Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Riku Louhimo"'
Autor:
Leo Meriranta, Annika Pasanen, Riku Louhimo, Alejandra Cervera, Amjad Alkodsi, Matias Autio, Minna Taskinen, Ville Rantanen, Marja-Liisa Karjalainen-Lindsberg, Harald Holte, Jan Delabie, Rainer Lehtonen, Sampsa Hautaniemi, Sirpa Leppä
Publikováno v:
Haematologica, Vol 102, Iss 5 (2017)
Externí odkaz:
https://doaj.org/article/28cc657606594d109e90f141258ab1de
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164023 (2016)
A modern biomedical research project can easily contain hundreds of analysis steps and lack of reproducibility of the analyses has been recognized as a severe issue. While thorough documentation enables reproducibility, the number of analysis program
Externí odkaz:
https://doaj.org/article/62217ed05f944b61be8b09d1793e3648
Autor:
Minna Taskinen, Riku Louhimo, Satu Koivula, Ping Chen, Ville Rantanen, Harald Holte, Jan Delabie, Marja-Liisa Karjalainen-Lindsberg, Magnus Björkholm, Øystein Fluge, Lars Møller Pedersen, Karin Fjordén, Mats Jerkeman, Mikael Eriksson, Sampsa Hautaniemi, Sirpa Leppä
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91031 (2014)
Despite improved survival for the patients with diffuse large B-cell lymphoma (DLBCL), the prognosis after relapse is poor. The aim was to identify molecular events that contribute to relapse and treatment resistance in DLBCL.We analysed 51 prospecti
Externí odkaz:
https://doaj.org/article/760556e9d79c4d1f8fbe71cf2f3c2120
Autor:
Outi Monni, Heikki Joensuu, Krister Wennerberg, Tero Aittokallio, Olli Kallioniemi, Stina M. Syrjänen, Reidar Grénman, Harri Sihto, Mikko Kivento, Evgeny Kulesskiy, Astrid Murumägi, Bhagwan Yadav, Riku Louhimo, Piia-Riitta Karhemo, Tatiana Lepikhova
Table S1. Genes included in the targeted next-generation sequencing HNSCC gene panel. Table S2. Compounds (n=220) and their drug classes/targets used in the drug screen. Table S3. qPCR primers and qPCR vs GE_microarray correlation. Table S4. Drug sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ae8f8ec407eaf883076faa5c626fba
https://doi.org/10.1158/1535-7163.22505545
https://doi.org/10.1158/1535-7163.22505545
Autor:
Outi Monni, Heikki Joensuu, Krister Wennerberg, Tero Aittokallio, Olli Kallioniemi, Stina M. Syrjänen, Reidar Grénman, Harri Sihto, Mikko Kivento, Evgeny Kulesskiy, Astrid Murumägi, Bhagwan Yadav, Riku Louhimo, Piia-Riitta Karhemo, Tatiana Lepikhova
Figure S1. Heat map of drug responses of 220 compounds across 45 HPV negative cell lines. Figure S2. DSS scores and grouping of the used drugs based on their functional categories. Figure S3. An effect of transient knock-down of RAB25 and FAM83H to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4763a3b0d3e785c0b4b02ef8ac8391
https://doi.org/10.1158/1535-7163.22505548
https://doi.org/10.1158/1535-7163.22505548
Autor:
Outi Monni, Heikki Joensuu, Krister Wennerberg, Tero Aittokallio, Olli Kallioniemi, Stina M. Syrjänen, Reidar Grénman, Harri Sihto, Mikko Kivento, Evgeny Kulesskiy, Astrid Murumägi, Bhagwan Yadav, Riku Louhimo, Piia-Riitta Karhemo, Tatiana Lepikhova
There is an unmet need for effective targeted therapies for patients with advanced head and neck squamous cell carcinoma (HNSCC). We correlated gene expression, gene copy numbers, and point mutations in 45 human papillomavirus–negative HNSCC cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c1e24c64e9f023b80e41c77116c8b2
https://doi.org/10.1158/1535-7163.c.6538108.v1
https://doi.org/10.1158/1535-7163.c.6538108.v1
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Tables S1-S4. MMPs which are significantly over-expressed in melanoma cell lines compared to the mean expression of all cancer cell lines in the datasets with over 15 melanoma cell lines (S1); Outlier analysis of MMP16 copy number gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c7e98651081946cdd8bfdac15223cd
https://doi.org/10.1158/0008-5472.22404674
https://doi.org/10.1158/0008-5472.22404674
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Data. Supplementary Materials and Methods and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de16af2dab751c57fb9d7db94af2d4e
https://doi.org/10.1158/0008-5472.22404686.v1
https://doi.org/10.1158/0008-5472.22404686.v1
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Figures S1-S9. MMP14 which is over-expressed in melanoma cell lines was not associated with patient survival (S1); Vasculature and morphology of human melanoma tumors (S2); MMP16 expression in WM852 cells and its correlation with tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3f3780163302e48356405ab0c71f2c
https://doi.org/10.1158/0008-5472.22404680.v1
https://doi.org/10.1158/0008-5472.22404680.v1
Autor:
Rainer Lehtonen, Alejandra Cervera, Amjad Alkodsi, Sampsa Hautaniemi, Sirpa Leppä, Harald Holte, Leo Meriranta, Riku Louhimo, Kaiyang Zhang, Annika Pasanen, Suvi-Katri Leivonen
Diffuse large B-cell lymphoma (DLBCL) is a biologically and clinically heterogeneous disease whose personalized clinical management requires robust molecular stratification. Here, we show that somatic hypermutation (SHM) patterns constitute a marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e2d5c83b1c3b52517b502a893abaf7
http://hdl.handle.net/10138/314705
http://hdl.handle.net/10138/314705