odkaz:
https://doaj.org/article/552dec21a87b49dbbb3ee4330ed4c0ab
Autor:
Rilin Deng, Renyun Tian, Xinran Li, Yan Xu, Yongqi Li, Xintao Wang, Huiyi Li, Luoling Wang, Biaoming Xu, Di Yang, Songqing Tang, Binbin Xue, Chaohui Zuo, Haizhen Zhu
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109533- (2024)
Summary: Hepatitis B virus (HBV) infection generally elicits weak type-I interferon (IFN) immune response in hepatocytes, covering the regulatory effect of IFN-stimulated genes. In this study, low level of IFN-stimulated gene 12a (ISG12a) predicted m
Externí odkaz:
https://doaj.org/article/f9e56d66fe264bf1a9113a59729103da
Autor:
Qi Hu, Shuai Chen, Rilin Deng, Hongyu Deng, Mingjing Peng, Xiaohong Wang, Shun Deng, Jinfeng Wang, Biaoming Xu, Yan Xu, Haizhen Zhu, Jinhai Zheng, Man Xia, Chaohui Zuo
Publikováno v:
Analytical Cellular Pathology, Vol 2024 (2024)
Tumor microenvironment (TME) is essential for the development and progression of hepatocellular carcinoma (HCC). Exosomes participate in constructing TME by passing biological information, but the regulatory effect of PDL1 in exosomes on anticancer a
Externí odkaz:
https://doaj.org/article/d918e0baa26b4172ae62558f028ef972
Establishment of cell culture model and humanized mouse model of chronic hepatitis B virus infection
Autor:
Renyun Tian, Di Yang, Biaoming Xu, Rilin Deng, Binbin Xue, Luoling Wang, Huiyi Li, Qian Liu, Xiaohong Wang, Songqing Tang, Mengyu Wan, Hua Pei, Haizhen Zhu
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT The absence of a hepatitis B virus (HBV) infection system has constrained the study of the viral life cycle and the development of antiviral drugs. We previously established a hepatocellular carcinoma cell line, HLCZ01, that can support the
Externí odkaz:
https://doaj.org/article/a4f46cb1f9c74f99a063dbb8b71dd418
Autor:
Jinfeng Wang, Rilin Deng, Shuai Chen, Shun Deng, Qi Hu, Biaoming Xu, Junjun Li, Zhuo He, Mingjing Peng, Sanlin Lei, Tiexiang Ma, Zhuo Chen, Haizhen Zhu, Chaohui Zuo
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108414- (2023)
Summary: Cytotoxin-associated gene A (CagA) of Helicobacter pylori (Hp) may promote immune evasion of Hp-infected gastric cancer (GC), but potential mechanisms are still under explored. In this study, the positive rates of CagA and PD-L1 protein in t
Externí odkaz:
https://doaj.org/article/1f7e2b047ba94633977fb30008b03908
Autor:
Di Yang, Renyun Tian, Rilin Deng, Binbin Xue, Shun Liu, Luoling Wang, Huiyi Li, Qian Liu, Mengyu Wan, Songqing Tang, Xiaohong Wang, Haizhen Zhu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT KDM7A (lysine demethylase 7A, also known as JHDM1D) is a histone demethylase, it is mainly involved in the intracellular post-translational modifications process. Recently, it has been proved that the histone demethylase members can regulate
Externí odkaz:
https://doaj.org/article/78c2837d65714656a74b21b1e2f113a8
Autor:
Cong Wang, Xue Li, Binbin Xue, Changping Yu, Luoling Wang, Rilin Deng, Hui Liu, Zihao Chen, Yingdan Zhang, Suping Fan, Chaohui Zuo, Hungyu Sun, Haizhen Zhu, Jianli Wang, Songqing Tang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
IL-6 and RasGRP1 have been shown to have important functions during inflammation and cancer. Here the authors propose the protein and mRNA of RasGRP1 have opposing functions by promoting IL-6 mediated acute inflammation and inhibiting inflammation-as
Externí odkaz:
https://doaj.org/article/098097061bc2455c83e4dbd3720e5dc7
Autor:
Huiyi Li, Shun Liu, Qing Feng, Rilin Deng, Jingjing Wang, Xintao Wang, Renyun Tian, Yan Xu, Shengwen Chen, Qian Liu, Luoling Wang, Xinran Li, Mengyu Wan, Yousong Peng, Songqing Tang, Binbin Xue, Haizhen Zhu
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011443 (2023)
The host always employs various ways to defend against viral infection and spread. However, viruses have evolved their own effective strategies, such as inhibition of RNA translation of the antiviral effectors, to destroy the host's defense barriers.
Externí odkaz:
https://doaj.org/article/d12b3168cb3d42889cf455ca765e4fde
Autor:
Huiyi Li, Shun Liu, Qing Feng, Rilin Deng, Jingjing Wang, Xintao Wang, Renyun Tian, Yan Xu, Shengwen Chen, Qian Liu, Luoling Wang, Xinran Li, Mengyu Wan, Yousong Peng, Songqing Tang, Binbin Xue, Haizhen Zhu
Regulation of translation initiation is essential for maintenance of protein homeostasis and typically involves the phosphorylation of translation initiation factor eIF2α in eukaryotes. In response to stressors, cells employ eIF2α-dependent signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1503805a882eae3855c2d31069035bad
https://doi.org/10.1101/2022.06.07.495079
https://doi.org/10.1101/2022.06.07.495079
Autor:
Binbin Xue, Huiyi Li, Shun Liu, Qing Feng, Yan Xu, Rilin Deng, Shengwen Chen, Jingjing Wang, Xinran Li, Mengyu Wan, Songqing Tang, Haizhen Zhu
Publikováno v:
Cell reports. 40(7)
Interferons (IFNs) are essential in antiviral defense, antitumor effects, and immunoregulatory activities. Although methionine oxidation is associated with various physiological and pathophysiological processes in plants, animals, and humans, its rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b330960c7f341c1feaa6e0d06e6f48
https://pubmed.ncbi.nlm.nih.gov/35977519
https://pubmed.ncbi.nlm.nih.gov/35977519