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pro vyhledávání: '"Rika Yamamoto-Fujita"'
Autor:
Yaeta Endo, Satoshi Fujita, Hideo Kise, Masahiro Iwakura, Rika Yamamoto-Fujita, Shinya Y. Sawata, Kazunari Taira
Publikováno v:
Journal of Medicinal Chemistry. 45:1598-1606
We recently isolated an aptamer that binds to the Tat protein of HIV-1 with extremely high affinity and specificity (Yamamoto, R.; et al. Genes Cells 2000, 5, 371.). In the present study, we exploited this strong binding to develop a novel coupling m
Publikováno v:
Analytical chemistry. 77(17)
The specificity and affinity of aptamers for their cognate ligands are comparable to those of antibodies for antigens. To use aptamers effectively in high-throughput assays in a microarray format, to analyze various analytes, we developed a strategy