Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Riki Toita"'
Publikováno v:
Journal of Xenobiotics, Vol 13, Iss 4, Pp 775-810 (2023)
Bisphenol A (BPA; 4,4′-isopropylidenediphenol) is a well-known endocrine disruptor. Most human exposure to BPA occurs through the consumption of BPA-contaminated foods. Cardiovascular or cardiometabolic diseases such as diabetes, obesity, hypertens
Externí odkaz:
https://doaj.org/article/e2e30b95d1b14ebd9011f9ef624d542d
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 198 (2019)
Biomedical applications of poly(ether ether ketone) (PEEK) are hindered by its inherent bioinertness and lack of osseointegration capability. In the present study, to enhance osteogenic activity and, hence, the osseointegration capability of PEEK, we
Externí odkaz:
https://doaj.org/article/10f4534f9f4141beba0a98f3acff0cf8
Publikováno v:
Acta Biomaterialia. 154:583-596
An appropriate immune microenvironment, governed by macrophages, is essential for rapid tissue regeneration after biomaterial implantation. The macrophage phenotypes, M1 (inflammatory) and M2 (anti-inflammatory/healing), exert opposing effects on the
Publikováno v:
ACS Biomaterials Science & Engineering. 7:2530-2537
The presence of intracellular signal transduction and its abnormal activities in many cancers has potential for medical and pharmaceutical applications. We recently developed a protein kinase C α (PKCα)-responsive gene carrier for cancer-specific g
Autor:
Jeong Hun Kang, Riki Toita
Publikováno v:
Toxicology Letters. 332:1-6
Non-alcoholic fatty liver disease (NAFLD) can be typically classified into two subgroups: non-alcoholic fatty liver and non-alcoholic steatohepatitis. Mouse models of NAFLD are useful tools for understanding the pathogenesis and progression of NAFLD
Publikováno v:
Chemical Communications. 56:8253-8256
Nanomedicines that suppress macrophage-mediated chronic inflammation are important therapeutics for many inflammatory diseases. The small-sized (
Autor:
Naoyuki Fukuda, Riki Toita, Akira Tsuchiya, Kanji Tsuru, Kunio Ishikawa, Yoshihide Mori, Sunarso
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 173:36-42
Poly(ether ether ketone) (PEEK) has emerged as an alternative endosseous material to metal implants mainly because of its lack of allergic sensitivity and radiolucency, while maintaining similar mechanical properties with bone. However, a disadvantag
Autor:
Naoyuki Fukuda, Masayuki Kanazawa, Kanji Tsuru, Akira Tsuchiya, Kunio Ishikawa, Sunarso, Riki Toita, Yoshihide Mori, Yasuharu Nakashima
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
This study was aimed to investigate the osseointegration ability of poly(ether ether ketone) (PEEK) implants with modified surface roughness and/or surface chemistry. The roughened surface was prepared by a sandblast method, and the phosphate groups
Autor:
Riki Toita1 toita-r@aist.go.jp, Takahito Kawano2, Satoshi Fujita1, Masaharu Murata2, Jeong-Hun Kang3 jrjhkang@ncvc.go.jp
Publikováno v:
Journal of Toxicologic Pathology. 2018, Vol. 31 Issue 1, p43-47. 5p.
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 330
Pressure ulcers (PUs) have no cure and are of significant health and economic concern worldwide, owing to the increasing population of elderly individuals at high risk for PU and who have impaired tissue repair. Macrophages play a pivotal role in PU