Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Riku Koivusalo"'
Autor:
Riku Koivusalo, Juha Välimäki
Publikováno v:
Acta Ophthalmologica. 98:305-309
PURPOSE To study the effect of glaucoma drainage implant (GDI) surgery on corneal topography during the first postoperative year. METHODS Twenty-one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 GDI. Corneal topography mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdda3bf9b1e417e5bb53af7ca1cf567d
https://doi.org/10.1111/aos.14247
https://doi.org/10.1111/aos.14247
Autor:
Klaus Elenius, Teemu T. Junttila, Randall S. Johnson, Henrik Söderström, Jukka Westermarck, Tim H. Holmström, Sakari Hietanen, Matti Sankinen, Riku Koivusalo, Anastassios C. Papageorgiou, Antoine Mialon
Publikováno v:
Molecular and Cellular Biology. 25:5040-5051
DNA topoisomerase I (Topo I) is a molecular target for the anticancer agent topotecan in the treatment of small cell lung cancer and ovarian carcinomas. However, the molecular mechanisms by which topotecan treatment inhibits cancer cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc2f263e5ef19af4bd80c2f044cf108
https://doi.org/10.1128/mcb.25.12.5040-5051.2005
https://doi.org/10.1128/mcb.25.12.5040-5051.2005
Publikováno v:
Molecular Pharmacology. 68:372-382
Constant expression of E6 and E7 mRNA by high-risk human papillomaviruses (HPV) abrogates p53 and retinoblastoma protein function, respectively, and is essential for the development of cervical cancer. Despite E6, some chemotherapy drugs can stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a73127b479dc87adb5bba08ed87754
https://doi.org/10.1124/mol.105.011189
https://doi.org/10.1124/mol.105.011189
Autor:
Sakari Hietanen, Riku Koivusalo
Publikováno v:
Cancer Biology & Therapy. 3:1177-1183
Metastatic cervical cancer remains a clinical problem. The development of more efficient treatment modalities and the optimal use of chemo- and radiotherapy require better understanding of their impact on regulation of cell survival and apoptosis, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcbe2aee3043637c80203954398590a
https://doi.org/10.4161/cbt.3.11.1340
https://doi.org/10.4161/cbt.3.11.1340
Publikováno v:
Cancer research. 66(24)
p53 is degraded in cervical cancer cells by the human papillomavirus E6 and can be stabilized with short interfering RNA (siRNA) molecules targeting E6 mRNA. In this in vitro study, we show that E6 siRNA–induced p53 activation is transient in HeLa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2f8aeeb487cb435991a4d222c5a96b
https://pubmed.ncbi.nlm.nih.gov/17178878
https://pubmed.ncbi.nlm.nih.gov/17178878
Publikováno v:
Cancer research. 62(24)
Recent clinical trials comparing concurrent chemotherapy and radiation with radiation alone in cervical cancer have shown that chemoradiation reduces the risk of death by 30-50%. Despite the clinical success, treatment responses at the cellular level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6505b804343431d8d5181245a1524c4b
https://pubmed.ncbi.nlm.nih.gov/12499281
https://pubmed.ncbi.nlm.nih.gov/12499281