Výsledky vyhledávání - "Riley C. Myers"

Follicular dendritic cells: dynamic antigen libraries

Autor: Balthasar A. Heesters, Riley C. Myers, Michael C. Carroll

Publikováno v: Nature Reviews Immunology. 14:495-504

Follicular dendritic cells (FDCs) are essential for high-affinity antibody production and for the development of B cell memory. Historically, FDCs have been characterized as 'accessory' cells that passively support germinal centre (GC) responses. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dee27ec182daae220d42961391930e8
https://doi.org/10.1038/nri3689

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Interleukin 17–producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

Autor: PingAr Yang, Robert W. Williams, David D. Chaplin, Hui-Chen Hsu, Robert H. Carter, Qi Wu, Albert Tousson, Jay K. Kolls, John D. Mountz, Tanja Guentert, Jian Chen, John H. Wang, Andrea L Stanus, John S. Yi, Robin G. Lorenz, Riley C. Myers, Hui Xu, Thuc-vy L. Le

Publikováno v: Nature Immunology. 9:166-175

Interleukin 17 (IL-17) is a cytokine associated with inflammation, autoimmunity and defense against some bacteria. Here we show that IL-17 can promote autoimmune disease through a mechanism distinct from its proinflammatory effects. As compared with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4ad51e1350b44c98a8490e4abded1b
https://doi.org/10.1038/ni1552

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Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center response

Autor: Riley C, Myers, R Glenn, King, Robert H, Carter, Louis B, Justement

Publikováno v: European journal of immunology. 43(2)

CD19-deficient mice were used as a model to study follicular dendritic cell (FDC) activation because these mice have normal numbers of FDC-containing primary follicles, but lack the ability to activate FDCs or form GCs. It was hypothesized that CD19

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4fa3461ff1155a1a31eaab0d37c08f68
https://pubmed.ncbi.nlm.nih.gov/23112125

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Marginal zone B cells regulate antigen capture by marginal zone macrophages

Autor: Jeremy B. Foote, Louis B. Justement, Larry E. Freeberg, Yuying You, John F. Kearney, Robert H. Carter, Riley C. Myers

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 186(4)

The marginal zone (MZ) of the mouse spleen contains macrophages that express receptors that trap pathogens, including the scavenger receptor macrophage receptor with a collagenous structure and the C-type lectin specific intracellular adhesion molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7e0b46e5eb6874390f34214d58f011
https://pubmed.ncbi.nlm.nih.gov/21257969

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B cells fail to mature or form LZ despite GC formation in CD19‐deficient mice

Autor: Riley C. Myers, Robert H. Carter

Publikováno v: The FASEB Journal. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1ca2e9c02a5be15cde96df960a9ea5a
https://doi.org/10.1096/fasebj.22.1_supplement.847.14

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Germinal Center Structure and Function: Lessons form CD19

Autor: Robert H. Carter, Riley C. Myers

The germinal center is a critical locus in the production of protective immunity, but its function is poorly understood. Studies of mutant forms of CD19 revealed differences in signaling in different compartments inside the germinal center, and struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b124215839120fd93e554a0ce482773
https://europepmc.org/articles/PMC2346595/

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