Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rikki R Bharadwaj"'
Autor:
Alla Buzina, Mandy Y M Lo, Angela Moffett, Akitsu Hotta, Eden Fussner, Rikki R Bharadwaj, Peter Pasceri, J Victor Garcia-Martinez, David P Bazett-Jones, James Ellis
Publikováno v:
PLoS Genetics, Vol 4, Iss 4, p e1000051 (2008)
The Locus Control Region (LCR) requires intronic elements within beta-globin transgenes to direct high level expression at all ectopic integration sites. However, these essential intronic elements cannot be transmitted through retrovirus vectors and
Externí odkaz:
https://doaj.org/article/927a29181dd94ee4b2b4d1b37f6fbd61
Autor:
Benoit You, Lisa Wang, Christophe Le Tourneau, Bayardo Perez-Ordonez, Rikki R. Bharadwaj, E.X. Chen, Lillian L. Siu, Vijay Mann, Andrea Jarvi, Suzanne Kamel-Reid
Publikováno v:
American Journal of Clinical Oncology. 35:255-260
Despite the efficacy of gemcitabine-platinum regimen, the outcome of patients with recurrent and/or metastatic nasopharyngeal carcinoma (RM NPC) is poor. A phase II trial was conducted to determine the efficacy of erlotinib, given as maintenance ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c532d2bcff383a133b76ee452a1ce5f
https://doi.org/10.1097/coc.0b013e31820dbdcc
https://doi.org/10.1097/coc.0b013e31820dbdcc
Autor:
Patrick J. Gullane, Jonathan C. Irish, Bayardo Perez-Ordonez, Christina MacMillan, Melania Pintilie, Suzanne Kamel-Reid, Patricia P Reis, Mahadeo A. Sukhai, Rikki R. Bharadwaj, Jerry Machado
Publikováno v:
Cancer. 113:3169-3180
BACKGROUND. The authors have previously shown that overexpression of claudin 1 (CLDN1) is associated with advanced disease stage in oral squamous cell carcinomas (OSCCs). Their goal was to examine CLDN1 expression in a large series of primary OSCCs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179b405f3506ce372684338cfd85bbf9
https://doi.org/10.1002/cncr.23934
https://doi.org/10.1002/cncr.23934
Autor:
Soheila A. Hamadanizadeh, Rikki R. Bharadwaj, Andre C. Schuh, Richard A. Wells, Mahadeo A. Sukhai, Yali Xuan, Lap Shu Alan Chan, Suzanne Kamel-Reid, Tong Zhang, Mariam Thomas
Publikováno v:
Oncogene. 27:4666-4677
Acute promyelocytic leukemia (APL) is characterized by reciprocal balanced chromosomal translocations involving retinoic acid receptor-alpha (RARalpha). RARalpha heterodimerizes with the retinoid X receptor-alpha (RXRalpha) and transcriptionally regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d91e3562182c4f9a0f0a632048af491
https://doi.org/10.1038/onc.2008.106
https://doi.org/10.1038/onc.2008.106
Publikováno v:
Molecular Therapy. 10:27-36
Retrovirus silencing in stem cells produces silent or variegated provirus. Additional memory and extinction mechanisms act during differentiation. Here we show that retrovirus is silent or variegated in mouse embryonic stem (ES) cells that are de nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3232aac8459f19571e95f0c012111b7
https://doi.org/10.1016/j.ymthe.2004.04.007
https://doi.org/10.1016/j.ymthe.2004.04.007
Autor:
Tanya Sukonnik, Rikki R. Bharadwaj, James Ellis, Félix Recillas-Targa, Peter Pasceri, Adam G. West, Cameron S. Osborne, Dylan Pannell, Shuyuan Yao
Publikováno v:
Nucleic Acids Research. 31:5317-5323
Silencing of retrovirus vectors poses a significant obstacle to genetic manipulation of stem cells and their use in gene therapy. We describe a mammalian silencer blocking assay using insulator elements positioned between retrovirus silencer elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564906d1cc5f9589887e851f19d1aa69
https://doi.org/10.1093/nar/gkg742
https://doi.org/10.1093/nar/gkg742
Autor:
Rikki R. Bharadwaj, James C. Shaw, Charis Kepron, Danny Ghazarian, Suzanne Kamel-Reid, Patricia P Reis
Publikováno v:
European journal of dermatology : EJD. 19(3)
Auteur(s) : Charis Kepron1, Patricia Reis2, Rikki Bharadwaj2, James Shaw3, Suzanne Kamel-Reid1,2,4, Danny Ghazarian1,4 1Department of Laboratory Medicine and Pathobiology, University of Toronto, Room 110, 100 College Street, Toronto, Ontario M5G 1L5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e70d51cbef67bac54b523ef65107cb
https://pubmed.ncbi.nlm.nih.gov/19307168
https://pubmed.ncbi.nlm.nih.gov/19307168
Autor:
Eden Fussner, Angela Moffett, James Ellis, Mandy Y. M. Lo, Alla Buzina, David P. Bazett-Jones, Peter Pasceri, Rikki R. Bharadwaj, Akitsu Hotta, J. Victor Garcia-Martinez
Publikováno v:
PLoS Genetics, Vol 4, Iss 4, p e1000051 (2008)
PLoS Genetics
PLoS Genetics
The Locus Control Region (LCR) requires intronic elements within β-globin transgenes to direct high level expression at all ectopic integration sites. However, these essential intronic elements cannot be transmitted through retrovirus vectors and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75477a6af3c45ce414ff21a9770bc56
http://europepmc.org/articles/PMC2271131?pdf=render
http://europepmc.org/articles/PMC2271131?pdf=render
Autor:
Sorin Draghici, Rui Pires Martins, Stephen A. Krawetz, James Ellis, Rikki R. Bharadwaj, Zhandong Liu, G. Charles Ostermeier
The human beta-globin locus is home to five genes that are regulated in a tissue-specific and developmental stage-specific manner. While the exact mode of expression remains somewhat enigmatic, a significant effort has been focused at the locus contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a883ded2797caee0e9759c1f6185ad
https://europepmc.org/articles/PMC162328/
https://europepmc.org/articles/PMC162328/
Publikováno v:
Blood. 101(4)
Human β-globin transgenes regulated by the locus control region (LCR) express at all integration sites in transgenic mice. For such LCR activity at ectopic sites, the 5′HS3 element requires the presence of the AT-rich region (ATR) in β-globin int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64b2f11275391bbe8792a8b7a50d33f
https://pubmed.ncbi.nlm.nih.gov/12393478
https://pubmed.ncbi.nlm.nih.gov/12393478