Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rikuhiro G. Yamada"'
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Autor:
Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R. Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, Shota Y. Yoshida, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Rikuhiro G. Yamada, Shoi Shi, Kazunari Miyamichi, Kenta Sumiyama, Hiroshi Kiyonari, Etsuo A. Susaki, Hiroki R. Ueda
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The homeostatic regulation of sleep is characterized by rebound sleep after prolonged wakefulness, but the molecular and cellular mechanisms underlying this regulation are still unknown. In this study, we show that Ca2+/calmodulin-dependent
Externí odkaz:
https://doaj.org/article/1820ed7e972241e4b90b7d9e83e720d1
Autor:
Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Yuki Arisato, Rei-ichiro Ohno, Maki Ukai-Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, Hideki Ukai, Kazunari Miyamichi, Takashi Okada, Kenta Sumiyama, Hiroshi Kiyonari, Hiroki R. Ueda
Publikováno v:
PLoS Biology, Vol 20, Iss 10 (2022)
The reduced sleep duration previously observed in Camk2b knockout mice revealed a role for Ca2+/calmodulin-dependent protein kinase II (CaMKII)β as a sleep-promoting kinase. However, the underlying mechanism by which CaMKIIβ supports sleep regulati
Externí odkaz:
https://doaj.org/article/c422f3677b6849ceb5f7d2c1b49d07ab
Autor:
Tomoyuki Mano, Ken Murata, Kazuhiro Kon, Chika Shimizu, Hiroaki Ono, Shoi Shi, Rikuhiro G. Yamada, Kazunari Miyamichi, Etsuo A. Susaki, Kazushige Touhara, Hiroki R. Ueda
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 2, Pp 100038- (2021)
Summary: Recent advancements in tissue clearing technologies have offered unparalleled opportunities for researchers to explore the whole mouse brain at cellular resolution. With the expansion of this experimental technique, however, a scalable and e
Externí odkaz:
https://doaj.org/article/1201485fe4114ae4957735926d3fa8ad
Autor:
Rikuhiro G. Yamada, Hiroki R. Ueda
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2020)
Rapid-eye movement (REM) sleep is a paradoxical sleep state characterized by brain activity similar to wakefulness, rapid-eye-movement, and lack of muscle tone. REM sleep is a fundamental brain function, evolutionary conserved across species, includi
Externí odkaz:
https://doaj.org/article/a09122d4cf8d4c26b62f606e313bec4c
Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation
Autor:
Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Riina R. Takahashi, Rikuhiro G. Yamada, Shoi Shi, Kenta Sumiyama, Hiroshi Kiyonari, Etsuo A. Susaki, Hiroki R. Ueda
The homeostatic regulation of sleep is characterized by rebound sleep after prolonged wakefulness, but the molecular and cellular mechanisms underlying this regulation are still unknown. We show here that CaMKII-dependent activity control of parvalbu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5bd4b9d9ddb6494fa3545ae2cac0df
https://doi.org/10.1101/2023.04.29.537929
https://doi.org/10.1101/2023.04.29.537929
Autor:
Rikuhiro G. Yamada, Hiroki R. Ueda
Publikováno v:
EMBO J
Circadian rhythms regulate diverse aspects of gastrointestinal physiology ranging from the composition of microbiota to motility. However, development of the intestinal circadian clock and detailed mechanisms regulating circadian physiology of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e91460771bd6a848d3a003f3b101aa
https://europepmc.org/articles/PMC8762543/
https://europepmc.org/articles/PMC8762543/
Autor:
Mari Kaneko, Rei-ichiro Ohno, Shota Yoshida, Koji L. Ode, Tomoki T Mitani, Zhiqing Wen, Hiroshi Fujishima, Maki Ukai-Tadenuma, Kazunari Miyamichi, Junko Yoshida Garçon, Rikuhiro G. Yamada, Hiroki R. Ueda, Hiroshi Kiyonari, Shoi Shi, Hideki Ukai, Daisuke Tone, Takashi Okada, Yoshiki Nagashima, Kenta Sumiyama, Qianhui Zhang, Katsuhiko Matsumoto
The reduced sleep duration observed in Camk2a and Camk2b knockout mice revealed the role of Ca2+/calmodulin-dependent protein kinase II (CaMKII)α/CAMKIIβ as sleep-promoting kinases and lead to the phosphorylation hypothesis of sleep. However, the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71aa3b5633f78c70307a6e33e5029142
https://doi.org/10.1101/2021.10.11.463945
https://doi.org/10.1101/2021.10.11.463945
Autor:
Yigang Shen, Hiroki R. Ueda, Yusufu Aishan, Yo Tanaka, Rikuhiro G. Yamada, Hiroyuki Moriguchi, Genki N. Kanda, Nobutoshi Ota
Publikováno v:
Analytical Sciences. 35:1141-1147
Microfluidic devices are important platforms to culture and observe biological tissues. Compared with conventional setups, microfluidic devices have advantages in perfusion, including an enhanced delivery of nutrients and gases to tissues. However, e
Autor:
Shoi Shi, Rikuhiro G. Yamada, Kazunari Miyamichi, Chika Shimizu, Hiroki R. Ueda, Kazuhiro Kon, Etsuo A. Susaki, Tomoyuki Mano, Ken Murata, Hiroaki Ono, Kazushige Touhara
Recent advancements in tissue clearing technologies have offered unparalleled opportunities for researchers to explore the whole mouse brain at cellular resolution. With the expansion of this experimental technique, however, a scalable and easy-to-us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5a9f8789ec98a63c950ed955b63ebc8
https://doi.org/10.1101/2020.08.28.271031
https://doi.org/10.1101/2020.08.28.271031
Autor:
Rikuhiro G. Yamada, Hiroki R. Ueda
Publikováno v:
Proceedings of the National Academy of Sciences. 114:5069-5071
In the globalized modern society, the world is continuously moving 24 h a day 7 d a week. Prominent cities on the earth can be seen brightly lit at night from outer space. People on earth have daily (circadian) rhythms based more on their social circ