Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Rikke, Nørregaard"'
Autor:
Emil Gregersen, Jean-Claude Kresse, Jasmine Cicek Leifing Atay, Anders Toftegaard Boysen, Peter Nejsum, Marco Eijken, Rikke Nørregaard
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Renal fibrosis, characterized by excessive extracellular matrix accumulation, leads to a progressive decline of renal function and is a common endpoint of chronic kidney disease (CKD). Current treatments primarily focus on managing underlying disease
Externí odkaz:
https://doaj.org/article/8e3c52e63b684d68b09e102db319da58
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/78c6603afdc942518224e87734135c44
Autor:
Michael Schou Jensen, Isabela Bastos Binotti Abreu de Araujo, Henricus A.M. Mutsaers, Rikke Nørregaard
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Objective Glomerular filtration rate (GFR) is a key indicator of renal function. In both clinical practice and pre-clinical research, serum levels of endogenous filtration markers, such as creatinine, are often used to estimate GFR. However,
Externí odkaz:
https://doaj.org/article/10a67116d8b54d178831941a55cc8b1e
Autor:
Jacob Rudjord Therkildsen, Stine Julie Tingskov, Michael Schou Jensen, Helle Praetorius, Rikke Nørregaard
Publikováno v:
Physiological Reports, Vol 11, Iss 22, Pp n/a-n/a (2023)
Abstract Renal fibrosis is tightly associated with chronic kidney disease, irrespective of the underlying pathogenesis. We previously demonstrated mild antifibrotic effects of targeting the P2X7 receptor in a pyelonephritis model. Reduced P2X7R‐act
Externí odkaz:
https://doaj.org/article/ad10cd4bbc1b4df7878d0986cace4659
Autor:
Henricus A. M. Mutsaers, Michael Schou Jensen, Jean-Claude Kresse, Stine Julie Tingskov, Mia Gebauer Madsen, Rikke Nørregaard
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective Renal fibrosis is one of the main pathophysiological processes underlying the progression of chronic kidney disease and kidney allograft failure. In the past decades, overwhelming efforts have been undertaken to find druggable targ
Externí odkaz:
https://doaj.org/article/22d6c520707049509ef450fcb7fcc673
Autor:
Nigopan Gopalasingam, Kristian Hylleberg Christensen, Kristoffer Berg Hansen, Roni Nielsen, Mogens Johannsen, Lars Christian Gormsen, Ebbe Boedtkjer, Rikke Nørregaard, Niels Møller, Henrik Wiggers
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background The ketone body 3‐hydroxybutyrate (3‐OHB) increases cardiac output (CO) in patients with heart failure through unknown mechanisms. 3‐OHB activates the hydroxycarboxylic acid receptor 2 (HCA2), which increases prostaglandins and suppr
Externí odkaz:
https://doaj.org/article/d7894fbb62064170acc8b0e3d4e8cc34
Autor:
Martin Tepel, Firas F. Alkaff, Daan Kremer, Stephan J. L. Bakker, Olivier Thaunat, Subagini Nagarajah, Qais Saleh, Stefan P. Berger, Jacob van den Born, Nicoline V. Krogstrup, Marie B. Nielsen, Rikke Nørregaard, Bente Jespersen, Nadja Sparding, Federica Genovese, Morten A. Karsdal, Daniel G. K. Rasmussen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Delayed graft function after kidney transplantation is common and increases morbidity and health care costs. There is evidence that endotrophin, a specific fragment of pro-collagen type VI, promotes the inflammatory response in kidney diseas
Externí odkaz:
https://doaj.org/article/dc8376e1ebb242f882d7aef601a70e13
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss 1, Pp 4-13 (2022)
Prostaglandin E2 (PGE2), a lipid mediator produced by the cyclooxygenase enzyme system, is the main prostaglandin in the kidney. PGE2 is involved in various physiological and pathophysiological processes in the kidney, including renal hemodynamics, w
Externí odkaz:
https://doaj.org/article/f4a0758dd3974a2fb4653f21e13c32f1
Autor:
Søren Kissow Lildal, Esben Søvsø Szocska Hansen, Christoffer Laustsen, Rikke Nørregaard, Lotte Bonde Bertelsen, Kirsten Madsen, Camilla W. Rasmussen, Palle Jörn Sloth Osther, Helene Jung
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Introduction Intrarenal backflow (IRB) is known to occur at increased intrarenal pressure (IRP). Irrigation during ureteroscopy increases IRP. Complications such as sepsis is more frequent after prolonged high-pressure ureteroscopy. We evaluated a ne
Externí odkaz:
https://doaj.org/article/c2095f61c7154b7781b6d3eef55abb29
Autor:
Nadja Sparding, Federica Genovese, Daniel Guldager Kring Rasmussen, Morten A. Karsdal, Nicoline V. Krogstrup, Marie Bodilsen Nielsen, Mads Hornum, Subagini Nagarajah, Henrik Birn, The CONTEXT Study Group, Bente Jespersen, Martin Tepel, Rikke Nørregaard
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 792 (2023)
Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker
Externí odkaz:
https://doaj.org/article/6b7179723dfd45a48c824c320306cac4