Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rika van Huizen"'
Publikováno v:
Biochemical and Biophysical Research Communications. 357:480-486
RNA interference (RNAi), a post-transcriptional gene silencing mechanism originally described in Caenorhabditis elegans, involves sequence-specific mRNA degradation mediated by double-stranded RNAs (dsRNAs). Passive dsRNA uptake has been uniquely obs
Autor:
Rika Van Huizen, Ronald A. Li, Janet Chyng-Jiau Lin Zhang, Ka-Wing Au, Linzhao Cheng, Suk Ying Tsang, Chu-Pak Lau, Kevin Lai, CW Wong, Hung-Fat Tse, Tian Xue, Kai Wang, Gui-Rong Li, Zhaohui Ye
Publikováno v:
STEM CELLS. 23:1526-1534
Pluripotent embryonic stem cells (ESCs) possess promising potential for cell-based therapies, but their electrophysiological properties have not been characterized. Here we describe the presence of ionic currents in mouse (m) and human (h) ESCs and t
Publikováno v:
Journal of Biological Chemistry. 278:15558-15564
The unfolded protein response, which is activated in response to the loss of endoplasmic reticulum (ER) Ca(2+) homeostasis and/or the accumulation of misfolded, unassembled, or aggregated proteins in the ER lumen, involves both transcriptional and tr
Publikováno v:
Plant Physiology. 128:1379-1389
Growth of young pea (Pisum sativum) fruit (pericarp) requires developing seeds or, in the absence of seeds, treatment with gibberellin (GA) or auxin (4-chloroindole-3-acetic acid). This study examined the role of seeds and hormones in the regulation
Publikováno v:
Science. 285:1565-1569
Targeting of protein modification enzymes is a key biochemical step to achieve specific and effective posttranslational modifications. Two alternatively spliced ZIP1 and ZIP2 proteins are described, which bind to both Kvbeta2 subunits of potassium ch
Autor:
Shizuo Ikeyama, Myriam Gorospe, Jennifer L. Martindale, Gertrude C. Kokkonen, Rika van Huizen, Xiantao Wang, Nikki J. Holbrook, Andrej Podlutsky, Ji Li
Publikováno v:
The Journal of biological chemistry. 278(19)
Aging is generally accompanied by reduced tolerance to oxidative stress and altered responsiveness to proliferative signals. We have shown that hepatocytes derived from aged rats (24-26 months) exhibit greater sensitivity to H(2)O(2) treatment and re
Autor:
Karen Miller, Ronald W. Raab, De Mao Chen, William S. Stark, Min Li, Zhi Chun Lai, Randall D. Shortridge, Ying Li, Rika van Huizen
Publikováno v:
The EMBO journal. 17(8)
Drosophila INAD, which contains five tandem protein interaction PDZ domains, plays an important role in the G protein-coupled visual signal transduction. Mutations in InaD alleles display mislocalization of signaling molecules of phototransduction wh
Publikováno v:
Cell Research. 18:S129-S129
Ectopic expression of systemic RNA interference defective protein (SID-1) in embryonic stem cells: Implications for high-throughput gene screening
Publikováno v:
FEBS Letters. (1):107-111
The Shaker type voltage-gated potassium (K+) channel consists of four pore-forming Kv alpha subunits. The channel expression and kinetic properties can be modulated by auxiliary hydrophilic Kv beta subunits via formation of heteromultimeric Kv alpha-
Publikováno v:
Cell Research; Aug2008 Supplement, Vol. 18, pS129-S129, 1p