Výsledky vyhledávání - "Riley Eastmond"

Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1

Autor: Joshua L. Andersen, Manabu Kurokawa, Stephen R. Piccolo, Katherine K. McCormack, Tyler Heaton, Sandeep Kaur, Christina M. Egbert, Eranga R. Balasooriya, Riley Eastmond, A.G. Pramoda Sahankumari, Colin M. Muir, James Woods, Colten M. McEwan, Katie L. Pennington

Supplementary Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd2530ec18e4c0a4f29f3de7cdca194
https://doi.org/10.1158/1541-7786.22527332

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Data from SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1

PTOV1 is an oncogenic protein, initially identified in prostate cancer, that promotes proliferation, cell motility, and invasiveness. However, the mechanisms that regulate PTOV1 remain unclear. Here, we identify 14-3-3 as a PTOV1 interactor and show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6fdb6793264658472e0f6cde850d6ff
https://doi.org/10.1158/1541-7786.c.6545390.v1

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Abstract 1249: 14-3-3 binding stabilizes and sequesters PTOV1 to the cytoplasm during G1

Autor: Katie Pennington, Colten McEwan, James Woods, Colin Muir, A.G. Pramoda Sahankumari, Riley Eastmond, Eranga Balasooriya, Christina Egbert, Joshua Andersen

Publikováno v: Journal of Biological Chemistry. 299:104286

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c242862f302b84e9ac53f853c371051c
https://doi.org/10.1016/j.jbc.2023.104286

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Abstract 1469: 14-3-3 binding during G1 stabilizes and sequesters PTOV1 to the cytoplasm

Autor: Katie L. Pennington, Colten M. McEwan, James Woods, Colin M. Muir, A G Pramoda Sahankumari, Riley Eastmond, Eranga R. Balasooriya, Christina M. Egbert, Katherine K. McCormack, Joshua L. Andersen

Publikováno v: Cancer Research. 82:1469-1469

Cells must respond to changing environments by modulating signaling and gene expression patterns to maintain homeostasis, health, and viability. Inappropriate responses lead to disease processes, such as cancer. Despite improvements in targeted treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::971a37584c5b79c84033cdcead1bc188
https://doi.org/10.1158/1538-7445.am2022-1469

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